Name : A b-aminoacyl containing thiazolidine derivative and DPPIV complex

Revelation date : 16-Mar-2011

Family : DPP4N_Peptidase_S9

Gene_locus : human-DPP4

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Park, W.S., Kang, S.K., Jun, M.A., Shin, M.S., Kim, K.Y., Rhee, S.D., Bae, M.A., Kim, M.S., Kim, K.R., Kang, N.S., Yoo, S.E., Lee, J.O., Song, D.H., Silinski, P., Schneider, S.E., Ahn, J.H., Kim, S.S.

Ligand : Inhibitor beta-aminoacyl-thiazolidine-2da Ligand in structure: Ligplot

References (1)

Title : Discovery of beta-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors - Park_2011_Bioorg.Med.Chem.Lett_21_1366
Author(s) : Park WS , Kang SK , Jun MA , Shin MS , Kim KY , Rhee SD , Bae MA , Kim MS , Kim KR , Kang NS , Yoo SE , Lee JO , Song DH , Silinski P , Schneider SE , Ahn JH , Kim SS
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :1366 , 2011
Abstract :
PubMedSearch : Park_2011_Bioorg.Med.Chem.Lett_21_1366
PubMedID: 21306895
Gene_locus related to this paper: human-DPP4

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 3Q8W Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 3Q8W Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 3Q8W Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 3Q8W 3D, interactive encyclopedia of proteins - PROTEOPEDIA server