9DRO

Name : FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, fluorophosphonate compound FphB-OX-5 bound

Revelation date : na

Family : 6_AlphaBeta_hydrolase

Gene_locus : staau-SA2367

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Sijie Wang, Emily C. Woods, Jeyun Jo, Jiyun Zhu, Althea Hansel-Harris, Matthew Holcomb, Manuel Llanos, Nichole J. Pedowitz, Tulsi Upadhyay, John Bennett, Matthias Fellner, Ki Wan Park, Anna Zhang, Tulio A. Valdez, Stefano Forli, Alix I Chan, Christian N. Cunningham, Matthew Bogyo

Ligand : Inhibitor FphB-OX-5 Ligand in structure: Ligplot

References (1)

Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2025_J.Am.Chem.Soc__
Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Llanos M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M
Ref : Journal of the American Chemical Society , : , 2025
Abstract :
PubMedSearch : Wang_2025_J.Am.Chem.Soc__
PubMedID: 40013487
Gene_locus related to this paper: staau-MW2456 , staau-SA2367

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 9DRO Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 9DRO Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 9DRO Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 9DRO 3D, interactive encyclopedia of proteins - PROTEOPEDIA server