| Title : Characterization of an Enterobacter cloacae Strain Producing both KPC and NDM Carbapenemases by Whole-Genome Sequencing - Wu_2015_Antimicrob.Agents.Chemother_59_6625 |
| Author(s) : Wu W , Feng Y , Carattoli A , Zong Z |
| Ref : Antimicrobial Agents & Chemotherapy , 59 :6625 , 2015 |
|
Abstract :
A carbapenem-resistant Enterobacter cloacae strain, WCHECl-14653, causing a fatal bloodstream infection, was characterized by genome sequencing and conjugation experiments. The strain carried two carbapenemase genes, blaNDM-1 and blaKPC-2, on separate IncF plasmids. The coexistence of blaNDM-1 and blaKPC-2 conferred slightly higher-level carbapenem resistance compared with that of blaNDM-1 or blaKPC-2 alone, and the coexistence of two IncF plasmids may generate new platforms for spreading carbapenemase genes. |
| PubMedSearch : Wu_2015_Antimicrob.Agents.Chemother_59_6625 |
| PubMedID: 26248381 |
| Gene_locus related to this paper: entcl-a0a0k0npw0 |
| Gene_locus | entcl-a0a0k0npw0 |
Wu W, Feng Y, Carattoli A, Zong Z (2015)
Characterization of an Enterobacter cloacae Strain Producing both KPC and NDM Carbapenemases by Whole-Genome Sequencing
Antimicrobial Agents & Chemotherapy
59 :6625
Wu W, Feng Y, Carattoli A, Zong Z (2015)
Antimicrobial Agents & Chemotherapy
59 :6625