| Title : Ethyl 1-[3-(2-oxopyrrolidin-1-yl)prop-yl]-2-phenyl-1H-benzimidazole-5-carboxyl-ate - Yoon_2012_Acta.Crystallogr.Sect.E.Struct.Rep.Online_68_o251 |
| Author(s) : Yoon YK , Ali MA , Choon TS , Asik SI , Razak IA |
| Ref : Acta Crystallographica Sect E Struct Rep Online , 68 :o251 , 2012 |
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Abstract :
In the title compound, C(23)H(25)N(3)O(3), the benzimidazole ring system is essentially planar [maximum deviation = 0.0240(18)A]. The mean plane through this ring system forms a dihedral angle of 42.23(7) degrees with the benzene ring. The pyrrolidine ring is in an envelope conformation with the flap atom disordered over two sites with occupancies of 0.813(11) and 0.187(11). In the crystal, weak C-H...O hydrogen bonds form R(2) (2)(10) ring motifs, which are connected by further C-H...O inter-actions, forming ribbons along the b axis. The crystal structure is further stabilized by weak Pi-Pi inter-actions involving the imidazole and benzene rings of the benzimidazole ring system [centroid-centroid distances = 3.6788(11) and 3.6316(10)A] and weak C-H...Pi inter-actions. |
| PubMedSearch : Yoon_2012_Acta.Crystallogr.Sect.E.Struct.Rep.Online_68_o251 |
| PubMedID: 22346899 |
| Inhibitor | CHEMBL3290209 |
Yoon YK, Ali MA, Choon TS, Asik SI, Razak IA (2012)
Ethyl 1-[3-(2-oxopyrrolidin-1-yl)prop-yl]-2-phenyl-1H-benzimidazole-5-carboxyl-ate
Acta Crystallographica Sect E Struct Rep Online
68 :o251
Yoon YK, Ali MA, Choon TS, Asik SI, Razak IA (2012)
Acta Crystallographica Sect E Struct Rep Online
68 :o251