DCNC7
120-fold NIR fluorescence enhancement upon the BuChE reaction, with fast kinetics (15 min), high sensitivity (detection limit 0.0206 U/L)
General
Type : Fluorescent Probe, Near-Infrared fluorescent Probe, Trifluoro, Carboxylate, Cyanide, Cyclopropyl
Chemical_Nomenclature : 4-[(1E)-2-(3-dicyanomethylidene-5,5-dimethylcyclohex-1-en-1-yl)ethenyl]-2-(trifluoromethyl)phenyl cyclopropanecarboxylate
Canonical SMILES : C1C(CC(=CC1=C(C#N)C#N)C=CC2=CC=C(C(=C2)C(F)(F)F)OC(=O)C3CC3)(C)C
InChI : InChI=1S\/C24H21F3N2O2\/c1-23(2)11-16(9-18(12-23)19(13-28)14-29)4-3-15-5-8-21(20(10-15)24(25,26)27)31-22(30)17-6-7-17\/h3-5,8-10,17H,6-7,11-12H2,1-2H3
InChIKey : DCDBFGOCWWZAGY-UHFFFAOYSA-N
Other name(s) : 4-[(E)-[9,10-Diazanylidyne-5,5-dimethyl-m-mentha-1,3(8)-dien-7-ylidene]methyl]-2-(trifluoromethyl)phenyl cyclopropanecarboxylate
Target
Structures : No structure
Families : No family
References (1)
| Title : Rational design of halogen-substituted near-infrared fluorescent probes for butyrylcholinesterase: from drug screening to imaging and therapeutic evaluation in Alzheimer's disease - Jiang_2026_Biosens.Bioelectron_313_119140 |
| Author(s) : Jiang L , Yan J , Liu C , Dong X , Shi R , Ma Q , Sun S , Sun Y |
| Ref : Biosensors & Bioelectronics , 313 :119140 , 2026 |
| Abstract : |
| PubMedSearch : Jiang_2026_Biosens.Bioelectron_313_119140 |
| PubMedID: 42632212 |