Octinoxate
Neutralize UV radiation dissipated by sunlight
General
Type : Cinnamate, Sun screen additive
Chemical_Nomenclature : 2-ethylhexyl (E)-3-(4-methoxyphenyl)prop-2-enoate
Canonical SMILES : CCCCC(CC)COC(=O)\/C=C\/C1=CC=C(C=C1)OC
InChI : InChI=1S\/C18H26O3\/c1-4-6-7-15(5-2)14-21-18(19)13-10-16-8-11-17(20-3)12-9-16\/h8-13,15H,4-7,14H2,1-3H3\/b13-10+
InChIKey : YBGZDTIWKVFICR-JLHYYAGUSA-N
Other name(s) : 2-Ethylhexyl p-methoxycinnamate || Parsol MCX || Parsol MOX || Parsol || Octyl methoxycinnamate || 2-Ethylhexyl-p-methoxycinnamate || Escalol 557 || EHMC || RefChem:55743 || SCHEMBL15609 || CHEBI:88667
MW : 290.4
Formula : C18H26O3
CAS_number : 5466-77-3
PubChem : 5355130
UniChem : YBGZDTIWKVFICR-JLHYYAGUSA-N
Target
Structures : No structure
Families : Carb_B_Chordata
References (12)
| Title : Assessing the hepatic metabolism of six sunscreen ultraviolet filters: In vitro-in vivo extrapolation approach using human liver microsomes and hepatic parameter predictions for exposure risk assessment - Baviera_2025_Biochem.Pharmacol__117564 |
| Author(s) : Baviera GS , Poli VR , Oka-Duarte L , Santos Barbetta MF , Moraes de Oliveira AR |
| Ref : Biochemical Pharmacology , :117564 , 2025 |
| Abstract : |
| PubMedSearch : Baviera_2025_Biochem.Pharmacol__117564 |
| PubMedID: 41319926 |
| Title : Assessing the hepatic metabolism of six sunscreen ultraviolet filters: In vitro-in vivo extrapolation approach using human liver microsomes and hepatic parameter predictions for exposure risk assessment - Baviera_2025_Biochem.Pharmacol__117564 |
| Author(s) : Baviera GS , Poli VR , Oka-Duarte L , Santos Barbetta MF , Moraes de Oliveira AR |
| Ref : Biochemical Pharmacology , :117564 , 2025 |
| Abstract : |
| PubMedSearch : Baviera_2025_Biochem.Pharmacol__117564 |
| PubMedID: 41319926 |
| Title : Assessing the hepatic metabolism of six sunscreen ultraviolet filters: In vitro-in vivo extrapolation approach using human liver microsomes and hepatic parameter predictions for exposure risk assessment - Baviera_2025_Biochem.Pharmacol__117564 |
| Author(s) : Baviera GS , Poli VR , Oka-Duarte L , Santos Barbetta MF , Moraes de Oliveira AR |
| Ref : Biochemical Pharmacology , :117564 , 2025 |
| Abstract : |
| PubMedSearch : Baviera_2025_Biochem.Pharmacol__117564 |
| PubMedID: 41319926 |
| Title : In vitro metabolism of sunscreen compounds by liquid chromatography\/high-resolution tandem mass spectrometry - Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| Author(s) : Guesmi A , Ohlund L , Sleno L |
| Ref : Rapid Commun Mass Spectrom , 34 :e8679 , 2020 |
| Abstract : |
| PubMedSearch : Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| PubMedID: 31782973 |
| Title : In vitro metabolism of sunscreen compounds by liquid chromatography\/high-resolution tandem mass spectrometry - Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| Author(s) : Guesmi A , Ohlund L , Sleno L |
| Ref : Rapid Commun Mass Spectrom , 34 :e8679 , 2020 |
| Abstract : |
| PubMedSearch : Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| PubMedID: 31782973 |
| Title : In vitro metabolism of sunscreen compounds by liquid chromatography\/high-resolution tandem mass spectrometry - Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| Author(s) : Guesmi A , Ohlund L , Sleno L |
| Ref : Rapid Commun Mass Spectrom , 34 :e8679 , 2020 |
| Abstract : |
| PubMedSearch : Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| PubMedID: 31782973 |
| Title : Eco-friendly methodology for efficient synthesis and scale-up of 2-ethylhexyl-p-methoxycinnamate using Rhizopus oryzae lipase and its biological evaluation - Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| Author(s) : Kumar V , Jahan F , Kameswaran K , Mahajan RV , Saxena RK |
| Ref : J Ind Microbiol Biotechnol , 41 :907 , 2014 |
| Abstract : |
| PubMedSearch : Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| PubMedID: 24668019 |
| Title : Eco-friendly methodology for efficient synthesis and scale-up of 2-ethylhexyl-p-methoxycinnamate using Rhizopus oryzae lipase and its biological evaluation - Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| Author(s) : Kumar V , Jahan F , Kameswaran K , Mahajan RV , Saxena RK |
| Ref : J Ind Microbiol Biotechnol , 41 :907 , 2014 |
| Abstract : |
| PubMedSearch : Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| PubMedID: 24668019 |
| Title : Eco-friendly methodology for efficient synthesis and scale-up of 2-ethylhexyl-p-methoxycinnamate using Rhizopus oryzae lipase and its biological evaluation - Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| Author(s) : Kumar V , Jahan F , Kameswaran K , Mahajan RV , Saxena RK |
| Ref : J Ind Microbiol Biotechnol , 41 :907 , 2014 |
| Abstract : |
| PubMedSearch : Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| PubMedID: 24668019 |
| Title : A new sunscreen of the cinnamate class: synthesis and enzymatic hydrolysis evaluation of glyceryl esters of p-methoxycinnamic acid - de Freitas_2005_Eur.J.Pharm.Sci_25_67 |
| Author(s) : de Freitas ZM , dos Santos EP , da Rocha JF , Dellamora-Ortiz GM , Goncalves JC |
| Ref : Eur J Pharm Sci , 25 :67 , 2005 |
| Abstract : |
| PubMedSearch : de Freitas_2005_Eur.J.Pharm.Sci_25_67 |
| PubMedID: 15854802 |
| Title : A new sunscreen of the cinnamate class: synthesis and enzymatic hydrolysis evaluation of glyceryl esters of p-methoxycinnamic acid - de Freitas_2005_Eur.J.Pharm.Sci_25_67 |
| Author(s) : de Freitas ZM , dos Santos EP , da Rocha JF , Dellamora-Ortiz GM , Goncalves JC |
| Ref : Eur J Pharm Sci , 25 :67 , 2005 |
| Abstract : |
| PubMedSearch : de Freitas_2005_Eur.J.Pharm.Sci_25_67 |
| PubMedID: 15854802 |
| Title : A new sunscreen of the cinnamate class: synthesis and enzymatic hydrolysis evaluation of glyceryl esters of p-methoxycinnamic acid - de Freitas_2005_Eur.J.Pharm.Sci_25_67 |
| Author(s) : de Freitas ZM , dos Santos EP , da Rocha JF , Dellamora-Ortiz GM , Goncalves JC |
| Ref : Eur J Pharm Sci , 25 :67 , 2005 |
| Abstract : |
| PubMedSearch : de Freitas_2005_Eur.J.Pharm.Sci_25_67 |
| PubMedID: 15854802 |