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Structure Report for: 7XN1

Name|Crystal structure of human acetylcholinesterase in complex with tacrine (replace 7E3I)
Revelation date|01-Mar-2023
Family|ACHE: there are 545 genes in this family, 315 structure(s)
Gene_locus|human-ACHE
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Dileep, K.V.,Ihara, K.,Mishima-Tsumagari, C.,Kukimoto-Niino, M.,Yonemochi, M.,Hanada, K.,Shirouzu, M.,Zhang, K.Y.J.
Ligand|Inhibitor: Tacrine Ligand in structure: Ligplot


Reference

    Title: Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery
    Dileep KV, Ihara K, Mishima-Tsumagari C, Kukimoto-Niino M, Yonemochi M, Hanada K, Shirouzu M, Zhang KYJ
    Ref: Int J Biol Macromol, 210:172, 2022 : PubMed

            



Representative scheme of ACHE structure and an image from PDBsum server



Databases

PDB-Sum7XN1 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7XN1 Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7XN1 Structural Classification Of Protein - SCOP server
PROTEOPEDIA7xn1 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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