8RFB

Name : Cryo-EM structure of the R243C mutant of human Prolyl Endopeptidase-Like (PREPL) protein involved in Congenital myasthenic syndrome-22 (CMS22)

Revelation date : 04-Sep-2024

Family : S9N_PREPL_Peptidase_S9

Gene_locus : human-PREPL

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Monnens, Y., Theodoropoulou, A., Rosier, K., Bhalla, K., Mahy, A., Vanhoutte, R., Meulemans, S., Cavani, E., Antanasijevic, A., Lemmens, I., Lee, J.A., Spellicy, C.J., Schroer, R.J., Maselli, R.A., Laverty, C.G., Agostinis, P., Pagliarini, D.J., Verhelst, S., Marcaida, M.J., Rochtus, A., Dal Peraro, M., Creemers, J.W. The reconstructed map of PREPL Arg243C has been deposited to the Electron Microscopy Data Bank (EMDB) with the accession number EMD-19117

Ligand : Ligand in structure: Ligplot