| Title : Peroxidase-mimicking Activity of PCN-222(Fe) for Colorimetric Sensing of Acetylcholinesterase Activity and Inhibition - Xia_2021_Anal.Sci_37_1023 |
| Author(s) : Xia M , Liu T , Zhang Y |
| Ref : Anal Sci , 37 :1023 , 2021 |
|
Abstract :
A colorimetric method for detection of acetylcholinesterase (AChE) activity and inhibition was developed using metal organic frameworks (i.e., PCN-222(Fe)) with peroxidase-like activity. The blue tetramethylbenzidine oxidized by PCN-222(Fe) fades due to the reduction by acetylthiocholine chloride produced from AChE catalysis. The detection method shows a linear range of 0.05 - 10 mU mL(-1) and a detection limit of 0.03 mU mL(-1) AChE. Average recoveries in serum samples varied from 93 to 115% and relative standard deviation (RSD) was lower than 4.9%. |
| PubMedSearch : Xia_2021_Anal.Sci_37_1023 |
| PubMedID: 33071263 |
Xia M, Liu T, Zhang Y (2021)
Peroxidase-mimicking Activity of PCN-222(Fe) for Colorimetric Sensing of Acetylcholinesterase Activity and Inhibition
Anal Sci
37 :1023
Xia M, Liu T, Zhang Y (2021)
Anal Sci
37 :1023