Title : Using Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autism - Patel_2015_BMC.Bioinformatics_16_186 |
Author(s) : Patel S , Roncaglia P , Lovering RC |
Ref : BMC Bioinformatics , 16 :186 , 2015 |
Abstract :
BACKGROUND: People with an autistic spectrum disorder (ASD) display a variety of characteristic behavioral traits, including impaired social interaction, communication difficulties and repetitive behavior. This complex neurodevelopment disorder is known to be associated with a combination of genetic and environmental factors. Neurexins and neuroligins play a key role in synaptogenesis and neurexin-neuroligin adhesion is one of several processes that have been implicated in autism spectrum disorders. |
PubMedSearch : Patel_2015_BMC.Bioinformatics_16_186 |
PubMedID: 26047810 |
Patel S, Roncaglia P, Lovering RC (2015)
Using Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autism
BMC Bioinformatics
16 :186
Patel S, Roncaglia P, Lovering RC (2015)
BMC Bioinformatics
16 :186