Wurtman_1978_Hosp.Pract_13_71

Feeding choline, a precursor of the neurotransmitter acetylcholine, has been shown experimentally to increase brain acetylcholine release and enhance cholinergic function A subsequent trial of oral choline ameliorated symptoms in patients with tardive dyskinesia, which has been linked to cholinergic dysfunction. The findings suggest a role for dietary precursors in treating diseases associated with neurotransmitter abnormality.