Pyraclostrobin
A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres. It has a role as a xenobiotic, a mitochondrial cytochrome-bc1 complex inhibitor. It is used for control or suppression of fungal diseases on many common crops including: Berries, Bulb, Cucurbit, Fruiting, and Root vegetables, and Cherries. Carboxylesterase, PymH (bacmd-d5dna5), which represents the first enzyme reported to catalyze the hydrolytic cleavage of the C-N bond in pyraclostrobin (Zou 2026)
General
Type : Pyrazole, Carbamate, Fungicide
Chemical_Nomenclature : methyl N-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-N-methoxycarbamate
Canonical SMILES : COC(=O)N(C1=CC=CC=C1COC2=NN(C=C2)C3=CC=C(C=C3)Cl)OC
InChI : InChI=1S\/C19H18ClN3O4\/c1-25-19(24)23(26-2)17-6-4-3-5-14(17)13-27-18-11-12-22(21-18)16-9-7-15(20)8-10-16\/h3-12H,13H2,1-2H3
InChIKey : HZRSNVGNWUDEFX-UHFFFAOYSA-N
Other name(s) : Pyraclostrobine || Headline || Cabrio || CHEBI:78780 || RefChem:6181 || SCHEMBL18441 || CHEMBL519873 || SCHEMBL29488455
MW : 387.8
Formula : C19H18ClN3O4
CAS_number : 175013-18-0
PubChem : 6422843
UniChem : HZRSNVGNWUDEFX-UHFFFAOYSA-N
Target
Structures : No structure
Families : CarbLipBact_1
References (2)
| Title : Enzymatic properties and catalytic mechanism of a novel pyraclostrobin C-N bond-hydrolyzing carboxylesterase from Priestia megaterium GXU087 - Cao_2026_J.Hazard.Mater_510_142095 |
| Author(s) : Cao X , Qiu J , Yang J , Liu X , Mo H , Huang T , Liu Y , Tan H |
| Ref : J Hazard Mater , 510 :142095 , 2026 |
| Abstract : |
| PubMedSearch : Cao_2026_J.Hazard.Mater_510_142095 |
| PubMedID: 42001756 |
| Gene_locus related to this paper: bacmd-d5dna5 |
| Title : The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARgamma activation, in 3T3-L1 cells - Luz_2018_Toxicology_393_150 |
| Author(s) : Luz AL , Kassotis CD , Stapleton HM , Meyer JN |
| Ref : Toxicology , 393 :150 , 2018 |
| Abstract : |
| PubMedSearch : Luz_2018_Toxicology_393_150 |
| PubMedID: 29127035 |