M-18C

General

Type : Carboxamide,Piperidine,Indole

Chemical_Nomenclature : N-(3-chlorophenyl)-1-(1-methylindole-2-carbonyl)piperidine-4-carboxamide

Canonical SMILES : CN1C2=CC=CC=C2C=C1C(=O)N3CCC(CC3)C(=O)NC4=CC(=CC=C4)Cl

InChI : InChI=1S\/C22H22ClN3O2\/c1-25-19-8-3-2-5-16(19)13-20(25)22(28)26-11-9-15(10-12-26)21(27)24-18-7-4-6-17(23)14-18\/h2-8,13-15H,9-12H2,1H3,(H,24,27)

InChIKey : MXGCUBKWNANRFD-UHFFFAOYSA-N

Other name(s) : SCHEMBL23086088,MAGLZ-18(c)


MW : 395.9

Formula : C22H22ClN3O2

CAS_number :

PubChem : 156150511

UniChem : MXGCUBKWNANRFD-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : M-18C ligand of proteins in family: Monoglyceridelipase_lysophospholip

Stucture :

Protein : human-MGLL

References (1)

Title : Novel MAGL Inhibitors Alleviate LPS-Induced Acute Kidney Injury by Inhibiting NLRP3 Inflammatory Vesicles, Modulating Intestinal Flora, Repairing the Intestinal Barrier, and Interfering with Serum Metabolism - Xiang_2023_Molecules_28_7245
Author(s) : Xiang H , Wang Y , Yang L , Liu M , Sun C , Gu Y , Yao J
Ref : Molecules , 28 : , 2023
Abstract : Xiang_2023_Molecules_28_7245
ESTHER : Xiang_2023_Molecules_28_7245
PubMedSearch : Xiang_2023_Molecules_28_7245
PubMedID: 37959665
Gene_locus related to this paper: human-MGLL