| Title : Solvent-Free Enzymatic Synthesis of Ethyl 3-Oxobutyrate Derivative: Characterization and Optimization of Reaction Condition - Wang_2024_Appl.Biochem.Biotechnol__ |
| Author(s) : Wang Y , Chen LM , Liao XQ , Zhang GH , Zhang J |
| Ref : Appl Biochem Biotechnol , : , 2024 |
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Abstract :
It was first found that porcine pancreatic lipase (PPL) could catalyze the Knoevenagel condensation of aromatic aldehydes and ethyl acetoacetate under solvent-free conditions in this paper. Under solvent-free conditions, the highest yield of PPL catalytic reaction was 99.38%, and the Z/E selectivity of the product was 3.93. In addition, the reaction conditions were optimized, and the factors affecting the product structure were studied. |
| PubMedSearch : Wang_2024_Appl.Biochem.Biotechnol__ |
| PubMedID: 38874842 |
Wang Y, Chen LM, Liao XQ, Zhang GH, Zhang J (2024)
Solvent-Free Enzymatic Synthesis of Ethyl 3-Oxobutyrate Derivative: Characterization and Optimization of Reaction Condition
Appl Biochem Biotechnol
:
Wang Y, Chen LM, Liao XQ, Zhang GH, Zhang J (2024)
Appl Biochem Biotechnol
: