| Title : SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL 2-THIO DERIVATIVES OF ATP - Zimmet_1993_Nucleosides.Nucleotides_12_1 |
| Author(s) : Zimmet J , Jarlebark L , Hammarberg T , van Galen PJ , Jacobson KA , Heilbronn E |
| Ref : Nucleosides Nucleotides , 12 :1 , 1993 |
|
Abstract :
2-Alkylthio analogues of adenosine 5'-triphosphate were synthesized and evaluated as P2y purinoceptor agonists. ATP and analogues transiently increased intracellular Ca2+ levels in C6 glioma cells and in skeletal muscle derived myotubes in culture. Most derivatives were resistant to stepwise dephosphorylation by ecto-ATPases. |
| PubMedSearch : Zimmet_1993_Nucleosides.Nucleotides_12_1 |
| PubMedID: 25181577 |
Zimmet J, Jarlebark L, Hammarberg T, van Galen PJ, Jacobson KA, Heilbronn E (1993)
SYNTHESIS AND BIOLOGICAL ACTIVITY OF NOVEL 2-THIO DERIVATIVES OF ATP
Nucleosides Nucleotides
12 :1
Zimmet J, Jarlebark L, Hammarberg T, van Galen PJ, Jacobson KA, Heilbronn E (1993)
Nucleosides Nucleotides
12 :1