Title : Lycopodium alkaloids from Huperzia goebelii - Zhao_2024_Chem.Biodivers__e202400209 |
Author(s) : Zhao QS , Gao BB , Jiang S , Li WY , Ou YF |
Ref : Chem Biodivers , :e202400209 , 2024 |
Abstract :
One new fawcettimine-type Lycopodium alkaloidhupertimine F (1), together with five known (2-6) Lycopodium alkaloids were isolated from Huperzia goebelii. The structure of 1 was elucidated by 1D and 2D NMR spectra, HRESIMS, and X-ray diffraction. Structurally, 1 represents the fourth example of Lycopodium alkaloids characterized by a 5/5/5/5/6 pentacyclic ring system with a 1-aza-7-oxabicyclo[2.2.1]heptane moiety. These known compounds 2, 3, 5, and 6 were isolated from H. goebelii for the first time. Compounds 1-6 were evaluated for acetylcholinesterase, butyrylcholinesterase and monoamine oxidase B inhibitory activities in vitro. |
PubMedSearch : Zhao_2024_Chem.Biodivers__e202400209 |
PubMedID: 38419385 |
Zhao QS, Gao BB, Jiang S, Li WY, Ou YF (2024)
Lycopodium alkaloids from Huperzia goebelii
Chem Biodivers
:e202400209
Zhao QS, Gao BB, Jiang S, Li WY, Ou YF (2024)
Chem Biodivers
:e202400209