| Title : [The pharmacological correction of the immune homeostasis disorders in acute dichloroethane poisoning] - Zabrodskii_1999_Eksp.Klin.Farmakol_62_35 |
| Author(s) : Zabrodskii PF , Gryzunov AV |
| Ref : Eksperimentalnaia i Klinicheskaia Farmakologiia , 62 :35 , 1999 |
| Abstract : Experiments on Wistar rats and noninbred mice showed that dipyroxim (10 mg/kg administered 3 times per 24 h) and thymogen (10 mg/kg daily for 3 days) restore the reduced under the effect of acute dichlorethane poisoning in a dose of 0.75 LD50 the organism's anti-infectious unspecific resistance and the main humoral and cell immune reactions. Summing of the effects of the drugs under study was encountered in the case of the T-dependent humoral immune response. The effect of dipyroxim was due to restoration of alpha-naphthyl-AS-acetatesterase of immunocytes and, possibly, other types of esterases of T-cells, macrophages, and monocytes. |
| ESTHER : Zabrodskii_1999_Eksp.Klin.Farmakol_62_35 |
| PubMedSearch : Zabrodskii_1999_Eksp.Klin.Farmakol_62_35 |
| PubMedID: 10572750 |
Zabrodskii PF, Gryzunov AV (1999)
[The pharmacological correction of the immune homeostasis disorders in acute dichloroethane poisoning]
Eksperimentalnaia i Klinicheskaia Farmakologiia
62 :35
Zabrodskii PF, Gryzunov AV (1999)
Eksperimentalnaia i Klinicheskaia Farmakologiia
62 :35