4AZ0

Name : Crystal structure of human cathepsin A, complexed with 8a

Revelation date : 26-Sep-2012

Family : Carboxypeptidase_S10

Gene_locus : human-CTSA

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Ruf, S., Buning, C., Schreuder, H., Horstick, G., Linz, W., Olpp, T., Pernerstorfer, J., Hiss, K., Kroll, K., Kannt, A., Kohlmann, M., Linz, D., Hubschle, T., Rutten, H., Wirth, K., Schmidt, T., Sadowski, T

Ligand : Inhibitor CHEMBL3145341 Ligand in structure: Ligplot

References (1)

Title : Novel beta-amino acid derivatives as inhibitors of cathepsin A. - Ruf_2012_J.Med.Chem_55_7636
Author(s) : Ruf S , Buning C , Schreuder H , Horstick G , Linz W , Olpp T , Pernerstorfer J , Hiss K , Kroll K , Kannt A , Kohlmann M , Linz D , Hubschle T , Rutten H , Wirth K , Schmidt T , Sadowski T
Ref : Journal of Medicinal Chemistry , 55 :7636 , 2012
Abstract :
PubMedSearch : Ruf_2012_J.Med.Chem_55_7636
PubMedID: 22861813
Gene_locus related to this paper: human-CTSA

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 4AZ0 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 4AZ0 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 4AZ0 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 4AZ0 3D, interactive encyclopedia of proteins - PROTEOPEDIA server