| Title : Biocatalytic resolution of glycidyl aryl ethers by Trichosporon loubierii : cell\/substrate ratio influences the optical purity of (R) - epoxides - Xu_2004_Biotechnol.Lett_26_1217 |
| Author(s) : Xu Y , Xu JH , Pan J , Tang YF |
| Ref : Biotechnol Lett , 26 :1217 , 2004 |
|
Abstract :
Glycidyl aryl ethers were resolved by using lyophilized cells of Trichosporon loubierii ECU1040 having epoxide hydrolase activity. The activity and enantioselectivity depended on the structure of the aryl group. Different cell/substrate ratios also influenced the optical purity of remaining substrate. An additional stability test of the whole-cell enzyme suggests that rapid deactivation of the epoxide hydrolase was the potential reason. (R)-Epoxides were prepared in gram amounts with optical purity of 87% - 99% ee. |
| PubMedSearch : Xu_2004_Biotechnol.Lett_26_1217 |
| PubMedID: 15289677 |
Xu Y, Xu JH, Pan J, Tang YF (2004)
Biocatalytic resolution of glycidyl aryl ethers by Trichosporon loubierii : cell\/substrate ratio influences the optical purity of (R) - epoxides
Biotechnol Lett
26 :1217
Xu Y, Xu JH, Pan J, Tang YF (2004)
Biotechnol Lett
26 :1217