Gelucire 44/14 is a semi-solid self-emulsifying excipient used for the oral delivery of poorly water-soluble drugs. It is composed of C8-C18 acylglycerols and PEG-32 esters, which are potential substrates for lipases.
Type : complex mix, Polymer, Poly-ethylene-glycol
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Other name(s) : Gelucire 44\/14
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Structures : No structure
Families : Acidic_Lipase
Title : Comparative study on digestive lipase activities on the self emulsifying excipient Labrasol, medium chain glycerides and PEG esters - Fernandez_2007_Biochim.Biophys.Acta_1771_633 |
Author(s) : Fernandez S , Jannin V , Rodier JD , Ritter N , Mahler B , Carriere F |
Ref : Biochimica & Biophysica Acta , 1771 :633 , 2007 |
Abstract : |
PubMedSearch : Fernandez_2007_Biochim.Biophys.Acta_1771_633 |
PubMedID: 17418634 |