| Title : Euphorfinoids E-L: Diterpenoids from the roots of Euphorbia fischeriana with acetylcholinesterase inhibitory activity - Wei_2021_Phytochemistry_190_112867 |
| Author(s) : Wei JC , Zhang XY , Gao YN , Wang DD , He XL , Gao XX , Hu GS , Wang AH , Jia JM |
| Ref : Phytochemistry , 190 :112867 , 2021 |
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Abstract :
Eight undescribed diterpenoids, euphorfinoids E-L, together with twelve known analogues, were isolated from the roots of wild Euphorbia fischeriana. Their structures and absolute configurations were elucidated by a combination of NMR, MS, ECD, and X-ray diffraction analyses. The plausible biosynthetic pathway of 1 was also proposed. The isolated compounds displayed moderate inhibitory activity against acetylcholinesterase (AChE) with 50% inhibiting concentration (IC(50)) values of 6.23-192.38 microM. |
| PubMedSearch : Wei_2021_Phytochemistry_190_112867 |
| PubMedID: 34304117 |
Wei JC, Zhang XY, Gao YN, Wang DD, He XL, Gao XX, Hu GS, Wang AH, Jia JM (2021)
Euphorfinoids E-L: Diterpenoids from the roots of Euphorbia fischeriana with acetylcholinesterase inhibitory activity
Phytochemistry
190 :112867
Wei JC, Zhang XY, Gao YN, Wang DD, He XL, Gao XX, Hu GS, Wang AH, Jia JM (2021)
Phytochemistry
190 :112867