Zorn_2026_Efsa.j_24_e10175

The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the genetically modified Trichoderma reesei strain DP-Nzk118 by Genencor International B.V. The genetic modifications do not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism and its DNA. It is intended to be used in the processing of cereals and other grains for the production of distilled alcohol. Since residual amounts of food enzyme-total organic solids are removed in the food manufacturing process, dietary exposure estimation and toxicity testing were considered unnecessary. A search for the homology of the amino acid sequence of the triacylglycerol lipase to known allergens was made and no match was found. The Panel considered that a risk of allergic reactions upon dietary exposure to the food enzyme can be excluded when used for the production of distilled alcohol. Based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.