Title : [The reversible inhibition of cholinesterases from different biological sources by phosphonium betaines] - Zhuzhovskii_1996_Zh.Evol.Biokhim.Fiziol_32_212 |
Author(s) : Zhuzhovskii Iu G , Kuznetsova LP , Sochilina EE , Dmitrieva EN , Gololobov Iu G , Bykovskaia E |
Ref : Zhurnal Evoliutsionnoi Biokhimii i Fiziologii , 32 :212 , 1996 |
Abstract :
The action of some phosphonium betains on cholinesterases from different biological sources has been studied. It has been shown, that all studied betains are reversible inhibitors of cholinesterase hydrolysis of acetyltiocholine. Inhibiting action of these compounds on acetylcholinesterases is about ten times weaker that of the majority of known phosphonium salts, while their action on butyrylcholinesterases has no peculiarities. There were found certain differences for each betain compounds in their action on cholinesterases from different biological sources. These results may be used for detail classification of cholinesterases and allow to extend knowledge in comparative enzymology. |
PubMedSearch : Zhuzhovskii_1996_Zh.Evol.Biokhim.Fiziol_32_212 |
PubMedID: 8967277 |
Zhuzhovskii Iu G, Kuznetsova LP, Sochilina EE, Dmitrieva EN, Gololobov Iu G, Bykovskaia E (1996)
[The reversible inhibition of cholinesterases from different biological sources by phosphonium betaines]
Zhurnal Evoliutsionnoi Biokhimii i Fiziologii
32 :212
Zhuzhovskii Iu G, Kuznetsova LP, Sochilina EE, Dmitrieva EN, Gololobov Iu G, Bykovskaia E (1996)
Zhurnal Evoliutsionnoi Biokhimii i Fiziologii
32 :212