Title : Two new 2-(2-Hydroxy-2-phenylethyl)chromens from agarwood originating from Aquilaria crassna - Wang_2017_J.Asian.Nat.Prod.Res__1 |
Author(s) : Wang HN , Mei WL , Dong WH , Kong FD , Li W , Yuan JZ , Dai HF |
Ref : J Asian Nat Prod Res , :1 , 2017 |
Abstract :
Two new 2-(2-hydroxy-2-phenylethyl)chromones (12), along with three known 2-(2-phenylethyl)chromones (35), were isolated from the agarwood originating from Aquilaria crassna Pierre ex Lecomte. Their structures were determined by the spectroscopic methods including 1D and 2D NMR analysis and comparison with reported data in the literature. All the compounds were isolated from agarwood of A. crassna for the first time. Compounds 1 and 2 exhibited inhibitory activity against acetylcholinesterase (AChE) with 17.4 +/- 0.6 and 15.8 +/- 0.7%, respectively, at a concentration of 50 mug/ml. Besides, Compound 3 expressed antibacterial activities against Ralstonia solanacearum with diameter of the inhibition zone of 6.80 +/- 0.08 mm at a concentration of 10 mg/ml. |
PubMedSearch : Wang_2017_J.Asian.Nat.Prod.Res__1 |
PubMedID: 28984476 |
Wang HN, Mei WL, Dong WH, Kong FD, Li W, Yuan JZ, Dai HF (2017)
Two new 2-(2-Hydroxy-2-phenylethyl)chromens from agarwood originating from Aquilaria crassna
J Asian Nat Prod Res
:1
Wang HN, Mei WL, Dong WH, Kong FD, Li W, Yuan JZ, Dai HF (2017)
J Asian Nat Prod Res
:1