| Title : A Fluorogenic Probe with Aggregation-Induced Emission Characteristics for Carboxylesterase Assay through Formation of Supramolecular Microfibers - Wang_2014_Chem.Asian.J_9_784 |
| Author(s) : Wang X , Liu H , Li J , Ding K , Lv Z , Yang Y , Chen H , Li X |
| Ref : Chem Asian J , 9 :784 , 2014 |
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Abstract :
Herein, we report a novel fluorescent "light-up" probe useful for carboxylesterase assay that is based on a tetraphenylethylene derivative containing carboxylic ester groups. The specific cleavage of the carboxylic ester bonds by carboxylesterase results in the generation of a relatively hydrophobic moiety that self-assembles into supramolecular microfibers, thus giving rise to "turn-on" fluorescent signals. A high sensitivity towards carboxylesterase was achieved with a detection limit as low as 29 pM, which is much lower than the corresponding assays based on other fluorescent approaches. |
| PubMedSearch : Wang_2014_Chem.Asian.J_9_784 |
| PubMedID: 24403215 |
Wang X, Liu H, Li J, Ding K, Lv Z, Yang Y, Chen H, Li X (2014)
A Fluorogenic Probe with Aggregation-Induced Emission Characteristics for Carboxylesterase Assay through Formation of Supramolecular Microfibers
Chem Asian J
9 :784
Wang X, Liu H, Li J, Ding K, Lv Z, Yang Y, Chen H, Li X (2014)
Chem Asian J
9 :784