Title : Paeonone A, a novel nonanortriterpenoid from the roots of Paeonia lactiflora - Zhang_2021_Bioorg.Chem_110_104783 |
Author(s) : Zhang JF , Li YC , Song YQ , Xia GY , Xia H , Wang YN , Tian GH , Ge GB , Lin S |
Ref : Bioorg Chem , 110 :104783 , 2021 |
Abstract :
Paeonone A (1), a unique nonanortriterpenoid, and a new octanortriterpenoid, paeonone B (2), were isolated from the roots of Paeonia lactiflora, together with a known analogue, palbinone (3). Paeonone A (1) is the first example of naturally occurring nonanortriterpenoid with a diketo acid group. Extensive NMR and HRESIMS experiments were applied to identify the structures of 1 and 2, and their absolute configurations were solved by single-crystal X-ray diffraction and ECD data. Biological properties of 1-3 were explored against pancreatic lipase and cancer cell lines. |
PubMedSearch : Zhang_2021_Bioorg.Chem_110_104783 |
PubMedID: 33714021 |
Zhang JF, Li YC, Song YQ, Xia GY, Xia H, Wang YN, Tian GH, Ge GB, Lin S (2021)
Paeonone A, a novel nonanortriterpenoid from the roots of Paeonia lactiflora
Bioorg Chem
110 :104783
Zhang JF, Li YC, Song YQ, Xia GY, Xia H, Wang YN, Tian GH, Ge GB, Lin S (2021)
Bioorg Chem
110 :104783