Yoon_2012_Acta.Crystallogr.Sect.E.Struct.Rep.Online_68_o251

Reference

Title : Ethyl 1-[3-(2-oxopyrrolidin-1-yl)prop-yl]-2-phenyl-1H-benzimidazole-5-carboxyl-ate - Yoon_2012_Acta.Crystallogr.Sect.E.Struct.Rep.Online_68_o251
Author(s) : Yoon YK , Ali MA , Choon TS , Asik SI , Razak IA
Ref : Acta Crystallographica Sect E Struct Rep Online , 68 :o251 , 2012
Abstract :

In the title compound, C(23)H(25)N(3)O(3), the benzimidazole ring system is essentially planar [maximum deviation = 0.0240(18)A]. The mean plane through this ring system forms a dihedral angle of 42.23(7) degrees with the benzene ring. The pyrrolidine ring is in an envelope conformation with the flap atom disordered over two sites with occupancies of 0.813(11) and 0.187(11). In the crystal, weak C-H...O hydrogen bonds form R(2) (2)(10) ring motifs, which are connected by further C-H...O inter-actions, forming ribbons along the b axis. The crystal structure is further stabilized by weak Pi-Pi inter-actions involving the imidazole and benzene rings of the benzimidazole ring system [centroid-centroid distances = 3.6788(11) and 3.6316(10)A] and weak C-H...Pi inter-actions.

PubMedSearch : Yoon_2012_Acta.Crystallogr.Sect.E.Struct.Rep.Online_68_o251
PubMedID: 22346899

Related information

Inhibitor CHEMBL3290209

Citations formats

Yoon YK, Ali MA, Choon TS, Asik SI, Razak IA (2012)
Ethyl 1-[3-(2-oxopyrrolidin-1-yl)prop-yl]-2-phenyl-1H-benzimidazole-5-carboxyl-ate
Acta Crystallographica Sect E Struct Rep Online 68 :o251

Yoon YK, Ali MA, Choon TS, Asik SI, Razak IA (2012)
Acta Crystallographica Sect E Struct Rep Online 68 :o251