| Title : Asperterpenols A and B, New Sesterterpenoids Isolated from a Mangrove Endophytic Fungus Aspergillus sp. 085242 - Xiao_2013_Org.Lett_15_2522 |
| Author(s) : Xiao Z , Huang H , Shao C , Xia X , Ma L , Huang X , Lu Y , Lin Y , Long Y , She Z |
| Ref : Org Lett , 15 :2522 , 2013 |
|
Abstract :
Asperterpenol A (1) and asperterpenol B (2), two novel sesterterpenoids with an unusual 5/8/6/6 tetracyclic ring skeleton, were isolated from a mangrove endophytic fungus Aspergillus sp. 085242. The structures were elucidated on the basis of spectroscopic methods and the absolute configurations determined by single-crystal X-ray diffraction analysis. Compounds 1 and 2 inhibit acetylcholinesterase with IC50 values of 2.3 and 3.0 muM, respectively. |
| PubMedSearch : Xiao_2013_Org.Lett_15_2522 |
| PubMedID: 23642191 |
Xiao Z, Huang H, Shao C, Xia X, Ma L, Huang X, Lu Y, Lin Y, Long Y, She Z (2013)
Asperterpenols A and B, New Sesterterpenoids Isolated from a Mangrove Endophytic Fungus Aspergillus sp. 085242
Org Lett
15 :2522
Xiao Z, Huang H, Shao C, Xia X, Ma L, Huang X, Lu Y, Lin Y, Long Y, She Z (2013)
Org Lett
15 :2522