| Title : Polyphenolic acetylcholinesterase inhibitors from Hopea chinensis - Yan_2012_Planta.Med_78_1015 |
| Author(s) : Yan T , Wang T , Wei W , Jiang N , Qin YH , Tan RX , Ge HM |
| Ref : Planta Med , 78 :1015 , 2012 |
|
Abstract :
Bioassay-guided investigation of the stem bark of Hopea chinensis led to the isolation of two new polyphenols, hopeachinols C(1) and D(2), together with ten known compounds (3-12). Compounds 1 and 2 were determined by extensive analysis of spectroscopic data and computational methods. All of these phytochemicals were tested for acetylcholinesterase inhibitory activity, and five resveratrol-derived compounds (1 and 7-10) exhibited significant activity with their IC(5)(0) values ranging from 4.81 to 11.71 microM. |
| PubMedSearch : Yan_2012_Planta.Med_78_1015 |
| PubMedID: 22628156 |
| Inhibitor | Hopeahainol-A |
Yan T, Wang T, Wei W, Jiang N, Qin YH, Tan RX, Ge HM (2012)
Polyphenolic acetylcholinesterase inhibitors from Hopea chinensis
Planta Med
78 :1015
Yan T, Wang T, Wei W, Jiang N, Qin YH, Tan RX, Ge HM (2012)
Planta Med
78 :1015