| Title : Functional dissection and module swapping of fungal cyclooligomer depsipeptide synthetases - Yu_2013_Chem.Commun.(Camb)_49_6176 |
| Author(s) : Yu D , Xu F , Gage D , Zhan J |
| Ref : Chem Commun (Camb) , 49 :6176 , 2013 |
|
Abstract :
BbBSLS and BbBEAS were dissected and reconstituted in Saccharomyces cerevisiae. The intermodular linker is essential for the reconstitution of the separate modules. Module 1 can be swapped between BbBEAS and BbBSLS, while modules 2 and 3 control the product profiles. BbBSLS is a flexible enzyme that also synthesizes beauvericins. |
| PubMedSearch : Yu_2013_Chem.Commun.(Camb)_49_6176 |
| PubMedID: 23727842 |
| Gene_locus_frgt | beab2-bsls beaba-bsls |
Yu D, Xu F, Gage D, Zhan J (2013)
Functional dissection and module swapping of fungal cyclooligomer depsipeptide synthetases
Chem Commun (Camb)
49 :6176
Yu D, Xu F, Gage D, Zhan J (2013)
Chem Commun (Camb)
49 :6176