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Cyanide

Chemical compounds that contains a CN functional group. Organic cyanides are usually called nitriles. Cyanogenesis is a defense process of several thousand plant species. (Some millipedes are able to exude toxic hydrogen cyanide as a defense). Hydroxynitrile lyase, a key enzyme of this process, cleaves a cyanohydrin into hydrocyanic acid and the corresponding aldehyde or ketone. The reverse reaction constitutes an important tool in biocatalysis. Building block for many inhibitors of enzymes
Substrate Main targeted enzyme familyes Type Structure
Hemicyanine-dye Hexanoate Polymethine Cyanide Dye
NCES Carb_B_Chordata Fluorescent Probe Near-Infrared fluorescent Probe Cyanide Coumarin
Cypermethrin Carb_B_Arthropoda LYsophospholipase_carboxylesterase Carb_B_Chordata 6_AlphaBeta_hydrolase pyrethroid Insecticide Phenoxyphenyl Cyclopropane Not A\/B H target Cyanide
DCM-CES2 Carb_B_Chordata Cyanide Fluorescent Probe Near-Infrared fluorescent Probe Chromen
CEL-CES2 Cyanide Fluorescent Probe Adamantyl Dioxetane
DXMB Carb_B_Chordata Fluorescent Probe Benzoate Cyanide Xanthene
IPAN BCHE ACHE Cyanide Fluorescent Probe Near-Infrared fluorescent Probe
Cyanide-ion Hydroxynitrile_lyase Cyanide
Cyflumetofen Cholinesterase-like Acaricide Cyanide Propionate Not A\/B H target
Fenpropathrin Carb_B_Arthropoda Cholinesterase-like pyrethroid Insecticide Acaricide Cyanide Not A\/B H target Phenoxyphenyl Cyclopropane
CNDE Lipase_3 Cyanide
4-hydroxymandelonitrile Hydroxynitrile_lyase Cyanide
Mandelonitrile Hydroxynitrile_lyase Cyanide Benzaldehyde
2,3-dimethyl-2-hydroxy-butyronitrile Hydroxynitrile_lyase Cyanide
lambda-Cyhalothrin Carb_B_Arthropoda CarbLipBact_1 6_AlphaBeta_hydrolase HNLyase_Bact pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropane
Deltamethrin Carboxylesterase Carb_B_Chordata Carb_B_Arthropoda Carb_B_Bacteria 6_AlphaBeta_hydrolase HNLyase_Bact pyrethroid Insecticide Phenoxyphenyl Cyanide Cyclopropane
PHOME Epoxide_hydrolase Fluorescent Probe Epoxide Cyanide Naphthalen
CMNGC Epoxide_hydrolase CFTR-inhibitory-factor_Cif Fluorescent Probe Epoxide Cyanide Naphthalen
TCFB Carb_B_Chordata Fluorescent Probe Cyanide Benzoate
4-Bromobutanenitrile Haloalkane_dehalogenase-HLD1 Haloalkane_dehalogenase-HLD2 Haloalkane Cyanide
Acetonecyanohydrin Hydroxynitrile_lyase Cyanide
2-Cyanoethylacetate ACHE Cyanide Acetate