| Title : Donepezil and flight simulator performance: effects on retention of complex skills - Yesavage_2002_Neurology_59_123 |
| Author(s) : Yesavage JA , Mumenthaler MS , Taylor JL , Friedman L , O'Hara R , Sheikh J , Tinklenberg J , Whitehouse PJ |
| Ref : Neurology , 59 :123 , 2002 |
|
Abstract :
We report a randomized, double-blind, parallel group, placebo-controlled study to test the effects of the acetylcholinesterase inhibitor, donepezil (5 mg/d for 30 days), on aircraft pilot performance in 18 licensed pilots with mean age of 52 years. After 30 days of treatment, the donepezil group showed greater ability to retain the capacity to perform a set of complex simulator tasks than the placebo group, p < 0.05. Donepezil appears to have beneficial effects on retention of training on complex aviation tasks in nondemented older adults. |
| PubMedSearch : Yesavage_2002_Neurology_59_123 |
| PubMedID: 12105320 |
Yesavage JA, Mumenthaler MS, Taylor JL, Friedman L, O'Hara R, Sheikh J, Tinklenberg J, Whitehouse PJ (2002)
Donepezil and flight simulator performance: effects on retention of complex skills
Neurology
59 :123
Yesavage JA, Mumenthaler MS, Taylor JL, Friedman L, O'Hara R, Sheikh J, Tinklenberg J, Whitehouse PJ (2002)
Neurology
59 :123