| Title : Synthesis of benzofuran derivatives via rearrangement and their inhibitory activity on acetylcholinesterase - Zhou_2010_Molecules_15_8593 |
| Author(s) : Zhou X , Li M , Wang XB , Wang T , Kong LY |
| Ref : Molecules , 15 :8593 , 2010 |
|
Abstract :
During a synthesis of coumarins to obtain new candidates for treating Alzheimer's Disease (AD), an unusual rearrangement of a benzopyran group to a benzofuran group occurred, offering a novel synthesis pathway of these benzofuran derivatives. The possible mechanism of the novel rearrangement was also discussed. All of the benzofuran derivatives have weak anti-AChE activities compared with the reference compound, donepezil. |
| PubMedSearch : Zhou_2010_Molecules_15_8593 |
| PubMedID: 21116228 |
Zhou X, Li M, Wang XB, Wang T, Kong LY (2010)
Synthesis of benzofuran derivatives via rearrangement and their inhibitory activity on acetylcholinesterase
Molecules
15 :8593
Zhou X, Li M, Wang XB, Wang T, Kong LY (2010)
Molecules
15 :8593