| Title : Unique structural and ligand binding properties of the Staphylococcus aureus serine hydrolase FphE - Jo_2025_bioRxiv__ |
| Author(s) : Jo J , Upadhyay T , You X , Bennett JM , Lee H , Bogyo M , Fellner M |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Jo_2025_bioRxiv__ |
| PubMedID: 41280051 |
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |
| Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2025_J.Am.Chem.Soc__ |
| Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Llanos M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_J.Am.Chem.Soc__ |
| PubMedID: 40013487 |
| Gene_locus related to this paper: staau-MW2456 , staau-SA2367 |
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |
| Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2025_J.Am.Chem.Soc__ |
| Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Llanos M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_J.Am.Chem.Soc__ |
| PubMedID: 40013487 |
| Gene_locus related to this paper: staau-MW2456 , staau-SA2367 |
| Title : Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation - Upadhyay_2025_Nat.Commun_16_5046 |
| Author(s) : Upadhyay T , Woods EC , Dela Ahator S , Julin K , Faucher FF , Uddin MJ , Hollander MJ , Pedowitz NJ , Abegg D , Hammond I , Eke IE , Wang S , Chen S , Bennett JM , Jo J , Lentz CS , Adibekian A , Fellner M , Bogyo M |
| Ref : Nat Commun , 16 :5046 , 2025 |
| Abstract : |
| PubMedSearch : Upadhyay_2025_Nat.Commun_16_5046 |
| PubMedID: 40447595 |
| Gene_locus related to this paper: staau-MW0741 , staau-SA2367 , staep-SE2095 |
| Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2025_J.Am.Chem.Soc__ |
| Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Llanos M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2025 |
| Abstract : |
| PubMedSearch : Wang_2025_J.Am.Chem.Soc__ |
| PubMedID: 40013487 |
| Gene_locus related to this paper: staau-MW2456 , staau-SA2367 |
| Title : Unique structural and ligand binding properties of the Staphylococcus aureus serine hydrolase FphE - Jo_2025_bioRxiv__ |
| Author(s) : Jo J , Upadhyay T , You X , Bennett JM , Lee H , Bogyo M , Fellner M |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Jo_2025_bioRxiv__ |
| PubMedID: 41280051 |
| Title : Unique structural and ligand binding properties of the Staphylococcus aureus serine hydrolase FphE - Jo_2025_bioRxiv__ |
| Author(s) : Jo J , Upadhyay T , You X , Bennett JM , Lee H , Bogyo M , Fellner M |
| Ref : bioRxiv , : , 2025 |
| Abstract : |
| PubMedSearch : Jo_2025_bioRxiv__ |
| PubMedID: 41280051 |
| Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2024_bioRxiv__ |
| Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M |
| Ref : bioRxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Wang_2024_bioRxiv__ |
| PubMedID: 39574702 |
| Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2024_bioRxiv__ |
| Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M |
| Ref : bioRxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Wang_2024_bioRxiv__ |
| PubMedID: 39574702 |
| Title : Similar but Distinct-Biochemical Characterization of the Staphylococcus aureus Serine Hydrolases FphH and FphI - Fellner_2024_Proteins__ |
| Author(s) : Fellner M , Randall G , Bitac I , Warrender AK , Sethi A , Jelinek R , Kass I |
| Ref : Proteins , : , 2024 |
| Abstract : |
| PubMedSearch : Fellner_2024_Proteins__ |
| PubMedID: 39726198 |
| Gene_locus related to this paper: staau-MW0741 , staau-SAV0457 |
| Title : Similar but Distinct-Biochemical Characterization of the Staphylococcus aureus Serine Hydrolases FphH and FphI - Fellner_2024_Proteins__ |
| Author(s) : Fellner M , Randall G , Bitac I , Warrender AK , Sethi A , Jelinek R , Kass I |
| Ref : Proteins , : , 2024 |
| Abstract : |
| PubMedSearch : Fellner_2024_Proteins__ |
| PubMedID: 39726198 |
| Gene_locus related to this paper: staau-MW0741 , staau-SAV0457 |
| Title : Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections - Jo_2024_J.Am.Chem.Soc__ |
| Author(s) : Jo J , Upadhyay T , Woods EC , Park KW , Pedowitz NJ , Jaworek-Korjakowska J , Wang S , Valdez TA , Fellner M , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2024 |
| Abstract : |
| PubMedSearch : Jo_2024_J.Am.Chem.Soc__ |
| PubMedID: 38411555 |
| Gene_locus related to this paper: staau-SA2367 |
| Title : Similar but Distinct-Biochemical Characterization of the Staphylococcus aureus Serine Hydrolases FphH and FphI - Fellner_2024_Proteins__ |
| Author(s) : Fellner M , Randall G , Bitac I , Warrender AK , Sethi A , Jelinek R , Kass I |
| Ref : Proteins , : , 2024 |
| Abstract : |
| PubMedSearch : Fellner_2024_Proteins__ |
| PubMedID: 39726198 |
| Gene_locus related to this paper: staau-MW0741 , staau-SAV0457 |
| Title : Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation - Bogyo_2024_Res.Sq__ |
| Author(s) : Bogyo M , Upadhyay T , Woods E , Ahator S , Julin K , Faucher F , Hollander M , Pedowitz N , Abegg D , Hammond I , Eke I , Wang S , Chen S , Bennett J , Jo J , Lentz C , Adibekian A , Fellner M |
| Ref : Res Sq , : , 2024 |
| Abstract : |
| PubMedSearch : Bogyo_2024_Res.Sq__ |
| PubMedID: 39711551 |
| Title : Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections - Jo_2024_J.Am.Chem.Soc__ |
| Author(s) : Jo J , Upadhyay T , Woods EC , Park KW , Pedowitz NJ , Jaworek-Korjakowska J , Wang S , Valdez TA , Fellner M , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2024 |
| Abstract : |
| PubMedSearch : Jo_2024_J.Am.Chem.Soc__ |
| PubMedID: 38411555 |
| Gene_locus related to this paper: staau-SA2367 |
| Title : Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation - Bogyo_2024_Res.Sq__ |
| Author(s) : Bogyo M , Upadhyay T , Woods E , Ahator S , Julin K , Faucher F , Hollander M , Pedowitz N , Abegg D , Hammond I , Eke I , Wang S , Chen S , Bennett J , Jo J , Lentz C , Adibekian A , Fellner M |
| Ref : Res Sq , : , 2024 |
| Abstract : |
| PubMedSearch : Bogyo_2024_Res.Sq__ |
| PubMedID: 39711551 |
| Title : Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections - Jo_2024_J.Am.Chem.Soc__ |
| Author(s) : Jo J , Upadhyay T , Woods EC , Park KW , Pedowitz NJ , Jaworek-Korjakowska J , Wang S , Valdez TA , Fellner M , Bogyo M |
| Ref : Journal of the American Chemical Society , : , 2024 |
| Abstract : |
| PubMedSearch : Jo_2024_J.Am.Chem.Soc__ |
| PubMedID: 38411555 |
| Gene_locus related to this paper: staau-SA2367 |
| Title : An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor - Wang_2024_bioRxiv__ |
| Author(s) : Wang S , Woods EC , Jo J , Zhu J , Hansel-Harris A , Holcomb M , Pedowitz NJ , Upadhyay T , Bennett J , Fellner M , Park KW , Zhang A , Valdez TA , Forli S , Chan AI , Cunningham CN , Bogyo M |
| Ref : bioRxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Wang_2024_bioRxiv__ |
| PubMedID: 39574702 |
| Title : Covalent-fragment screening identifies selective inhibitors of multiple Staphylococcus aureus serine hydrolases important for growth and biofilm formation - Bogyo_2024_Res.Sq__ |
| Author(s) : Bogyo M , Upadhyay T , Woods E , Ahator S , Julin K , Faucher F , Hollander M , Pedowitz N , Abegg D , Hammond I , Eke I , Wang S , Chen S , Bennett J , Jo J , Lentz C , Adibekian A , Fellner M |
| Ref : Res Sq , : , 2024 |
| Abstract : |
| PubMedSearch : Bogyo_2024_Res.Sq__ |
| PubMedID: 39711551 |
| Title : Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response - Fellner_2023_ACS.Infect.Dis__ |
| Author(s) : Fellner M , Walsh A , Dela Ahator S , Aftab N , Sutherland B , Tan EW , Bakker AT , Martin NI , van der Stelt M , Lentz CS |
| Ref : ACS Infect Dis , : , 2023 |
| Abstract : |
| PubMedSearch : Fellner_2023_ACS.Infect.Dis__ |
| PubMedID: 37824340 |
| Gene_locus related to this paper: staau-MW0741 |
| Title : Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response - Fellner_2023_ACS.Infect.Dis__ |
| Author(s) : Fellner M , Walsh A , Dela Ahator S , Aftab N , Sutherland B , Tan EW , Bakker AT , Martin NI , van der Stelt M , Lentz CS |
| Ref : ACS Infect Dis , : , 2023 |
| Abstract : |
| PubMedSearch : Fellner_2023_ACS.Infect.Dis__ |
| PubMedID: 37824340 |
| Gene_locus related to this paper: staau-MW0741 |
| Title : Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response - Fellner_2023_ACS.Infect.Dis__ |
| Author(s) : Fellner M , Walsh A , Dela Ahator S , Aftab N , Sutherland B , Tan EW , Bakker AT , Martin NI , van der Stelt M , Lentz CS |
| Ref : ACS Infect Dis , : , 2023 |
| Abstract : |
| PubMedSearch : Fellner_2023_ACS.Infect.Dis__ |
| PubMedID: 37824340 |
| Gene_locus related to this paper: staau-MW0741 |
| Title : Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets - Fellner_2022_ADMET.DMPK_10_107 |
| Author(s) : Fellner M |
| Ref : ADMET & DMPK , 10 :107 , 2022 |
| Abstract : |
| PubMedSearch : Fellner_2022_ADMET.DMPK_10_107 |
| PubMedID: 35350120 |
| Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188 |
| Title : Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets - Fellner_2022_ADMET.DMPK_10_107 |
| Author(s) : Fellner M |
| Ref : ADMET & DMPK , 10 :107 , 2022 |
| Abstract : |
| PubMedSearch : Fellner_2022_ADMET.DMPK_10_107 |
| PubMedID: 35350120 |
| Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188 |
| Title : Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets - Fellner_2022_ADMET.DMPK_10_107 |
| Author(s) : Fellner M |
| Ref : ADMET & DMPK , 10 :107 , 2022 |
| Abstract : |
| PubMedSearch : Fellner_2022_ADMET.DMPK_10_107 |
| PubMedID: 35350120 |
| Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188 |
| Title : Identification of highly selective covalent inhibitors by phage display - Chen_2021_Nat.Biotechnol_39_490 |
| Author(s) : Chen S , Lovell S , Lee S , Fellner M , Mace PD , Bogyo M |
| Ref : Nat Biotechnol , 39 :490 , 2021 |
| Abstract : |
| PubMedSearch : Chen_2021_Nat.Biotechnol_39_490 |
| PubMedID: 33199876 |
| Gene_locus related to this paper: staau-SA2422 |
| Title : Identification of highly selective covalent inhibitors by phage display - Chen_2021_Nat.Biotechnol_39_490 |
| Author(s) : Chen S , Lovell S , Lee S , Fellner M , Mace PD , Bogyo M |
| Ref : Nat Biotechnol , 39 :490 , 2021 |
| Abstract : |
| PubMedSearch : Chen_2021_Nat.Biotechnol_39_490 |
| PubMedID: 33199876 |
| Gene_locus related to this paper: staau-SA2422 |
| Title : Identification of highly selective covalent inhibitors by phage display - Chen_2021_Nat.Biotechnol_39_490 |
| Author(s) : Chen S , Lovell S , Lee S , Fellner M , Mace PD , Bogyo M |
| Ref : Nat Biotechnol , 39 :490 , 2021 |
| Abstract : |
| PubMedSearch : Chen_2021_Nat.Biotechnol_39_490 |
| PubMedID: 33199876 |
| Gene_locus related to this paper: staau-SA2422 |
| Title : Structural basis for the inhibitor and substrate specificity of the unique Fph serine hydrolases of Staphylococcus aureus - Fellner_2020_ACS.Infect.Dis_6_2771 |
| Author(s) : Fellner M , Lentz CS , Jamieson SA , Brewster JL , Chen L , Bogyo M , Mace PD |
| Ref : ACS Infect Dis , 6 :2771 , 2020 |
| Abstract : |
| PubMedSearch : Fellner_2020_ACS.Infect.Dis_6_2771 |
| PubMedID: 32865965 |
| Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188 |
| Title : Structural basis for the inhibitor and substrate specificity of the unique Fph serine hydrolases of Staphylococcus aureus - Fellner_2020_ACS.Infect.Dis_6_2771 |
| Author(s) : Fellner M , Lentz CS , Jamieson SA , Brewster JL , Chen L , Bogyo M , Mace PD |
| Ref : ACS Infect Dis , 6 :2771 , 2020 |
| Abstract : |
| PubMedSearch : Fellner_2020_ACS.Infect.Dis_6_2771 |
| PubMedID: 32865965 |
| Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188 |
| Title : Structural basis for the inhibitor and substrate specificity of the unique Fph serine hydrolases of Staphylococcus aureus - Fellner_2020_ACS.Infect.Dis_6_2771 |
| Author(s) : Fellner M , Lentz CS , Jamieson SA , Brewster JL , Chen L , Bogyo M , Mace PD |
| Ref : ACS Infect Dis , 6 :2771 , 2020 |
| Abstract : |
| PubMedSearch : Fellner_2020_ACS.Infect.Dis_6_2771 |
| PubMedID: 32865965 |
| Gene_locus related to this paper: staau-MW0741 , staau-MW2456 , staau-SA1143 , staau-SA2240 , staau-SA2306 , staau-SA2367 , staau-SA2422 , staau-SAV0457 , staau-SAV1793 , staau-SAV2188 |