Title : Visualization of carboxylesterase 2 with a near-infrared two-photon fluorescent probe and potential evaluation of its anticancer drug effects in an orthotopic colon carcinoma mice model - Wang_2020_Chem.Commun.(Camb)_56_4412 |
Author(s) : Wang Y , Yu F , Luo X , Li M , Zhao L |
Ref : Chem Commun (Camb) , 56 :4412 , 2020 |
Abstract :
We establish a near-infrared two-photon fluorescent probe for the detection of CE2 with high selectivity and sensitivity. This probe exhibits low cytotoxicity and superior tissue penetration ability for evaluating the real-time activity of CE2 in living cells, in cancer tissues, and in a colon carcinoma mice model. |
PubMedSearch : Wang_2020_Chem.Commun.(Camb)_56_4412 |
PubMedID: 32186556 |
Substrate | DCM-CES2 |
Wang Y, Yu F, Luo X, Li M, Zhao L (2020)
Visualization of carboxylesterase 2 with a near-infrared two-photon fluorescent probe and potential evaluation of its anticancer drug effects in an orthotopic colon carcinoma mice model
Chem Commun (Camb)
56 :4412
Wang Y, Yu F, Luo X, Li M, Zhao L (2020)
Chem Commun (Camb)
56 :4412