SCHEMBL29599555
This chemiluminescent probe is not substrate but react with a product of reaction of a substrate hydrolyzed by an enzyme: this compound reacts with thiocholine after hydrolysis of acetylthiocholine by cholinesterases. Fluorometric assay of BChE activity based on fluorescence enhancement triggered by thiolene click chemistry using butyrylthiocholine as the substrate
General
Type : Thiocholine reactant, Fluorescent Probe
Chemical_Nomenclature : (2,3-dicyano-4-prop-2-enoyloxyphenyl) prop-2-enoate
Canonical SMILES : C=CC(=O)OC1=C(C(=C(C=C1)OC(=O)C=C)C#N)C#N
InChI : InChI=1S\/C14H8N2O4\/c1-3-13(17)19-11-5-6-12(20-14(18)4-2)10(8-16)9(11)7-15\/h3-6H,1-2H2
InChIKey : XEJNREMFDURMLQ-UHFFFAOYSA-N
Other name(s) :
MW : 268.22
Formula : C14H8N2O4
CAS_number :
PubChem : 90992183
UniChem : XEJNREMFDURMLQ-UHFFFAOYSA-N
Target
Structures : No structure
Families : No family
References (1)
| Title : Thiol-ene click reaction-induced fluorescence enhancement by altering the radiative rate for assaying butyrylcholinesterase activity - Chen_2019_Analyst_144_559 |
| Author(s) : Chen G , Feng H , Xi W , Xu J , Pan S , Qian Z |
| Ref : Analyst , 144 :559 , 2019 |
| Abstract : |
| PubMedSearch : Chen_2019_Analyst_144_559 |
| PubMedID: 30417195 |