Octisalate
neutralize UV radiation dissipated by sunlight || Neutralize UV radiation dissipated by sunlight. CES2 is exclusively responsible for the biotransformation of homosalate
General
Type : Sun screen additive, Salicylic, Aryl ester
Chemical_Nomenclature : 2-ethylhexyl 2-hydroxybenzoate
Canonical SMILES : CCCCC(CC)COC(=O)C1=CC=CC=C1O
InChI : InChI=1S\/C15H22O3\/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16\/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3
InChIKey : FMRHJJZUHUTGKE-UHFFFAOYSA-N
Other name(s) : 2-ethylhexyl salicylate || Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester || CHEMBL1329203 || SCHEMBL29362543 || CHEBI:88639 || DB11062
MW : 250.33
Formula : C15H22O3
CAS_number : 118-60-5
PubChem : 8364
UniChem : FMRHJJZUHUTGKE-UHFFFAOYSA-N
Target
Structures : No structure
Families : Carb_B_Chordata
References (12)
| Title : Assessing the hepatic metabolism of six sunscreen ultraviolet filters: In vitro-in vivo extrapolation approach using human liver microsomes and hepatic parameter predictions for exposure risk assessment - Baviera_2025_Biochem.Pharmacol__117564 |
| Author(s) : Baviera GS , Poli VR , Oka-Duarte L , Santos Barbetta MF , Moraes de Oliveira AR |
| Ref : Biochemical Pharmacology , :117564 , 2025 |
| Abstract : |
| PubMedSearch : Baviera_2025_Biochem.Pharmacol__117564 |
| PubMedID: 41319926 |
| Title : Assessing the hepatic metabolism of six sunscreen ultraviolet filters: In vitro-in vivo extrapolation approach using human liver microsomes and hepatic parameter predictions for exposure risk assessment - Baviera_2025_Biochem.Pharmacol__117564 |
| Author(s) : Baviera GS , Poli VR , Oka-Duarte L , Santos Barbetta MF , Moraes de Oliveira AR |
| Ref : Biochemical Pharmacology , :117564 , 2025 |
| Abstract : |
| PubMedSearch : Baviera_2025_Biochem.Pharmacol__117564 |
| PubMedID: 41319926 |
| Title : Assessing the hepatic metabolism of six sunscreen ultraviolet filters: In vitro-in vivo extrapolation approach using human liver microsomes and hepatic parameter predictions for exposure risk assessment - Baviera_2025_Biochem.Pharmacol__117564 |
| Author(s) : Baviera GS , Poli VR , Oka-Duarte L , Santos Barbetta MF , Moraes de Oliveira AR |
| Ref : Biochemical Pharmacology , :117564 , 2025 |
| Abstract : |
| PubMedSearch : Baviera_2025_Biochem.Pharmacol__117564 |
| PubMedID: 41319926 |
| Title : In vitro metabolism of sunscreen compounds by liquid chromatography\/high-resolution tandem mass spectrometry - Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| Author(s) : Guesmi A , Ohlund L , Sleno L |
| Ref : Rapid Commun Mass Spectrom , 34 :e8679 , 2020 |
| Abstract : |
| PubMedSearch : Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| PubMedID: 31782973 |
| Title : In vitro metabolism of sunscreen compounds by liquid chromatography\/high-resolution tandem mass spectrometry - Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| Author(s) : Guesmi A , Ohlund L , Sleno L |
| Ref : Rapid Commun Mass Spectrom , 34 :e8679 , 2020 |
| Abstract : |
| PubMedSearch : Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| PubMedID: 31782973 |
| Title : In vitro metabolism of sunscreen compounds by liquid chromatography\/high-resolution tandem mass spectrometry - Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| Author(s) : Guesmi A , Ohlund L , Sleno L |
| Ref : Rapid Commun Mass Spectrom , 34 :e8679 , 2020 |
| Abstract : |
| PubMedSearch : Guesmi_2020_Rapid.Commun.Mass.Spectrom_34_e8679 |
| PubMedID: 31782973 |
| Title : Determination of metabolites of the UV filter 2-ethylhexyl salicylate in human urine by online-SPE-LC-MS\/MS - Bury_2019_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1110-1111_59 |
| Author(s) : Bury D , Bruning T , Koch HM |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 1110-1111 :59 , 2019 |
| Abstract : |
| PubMedSearch : Bury_2019_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1110-1111_59 |
| PubMedID: 30780012 |
| Title : Determination of metabolites of the UV filter 2-ethylhexyl salicylate in human urine by online-SPE-LC-MS\/MS - Bury_2019_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1110-1111_59 |
| Author(s) : Bury D , Bruning T , Koch HM |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 1110-1111 :59 , 2019 |
| Abstract : |
| PubMedSearch : Bury_2019_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1110-1111_59 |
| PubMedID: 30780012 |
| Title : Determination of metabolites of the UV filter 2-ethylhexyl salicylate in human urine by online-SPE-LC-MS\/MS - Bury_2019_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1110-1111_59 |
| Author(s) : Bury D , Bruning T , Koch HM |
| Ref : Journal of Chromatography B Analyt Technol Biomed Life Sciences , 1110-1111 :59 , 2019 |
| Abstract : |
| PubMedSearch : Bury_2019_J.Chromatogr.B.Analyt.Technol.Biomed.Life.Sci_1110-1111_59 |
| PubMedID: 30780012 |
| Title : Eco-friendly methodology for efficient synthesis and scale-up of 2-ethylhexyl-p-methoxycinnamate using Rhizopus oryzae lipase and its biological evaluation - Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| Author(s) : Kumar V , Jahan F , Kameswaran K , Mahajan RV , Saxena RK |
| Ref : J Ind Microbiol Biotechnol , 41 :907 , 2014 |
| Abstract : |
| PubMedSearch : Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| PubMedID: 24668019 |
| Title : Eco-friendly methodology for efficient synthesis and scale-up of 2-ethylhexyl-p-methoxycinnamate using Rhizopus oryzae lipase and its biological evaluation - Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| Author(s) : Kumar V , Jahan F , Kameswaran K , Mahajan RV , Saxena RK |
| Ref : J Ind Microbiol Biotechnol , 41 :907 , 2014 |
| Abstract : |
| PubMedSearch : Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| PubMedID: 24668019 |
| Title : Eco-friendly methodology for efficient synthesis and scale-up of 2-ethylhexyl-p-methoxycinnamate using Rhizopus oryzae lipase and its biological evaluation - Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| Author(s) : Kumar V , Jahan F , Kameswaran K , Mahajan RV , Saxena RK |
| Ref : J Ind Microbiol Biotechnol , 41 :907 , 2014 |
| Abstract : |
| PubMedSearch : Kumar_2014_J.Ind.Microbiol.Biotechnol_41_907 |
| PubMedID: 24668019 |