| Title : Diethylmesoxalate hydrate, a new irreversible inhibitor of cholinesterases - Voss_1979_Experientia_35_583 |
| Author(s) : Voss G , Neumann R |
| Ref : Experientia , 35 :583 , 1979 |
|
Abstract :
Bovine erythrocyte acetylcholinesterase and human plasma cholinesterase are irreversibly inhibited by diethylmesoxalate hydrate, the inhibition potency being comparable to that of certian insecticidal organophosphates and carbamates. Insect cholinesterases, however, appear to be much less affected by diethylmesoxalate hydrate. The compound was also found to inhibit the hydrolysis of paraoxon by rabbit plasma A-esterase, but in a reversible mode. |
| PubMedSearch : Voss_1979_Experientia_35_583 |
| PubMedID: 446648 |
| Inhibitor | Diethylmesoxalate |
Voss G, Neumann R (1979)
Diethylmesoxalate hydrate, a new irreversible inhibitor of cholinesterases
Experientia
35 :583
Voss G, Neumann R (1979)
Experientia
35 :583