Specific aminoacylation of the phospholipid phosphatidylglycerol (PG) with alanine (or with lysine) was shown to render various bacteria less susceptible to antimicrobial agents and environmental stresses
Type : Hexanoate, Alkyl ester, Phosphatidylglycerol
Chemical_Nomenclature : [2,3-dihydroxypropoxy(hydroxy)phosphoryl] (2S)-2,6-diaminohexanoate
Canonical SMILES : C(CCN)CC(C(=O)OP(=O)(O)OCC(CO)O)N
InChI : InChI=1S\/C9H21N2O7P\/c10-4-2-1-3-8(11)9(14)18-19(15,16)17-6-7(13)5-12\/h7-8,12-13H,1-6,10-11H2,(H,15,16)\/t7?,8-\/m0\/s1
InChIKey : FGYYWCMRFGLJOB-MQWKRIRWSA-N
Other name(s) : lysyl-phosphatidylglycerol || (S)-2,6-diaminohexanoic (2,3-dihydroxypropyl phosphoric) anhydride || L-Lysine, monoanhydride with 2,3-dihydroxypropyl dihydrogen phosphate
MW : 300.25
Formula : C9H21N2O7P
CAS_number : 42241-11-2
PubChem : 6451847
UniChem : FGYYWCMRFGLJOB-MQWKRIRWSA-N
Structures : No structure
Families : 6_AlphaBeta_hydrolase
Title : A conserved hydrolase responsible for the cleavage of aminoacylphosphatidylglycerol in the membrane of Enterococcus faecium - Smith_2013_J.Biol.Chem_288_22768 |
Author(s) : Smith AM , Harrison JS , Sprague KM , Roy H |
Ref : Journal of Biological Chemistry , 288 :22768 , 2013 |
Abstract : |
PubMedSearch : Smith_2013_J.Biol.Chem_288_22768 |
PubMedID: 23793054 |
Gene_locus related to this paper: entfc-q3xx25 |