Name : Human Dipeptidyl Peptidase IV (DPP4) with piperidine-constrained phenethylamine

Revelation date : 24-Apr-2007

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Pei, Z., Li, X., von Geldern, T. W., Longenecker, K.L., Pireh, D., Stewart, K.D., Backes, B.J., Lai, C., Lubben, T.H., Ballaron, S.J.Beno, D.W., Kempf-Grote, A.J., Sham, H.L., Trevillyan, J.M.

Ligand :

References (1)

Title : Discovery and structure-activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors - Pei_2007_J.Med.Chem_50_1983
Author(s) : Pei Z , Li X , von Geldern TW , Longenecker K , Pireh D , Stewart KD , Backes BJ , Lai C , Lubben TH , Ballaron SJ , Beno DW , Kempf-Grote AJ , Sham HL , Trevillyan JM
Ref : Journal of Medicinal Chemistry , 50 :1983 , 2007
PubMedID: 17367123
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 2OQV Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 2OQV Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 2OQV Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 2OQV 3D, interactive encyclopedia of proteins - PROTEOPEDIA server