1RWQ

Name : Human Dipeptidyl peptidase IV in complex with 5-aminomethyl-6-(2,4-dichloro-phenyl)-2-(3,5-dimethoxy-phenyl)-pyrimidin-4-amine

Revelation date : 17-Dec-2004

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Hennig, M., Thoma, R., Stihle, M.

Ligand : Inhibitor 5AP Ligand in structure: Ligplot

References (1)

Title : Aminomethylpyrimidines as novel DPP-IV inhibitors: a 10(5)-fold activity increase by optimization of aromatic substituents - Peters_2004_Bioorg.Med.Chem.Lett_14_1491
Author(s) : Peters JU , Weber S , Kritter S , Weiss P , Wallier A , Boehringer M , Hennig M , Kuhn B , Loeffler BM
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1491 , 2004
Abstract :
PubMedSearch : Peters_2004_Bioorg.Med.Chem.Lett_14_1491
PubMedID: 15006388
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 1RWQ Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 1RWQ Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 1RWQ Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 1RWQ 3D, interactive encyclopedia of proteins - PROTEOPEDIA server