Title : Isoterreulactone A, a novel meroterpenoid with anti-acetylcholinesterase activity produced by Aspergillus terreus - Yoo_2005_Bioorg.Med.Chem.Lett_15_353 |
Author(s) : Yoo ID , Cho KM , Lee CK , Kim WG |
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :353 , 2005 |
Abstract :
A new seven-membered lactone type meroterpenoid, isoterreulactone A, was isolated from the solid state fermentation of Aspergillus terreus and its structure was established by various spectral analysis. Isoterreulactone A inhibited acetylcholinesterase with an IC(50) value of 2.5 microM while did not inhibit butyrylcholinesterase even at 500 microM. |
PubMedSearch : Yoo_2005_Bioorg.Med.Chem.Lett_15_353 |
PubMedID: 15603953 |
Yoo ID, Cho KM, Lee CK, Kim WG (2005)
Isoterreulactone A, a novel meroterpenoid with anti-acetylcholinesterase activity produced by Aspergillus terreus
Bioorganic & Medicinal Chemistry Lett
15 :353
Yoo ID, Cho KM, Lee CK, Kim WG (2005)
Bioorganic & Medicinal Chemistry Lett
15 :353