Zhou_2020_Eur.J.Med.Chem_200_112415

Reference

Title : Simple analogues of natural product chelerythrine: Discovery of a novel anticholinesterase 2-phenylisoquinolin-2-ium scaffold with excellent potency against acetylcholinesterase - Zhou_2020_Eur.J.Med.Chem_200_112415
Author(s) : Zhou B , Li H , Cui Z , Li D , Geng H , Gao J , Zhou L
Ref : Eur Journal of Medicinal Chemistry , 200 :112415 , 2020
Abstract : As simple analogues of the natural compound chelerythrine, a novel anti-cholinesterase 2-phenylisoquinolin-2-ium scaffold was designed by structure imitation. The activity evaluation led to the discovery of seven compounds with potent anti-acetylcholinesterase activity with IC50 values of
ESTHER : Zhou_2020_Eur.J.Med.Chem_200_112415
PubMedSearch : Zhou_2020_Eur.J.Med.Chem_200_112415
PubMedID: 32454229

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Citations formats

Zhou B, Li H, Cui Z, Li D, Geng H, Gao J, Zhou L (2020)
Simple analogues of natural product chelerythrine: Discovery of a novel anticholinesterase 2-phenylisoquinolin-2-ium scaffold with excellent potency against acetylcholinesterase
Eur Journal of Medicinal Chemistry 200 :112415

Zhou B, Li H, Cui Z, Li D, Geng H, Gao J, Zhou L (2020)
Eur Journal of Medicinal Chemistry 200 :112415