Nitroaspirin
Nitric Oxide-Releasing Acetylsalicylic Acid Derivative is a nitric oxide (NO) donating derivative of acetylsalicylic acid with anti-inflammatory, analgesic, antipyretic, antithrombotic, gastroprotective and potential antitumor activities
General
Chemical_Nomenclature : [3-(nitrooxymethyl)phenyl] 2-acetyloxybenzoate
Canonical SMILES : CC(=O)OC1=CC=CC=C1C(=O)OC2=CC=CC(=C2)CO[N+](=O)[O-]
InChI : InChI=1S\/C16H13NO7\/c1-11(18)23-15-8-3-2-7-14(15)16(19)24-13-6-4-5-12(9-13)10-22-17(20)21\/h2-9H,10H2,1H3
InChIKey : IOJUJUOXKXMJNF-UHFFFAOYSA-N
Other name(s) : Ncx-4016 || NO-Aspirin 1 || Ncx 4016 || SCHEMBL19524 || CHEMBL374385 || CHEBI:125482 || DB12445
MW : 331.28
Formula : C16H13NO7
CAS_number : 175033-36-0
PubChem : 119032
UniChem : IOJUJUOXKXMJNF-UHFFFAOYSA-N
Target
Structures : No structure
Families : BCHE
References (1)
| Title : Evaluation of nitrate-substituted pseudocholine esters of aspirin as potential nitro-aspirins - Gilmer_2007_Bioorg.Med.Chem.Lett_17_3217 |
| Author(s) : Gilmer JF , Moriarty LM , Clancy JM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :3217 , 2007 |
| Abstract : |
| PubMedSearch : Gilmer_2007_Bioorg.Med.Chem.Lett_17_3217 |
| PubMedID: 17376682 |