| Title : Oxidase-Like Fe-N-C Single-Atom Nanozymes for the Detection of Acetylcholinesterase Activity - Wu_2019_Small__e1903108 |
| Author(s) : Wu Y , Jiao L , Luo X , Xu W , Wei X , Wang H , Yan H , Gu W , Xu BZ , Du D , Lin Y , Zhu C |
| Ref : Small , :e1903108 , 2019 |
|
Abstract :
Single-atom catalysts (SACs) have attracted extensive attention in the catalysis field because of their remarkable catalytic activity, gratifying stability, excellent selectivity, and 100% atom utilization. With atomically dispersed metal active sites, Fe-N-C SACs can mimic oxidase by activating O2 into reactive oxygen species, O2 (-) * radicals. Taking advantages of this property, single-atom nanozymes (SAzymes) can become a great impetus to develop novel biosensors. Herein, the performance of Fe-N-C SACs as oxidase-like nanozymes is explored. Besides, the Fe-N-C SAzymes are applied in biosensor areas to evaluate the activity of acetylcholinesterase based on the inhibition toward nanozyme activity by thiols. Moreover, this SAzymes-based biosensor is further used for monitoring the amounts of organophosphorus compounds. |
| PubMedSearch : Wu_2019_Small__e1903108 |
| PubMedID: 31482681 |
Wu Y, Jiao L, Luo X, Xu W, Wei X, Wang H, Yan H, Gu W, Xu BZ, Du D, Lin Y, Zhu C (2019)
Oxidase-Like Fe-N-C Single-Atom Nanozymes for the Detection of Acetylcholinesterase Activity
Small
:e1903108
Wu Y, Jiao L, Luo X, Xu W, Wei X, Wang H, Yan H, Gu W, Xu BZ, Du D, Lin Y, Zhu C (2019)
Small
:e1903108