| Title : Sesquiterpenoids and lignans from the roots of Valeriana officinalis L - Wang_2011_Chem.Biodivers_8_1908 |
| Author(s) : Wang PC , Ran XH , Chen R , Luo HR , Ma QY , Liu YQ , Hu JM , Huang SZ , Jiang HZ , Chen ZQ , Zhou J , Zhao YX |
| Ref : Chem Biodivers , 8 :1908 , 2011 |
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Abstract :
Two new guaiane-type sesquiterpenoids, valerol A (1) and kessyl 3-acetate (2), together with nine known compounds, valeracetate (3), anismol A (4), orientalol C (5), spatulenol (6), 4alpha,10alpha-epoxyaromadendrane (7), (+)-8-hydroxypinoresinol (8), pinorespiol (9), pinoresinol 4-O-beta-D-glucopyranoside (10), and 8-hydroxypinoresinol 4'-O-beta-D-glucopyranoside (11) were isolated from the roots of Valeriana officinalis. The structures and relative configurations of 1 and 2 were elucidated on the basis of spectroscopic methods (1D- and 2D-NMR, MS, UV, and IR). These compounds were evaluated for inhibitory activity on acetylcholinesterase (AChE) and enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC12 cells. |
| PubMedSearch : Wang_2011_Chem.Biodivers_8_1908 |
| PubMedID: 22006719 |
Wang PC, Ran XH, Chen R, Luo HR, Ma QY, Liu YQ, Hu JM, Huang SZ, Jiang HZ, Chen ZQ, Zhou J, Zhao YX (2011)
Sesquiterpenoids and lignans from the roots of Valeriana officinalis L
Chem Biodivers
8 :1908
Wang PC, Ran XH, Chen R, Luo HR, Ma QY, Liu YQ, Hu JM, Huang SZ, Jiang HZ, Chen ZQ, Zhou J, Zhao YX (2011)
Chem Biodivers
8 :1908