| Title : Wheat germ lipase catalyzed kinetic resolution of secondary alcohols in non-aqueous media - Xia_2009_Biotechnol.Lett_31_83 |
| Author(s) : Xia X , Wang YH , Yang B , Wang X |
| Ref : Biotechnol Lett , 31 :83 , 2009 |
|
Abstract :
The lipase from wheat germ was used for the kinetic resolution of secondary alcohols. It has the opposite enantioselectivity against the Kazlauskas rule and acts as an anti-Kazlauskas catalyst. The effect of initial water activity, organic solvent, acyl donor and temperature were investigated. Wheat germ lipase had a high activity and enantioselectivity only in n-hexane with a high initial water activity (alpha(w) = 0.97), especially with 1-phenylethanol (C 32%, E > 200). Its performance changed little with the chain length of acyl donor and temperature. |
| PubMedSearch : Xia_2009_Biotechnol.Lett_31_83 |
| PubMedID: 18777014 |
Xia X, Wang YH, Yang B, Wang X (2009)
Wheat germ lipase catalyzed kinetic resolution of secondary alcohols in non-aqueous media
Biotechnol Lett
31 :83
Xia X, Wang YH, Yang B, Wang X (2009)
Biotechnol Lett
31 :83