Title : Two new C18-diterpenoid alkaloids from Aconitum leucostomum Worosch - Zhou_2022_Chem.Biodivers__ |
Author(s) : Zhou X , Yang HB , Luo YY , Xu JB , Liu Y , Gao F , Huang S , Chen L |
Ref : Chem Biodivers , : , 2022 |
Abstract :
Two new lappaconitine-type C18-diterpenoid alkaloids, named as leucostosines C (1) and D (2), together with six known compounds (3-8), were isolated from the roots of Aconitum leucostomum Worosch. Their structures were elucidated by various spectroscopic analyses, including IR, HR-ESI-MS, NMR spectra and X-ray experiments. Leucostosine C is the first diterpenoid alkaloid bearing the 7-amino group. The isolated compounds were tested for the acetylcholinesterase (AChE) inhibitory effect and neuroprotective activity, none of them showed significant activities. |
PubMedSearch : Zhou_2022_Chem.Biodivers__ |
PubMedID: 36094326 |
Zhou X, Yang HB, Luo YY, Xu JB, Liu Y, Gao F, Huang S, Chen L (2022)
Two new C18-diterpenoid alkaloids from Aconitum leucostomum Worosch
Chem Biodivers
:
Zhou X, Yang HB, Luo YY, Xu JB, Liu Y, Gao F, Huang S, Chen L (2022)
Chem Biodivers
: