human-MGLL
Homo sapiens (Human) Monoglyceride lipase (MAGL) lysophospholipase homolog
Comment
Human monoacylglycerol lipase (hMAGL Monoglyceride lipase MGLL) converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth
Relationship
Family : Monoglyceridelipase_lysophospholip
Block : X
Position in NCBI Life Tree : Homo sapiens
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N EMolecular evidence
No mutation
3HJU - Crystal structure of human monoglyceride lipase
3JW8 - Crystal structure of human Mono glyceride lipase
3JWE - Crystal structure of human Mono glyceride lipase in complex with SAR629
3PE6 - Crystal Structure of a soluble form of human MGLL in complex with an inhibitor
4UUQ - Crystal structure of human mono-glyceride lipase in complex with SAR127303
5ZUN - Crystal structure of human monoacylglycerol lipase in complex with compound 3l
6AX1 - Structure of human monoacylglycerol lipase bound to a covalent inhibitor
6BQ0 - Structure of human monoacylglycerol lipase bound to PF-06795071 a covalent inhibitor
7L4T - Crystal structure of human monoacylglycerol lipase in complex with compound 1 SCHEMBL19834081
7L4U - Crystal structure of human monoacylglycerol lipase in complex with compound 1h XP7-7L4U
7L4W - Crystal structure of human monoacylglycerol lipase in complex with compound 2d SCHEMBL19421059
7L50 - Crystal structure of human monoacylglycerol lipase in complex with compound 4f SCHEMBL19421119
7PRM - Crystal structure of human monoglyceride lipase with compound 13, YH149
7ZPG - Crystal structure of human monoglyceride lipase with ligand MAGLi-432
8AQF - Crystal structure of human monoacylglycerol lipase in complex with compound LEI-515
8PTC - Crystal structure of human monoacylglycerol lipase in complex with compound 5d
8PTQ - Crystal structure of human monoacylglycerol lipase in complex with compound 5l
8PTR - Crystal structure of human monoacylglycerol lipase in complex with compound 5r
8RVF - Crystal structure of human monoacylglycerol lipase in complex with compound 5
9F8A - Crystal structure of human monoacylglycerol lipase in complex with compound 7a SCHEMBL21061872
9F8B - Crystal structure of human monoacylglycerol lipase in complex with compound 7n SCHEMBL22462763
9F8C - Crystal structure of human monoacylglycerol lipase in complex with compound 7m SCHEMBL22488617
9F8D - Crystal structure of human monoacylglycerol lipase in complex with compound 7i SCHEMBL22491361
9FY5 - Crystal structure of human monoacylglycerol lipase in complex with compound SCHEMBL23211786
9G4M - Crystal structure of monoacylglycerol lipase with BODIPY labeled probe
No kinetic
No disease
(R)-3t
1-(2-Morpholine-acetamido)-tanshinone-IIA
2-methyl-pentane-2,4-diol
5ZUN-3l
64D
6AX1-cp3
ABD-1970
ABX-1431
AKU-005
AM6580
AM6701
AM9928
Benzisothiazolinone-13
Benzo-triazole-carbonylpiperidin-benzodioxol-fluorophenylazetidin-2-one-5v
Beta-Amyrin
CAY10499
CHEMBL4437989
CHEMBL4559005
CHEMBL5176915
Cpd37-Fluoroindol-carbamate
Disulfiram
F4P
FEPAD
JJKK-048
JNJ-42226314
JW651
JZL184
JZL195
KML29
LEI-515
LY2183240
M-18C
MAGL-2305
MAGL-IN-10-Cpd28
MAGL11
MAGL17b
MAGL23
MAGLi-432
MGL-Inhibitor-21
MGL-Inhibitor-26
MGLL-IN-Cpd118
MGLL-IN-Cpd239
MGLL-IN-Cpd34
MJN110
N-Arachidonylmaleimide
NSD1819
Octhilinone
Octyl-Benzisothiazolinone
PF-06795071
Pristimerin
Pyrazolopyridine-Cpd37
QST-0837
SA-57
SCHEMBL19421059
SCHEMBL19421119
SCHEMBL19834081
SCHEMBL21061872
SCHEMBL22462761
SCHEMBL22462763
SCHEMBL22488617
SCHEMBL22491361
SCHEMBL23211786
T-401
Triazole-carbonylpiperidin-diphenylazetidin-2-one-5d
URB597
URB602
XP7-7L4U
YH149
YH168
ZINC12863377
ZINC24092691
ZYH
ZYH-deriv-F
Database
Sequence
Peptide
MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT PKALIFVSHG AGEHSGRYEE LARMLMGLDL LVFAHDHVGH GQSEGERMVV SDFHVFVRDV LQHVDSMQKD YPGLPVFLLG HSMGGAIAIL TAAERPGHFA GMVLISPLVL ANPESATTFK VLAAKVLNLV LPNLSLGPID SSVLSRNKTE VDIYNSDPLI CRAGLKVCFG IQLLNAVSRV ERALPKLTVP FLLLQGSADR LCDSKGAYLL MELAKSQDKT LKIYEGAYHV LHKELPEVTN SVFHEINMWV SQRTATAGTA SPP
References (109)
| Title : Radiosynthesis and evaluation of novel (18)F labeled PET ligands for imaging monoacylglycerol lipase - Li_2025_Eur.J.Med.Chem_285_117246 |
| Author(s) : Li Y , Mori W , Chaudhary A , Zhao C , Yamasaki T , Zhang Z , Feng S , Ware T , Rong J , Fujinaga M , Chen J , Kumata K , Zhang Y , Hu K , Xie L , Zhou X , Song Z , Gao Y , Sun Z , Patel JS , Zhai C , Yuan KY , Collier TL , Ran C , Collin L , Haider A , Grether U , Wittwer MB , Cravatt BF , Zhang MR , Liang SH |
| Ref : Eur Journal of Medicinal Chemistry , 285 :117246 , 2025 |
| Abstract : |
| PubMedSearch : Li_2025_Eur.J.Med.Chem_285_117246 |
| PubMedID: 39793441 |
| Gene_locus related to this paper: human-MGLL |
| Title : Binding of the monoacylglycerol lipase (MAGL) radiotracer [(3)H]T-401 in the rat brain after status epilepticus - Mikkelsen_2024_Neurochem.Int__105717 |
| Author(s) : Mikkelsen JD , Aripaka SS , Egilmez CB , Pazarlar BA |
| Ref : Neurochem Int , :105717 , 2024 |
| Abstract : |
| PubMedSearch : Mikkelsen_2024_Neurochem.Int__105717 |
| PubMedID: 38447759 |
| Gene_locus related to this paper: human-MGLL |
| Title : Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia - Martinez-Rivera_2024_bioRxiv__ |
| Author(s) : Martinez-Rivera A , Fetcho RN , Birmingham L , Jiu JX , Yang R , Foord C , Scala-Chavez D , Mekawy N , Pleil K , Pickel VM , Liston C , Castorena CM , Levitz J , Pan YX , Briand LA , Rajadhyaksha AM , Lee FS |
| Ref : Biorxiv , : , 2024 |
| Abstract : |
| PubMedSearch : Martinez-Rivera_2024_bioRxiv__ |
| PubMedID: 38766079 |
| Gene_locus related to this paper: human-MGLL |
| Title : Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia - Martinez-Rivera_2024_Sci.Adv_10_eadq4779 |
| Author(s) : Martinez-Rivera A , Fetcho RN , Birmingham L , Xu J , Yang R , Foord C , Scala-Chavez D , Mekawy N , Pleil K , Pickel VM , Liston C , Castorena CM , Levitz J , Pan YX , Briand LA , Rajadhyaksha AM , Lee FS |
| Ref : Sci Adv , 10 :eadq4779 , 2024 |
| Abstract : |
| PubMedSearch : Martinez-Rivera_2024_Sci.Adv_10_eadq4779 |
| PubMedID: 39612328 |
| Gene_locus related to this paper: human-MGLL |
| Title : Acute Effects of Monoacylglycerol Lipase Inhibitor ABX1431 on Neuronal Hyperexcitability, Nociception, Locomotion, and the Endocannabinoid System in HIV-1 Tat Male Mice - Yadav-Samudrala_2024_Cannabis.Cannabinoid.Res__ |
| Author(s) : Yadav-Samudrala BJ , Ravula HP , Barmada KM , Dodson H , Poklis JL , Ignatowska-Jankowska BM , Lichtman AH , Reissner KJ , Fitting S |
| Ref : Cannabis Cannabinoid Res , : , 2024 |
| Abstract : |
| PubMedSearch : Yadav-Samudrala_2024_Cannabis.Cannabinoid.Res__ |
| PubMedID: 38394322 |
| Gene_locus related to this paper: human-MGLL |
| Title : Potential for in vivo visualization of intracellular pH gradient in the brain using PET imaging - Yamasaki_2024_Brain.Commun_6_fcae172 |
| Author(s) : Yamasaki T , Mori W , Ohkubo T , Hiraishi A , Zhang Y , Kurihara Y , Nengaki N , Tashima H , Fujinaga M , Zhang MR |
| Ref : Brain Commun , 6 :fcae172 , 2024 |
| Abstract : |
| PubMedSearch : Yamasaki_2024_Brain.Commun_6_fcae172 |
| PubMedID: 38863573 |
| Gene_locus related to this paper: human-MGLL |
| Title : A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation - League_2024_Front.Immunol_15_1374301 |
| Author(s) : League AF , Yadav-Samudrala BJ , Kolagani R , Cline CA , Jacobs IR , Manke J , Niphakis MJ , Cravatt BF , Lichtman AH , Ignatowska-Jankowska BM , Fitting S |
| Ref : Front Immunol , 15 :1374301 , 2024 |
| Abstract : |
| PubMedSearch : League_2024_Front.Immunol_15_1374301 |
| PubMedID: 38835765 |
| Gene_locus related to this paper: human-MGLL |
| Title : Monoacylglycerol Lipase Inhibition Using ABX-1431 Attenuates Cerebral Ischaemia Early After Traumatic Brain Injury - Bragin_2024_Adv.Exp.Med.Biol_1463_109 |
| Author(s) : Bragin DE , Bragina OA , Covey DP , Trofimov AO , Nemoto EM , Mayer AR |
| Ref : Advances in Experimental Medicine & Biology , 1463 :109 , 2024 |
| Abstract : |
| PubMedSearch : Bragin_2024_Adv.Exp.Med.Biol_1463_109 |
| PubMedID: 39400809 |
| Gene_locus related to this paper: human-MGLL |
| Title : MAGL protects against renal fibrosis through inhibiting tubular cell lipotoxicity - Zhou_2024_Theranostics_14_1583 |
| Author(s) : Zhou S , Ling X , Zhu J , Liang Y , Feng Q , Xie C , Li J , Chen Q , Chen S , Miao J , Zhang M , Li Z , Shen W , Li X , Wu Q , Wang X , Liu R , Wang C , Hou FF , Kong Y , Liu Y , Zhou L |
| Ref : Theranostics , 14 :1583 , 2024 |
| Abstract : |
| PubMedSearch : Zhou_2024_Theranostics_14_1583 |
| PubMedID: 38389852 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization - Butini_2024_J.Med.Chem__ |
| Author(s) : Butini S , Grether U , Jung KM , Ligresti A , Allara M , Postmus AGJ , Maramai S , Brogi S , Papa A , Carullo G , Sykes D , Veprintsev D , Federico S , Grillo A , Di Guglielmo B , Ramunno A , Stevens AF , Heer D , Lamponi S , Gemma S , Benz J , Di Marzo V , van der Stelt M , Piomelli D , Campiani G |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Butini_2024_J.Med.Chem__ |
| PubMedID: 38241614 |
| Gene_locus related to this paper: human-MGLL |
| Title : Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors - Kuhn_2024_J.Med.Chem__ |
| Author(s) : Kuhn B , Ritter M , Hornsperger B , Bell C , Kocer B , Rombach D , Lutz MDR , Gobbi L , Kuratli M , Bartelmus C , Burkler M , Koller R , Tosatti P , Ruf I , Guerard M , Pavlovic A , Stephanus J , O'Hara F , Wetzl D , Saal W , Stihle M , Roth D , Hug M , Huber S , Heer D , Kroll C , Topp A , Schneider M , Gertsch J , Glasmacher S , van der Stelt M , Martella A , Wittwer MB , Collin L , Benz J , Richter H , Grether U |
| Ref : Journal of Medicinal Chemistry , : , 2024 |
| Abstract : |
| PubMedSearch : Kuhn_2024_J.Med.Chem__ |
| PubMedID: 39360636 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of a Highly Selective NanoBRET Probe to Assess MAGL Inhibition in Live Cells - Gazzi_2024_Chembiochem__e202400704 |
| Author(s) : Gazzi T , Brennecke B , Olikauskas V , Hochstrasser R , Wang H , Keen Chao S , Atz K , Mostinski Y , Topp A , Heer D , Kaufmann I , Ritter M , Gobbi L , Hornsperger B , Wagner B , Richter H , O'Hara F , Wittwer MB , Jul Hansen D , Collin L , Kuhn B , Benz J , Grether U , Nazare M |
| Ref : Chembiochem , :e202400704 , 2024 |
| Abstract : |
| PubMedSearch : Gazzi_2024_Chembiochem__e202400704 |
| PubMedID: 39607084 |
| Gene_locus related to this paper: human-MGLL |
| Title : Compound 4f, a novel brain-penetrant reversible monoacylglycerol inhibitor, ameliorates neuroinflammation, neuronal cell loss, and cognitive impairment in mice with kainic acid-induced neurodegeneration - Arimura_2024_PLoS.One_19_e0312090 |
| Author(s) : Arimura N , Maeda C , Aoyama K , Yamaguchi N , Sugiura A , Takahashi Y , Maeda R , Ando T , Kamata M , Matsui H , Tanaka M |
| Ref : PLoS ONE , 19 :e0312090 , 2024 |
| Abstract : |
| PubMedSearch : Arimura_2024_PLoS.One_19_e0312090 |
| PubMedID: 39570850 |
| Gene_locus related to this paper: human-MGLL |
| Title : Fluorescence-Based Enzyme Activity Assay: Ascertaining the Activity and Inhibition of Endocannabinoid Hydrolytic Enzymes - Ciuffreda_2024_Int.J.Mol.Sci_25_7693 |
| Author(s) : Ciuffreda P , Xynomilakis O , Casati S , Ottria R |
| Ref : Int J Mol Sci , 25 :7693 , 2024 |
| Abstract : |
| PubMedSearch : Ciuffreda_2024_Int.J.Mol.Sci_25_7693 |
| PubMedID: 39062935 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
| Title : Inhibition of Monoacylglycerol Lipase Decreases Angiogenic Features of Endothelial Cells via Release of Tissue Inhibitor of Metalloproteinase-1 from Lung Cancer Cells - Wittig_2023_Cells_12_1757 |
| Author(s) : Wittig F , Henkel L , Pruser JL , Merkord J , Ramer R , Hinz B |
| Ref : Cells , 12 :1757 , 2023 |
| Abstract : |
| PubMedSearch : Wittig_2023_Cells_12_1757 |
| PubMedID: 37443791 |
| Gene_locus related to this paper: human-MGLL |
| Title : Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice - Goeritzer_2023_Int.J.Mol.Sci_24_ |
| Author(s) : Goeritzer M , Kuentzel KB , Beck S , Korbelius M , Rainer S , Bradic I , Kolb D , Mussbacher M , Schrottmaier WC , Assinger A , Schlagenhauf A , Rost R , Gottschalk B , Eichmann TO , Zullig T , Graier WF , Vujic N , Kratky D |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : |
| PubMedSearch : Goeritzer_2023_Int.J.Mol.Sci_24_ |
| PubMedID: 36834530 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache - Liktor-Busa_2023_Front.Pain.Res.(Lausanne)_4_1171188 |
| Author(s) : Liktor-Busa E , Levine AA , Palomino SM , Singh S , Wahl J , Vanderah TW , Stella N , Largent-Milnes TM |
| Ref : Front Pain Res (Lausanne) , 4 :1171188 , 2023 |
| Abstract : |
| PubMedSearch : Liktor-Busa_2023_Front.Pain.Res.(Lausanne)_4_1171188 |
| PubMedID: 37287623 |
| Gene_locus related to this paper: human-ABHD6 , human-MGLL |
| Title : Supervised screening of Tecovirimat-like compounds as potential inhibitors for the monkeypox virus E8L protein - Mehmood_2023_J.Biomol.Struct.Dyn__1 |
| Author(s) : Mehmood A , Nawab S , Jia G , Kaushik AC , Wei DQ |
| Ref : J Biomol Struct Dyn , :1 , 2023 |
| Abstract : |
| PubMedSearch : Mehmood_2023_J.Biomol.Struct.Dyn__1 |
| PubMedID: 37561169 |
| Gene_locus related to this paper: human-MGLL |
| Title : Novel MAGL Inhibitors Alleviate LPS-Induced Acute Kidney Injury by Inhibiting NLRP3 Inflammatory Vesicles, Modulating Intestinal Flora, Repairing the Intestinal Barrier, and Interfering with Serum Metabolism - Xiang_2023_Molecules_28_7245 |
| Author(s) : Xiang H , Wang Y , Yang L , Liu M , Sun C , Gu Y , Yao J |
| Ref : Molecules , 28 : , 2023 |
| Abstract : |
| PubMedSearch : Xiang_2023_Molecules_28_7245 |
| PubMedID: 37959665 |
| Gene_locus related to this paper: human-MGLL |
| Title : MAGL inhibition relieves synovial inflammation and pain via regulating NOX4-Nrf2 redox balance in osteoarthritis - Li_2023_Free.Radic.Biol.Med_208_13 |
| Author(s) : Li X , Tao H , Zhou J , Zhang L , Shi Y , Zhang C , Sun W , Chu M , Chen K , Gu C , Yang X , Geng D , Hao Y |
| Ref : Free Radic Biol Med , 208 :13 , 2023 |
| Abstract : |
| PubMedSearch : Li_2023_Free.Radic.Biol.Med_208_13 |
| PubMedID: 37516370 |
| Gene_locus related to this paper: human-MGLL |
| Title : IL-8-induced CXCR2 down-regulation in circulating monocytes in hepatocellular carcinoma is partially dependent on MAGL - Liu_2023_BMC.Cancer_23_626 |
| Author(s) : Liu CZ , Liu XB , Sun J , Yu CQ , Yao JC , Liu Z , Hao JC |
| Ref : BMC Cancer , 23 :626 , 2023 |
| Abstract : |
| PubMedSearch : Liu_2023_BMC.Cancer_23_626 |
| PubMedID: 37403022 |
| Gene_locus related to this paper: human-MGLL |
| Title : Potent dual MAGL\/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain - Della Pietra_2023_J.Headache.Pain_24_38 |
| Author(s) : Della Pietra A , Krivoshein G , Ivanov K , Giniatullina R , Jyrkkanen HK , Leinonen V , Lehtonen M , van den Maagdenberg A , Savinainen J , Giniatullin R |
| Ref : J Headache Pain , 24 :38 , 2023 |
| Abstract : |
| PubMedSearch : Della Pietra_2023_J.Headache.Pain_24_38 |
| PubMedID: 37038131 |
| Gene_locus related to this paper: human-MGLL |
| Title : Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain - He_2022_Eur.J.Med.Chem_243_114750 |
| Author(s) : He Y , Grether U , Taddio MF , Meier C , Keller C , Edelmann MR , Honer M , Huber S , Wittwer MB , Heer D , Richter H , Collin L , Hug MN , Hilbert M , Postmus AGJ , Stevens AF , van der Stelt M , Kramer SD , Schibli R , Mu L , Gobbi LC |
| Ref : Eur Journal of Medicinal Chemistry , 243 :114750 , 2022 |
| Abstract : |
| PubMedSearch : He_2022_Eur.J.Med.Chem_243_114750 |
| PubMedID: 36137365 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : ABX-1431 inhibits the development of endometrial adenocarcinoma and reverses progesterone resistance by targeting MGLL - Ma_2022_Cell.Death.Dis_13_1067 |
| Author(s) : Ma X , Xia M , Wei L , Guo K , Sun R , Liu Y , Qiu C , Jiang J |
| Ref : Cell Death Dis , 13 :1067 , 2022 |
| Abstract : |
| PubMedSearch : Ma_2022_Cell.Death.Dis_13_1067 |
| PubMedID: 36550099 |
| Gene_locus related to this paper: human-MGLL |
| Title : Hexafluoroisopropyl carbamates as selective MAGL and dual MAGL\/FAAH inhibitors: biochemical and physicochemical properties - Barth_2022_ChemMedChem__ |
| Author(s) : Barth M , Rudolph S , Kampschulze J , Meyer Zu Vilsendorf I , Hanekamp W , Mulac D , Langer K , Lehr M |
| Ref : ChemMedChem , : , 2022 |
| Abstract : |
| PubMedSearch : Barth_2022_ChemMedChem__ |
| PubMedID: 35072346 |
| Gene_locus related to this paper: human-MGLL |
| Title : Cannabis-based medicine in treatment of patients with Gilles de la Tourette syndrome - Szejko_2022_Neurol.Neurochir.Pol_56_28 |
| Author(s) : Szejko N , Saramak K , Lombroso A , Muller-Vahl K |
| Ref : Neurol Neurochir Pol , 56 :28 , 2022 |
| Abstract : |
| PubMedSearch : Szejko_2022_Neurol.Neurochir.Pol_56_28 |
| PubMedID: 34708399 |
| Gene_locus related to this paper: human-MGLL |
| Title : The endocannabinoid system impacts seizures in a mouse model of Dravet syndrome - Anderson_2022_Neuropharmacol_205_108897 |
| Author(s) : Anderson LL , Doohan PT , Hawkins NA , Bahceci D , Garai S , Thakur GA , Kearney JA , Arnold JC |
| Ref : Neuropharmacology , 205 :108897 , 2022 |
| Abstract : |
| PubMedSearch : Anderson_2022_Neuropharmacol_205_108897 |
| PubMedID: 34822817 |
| Gene_locus related to this paper: human-MGLL |
| Title : Chemical Probes to Control and Visualize Lipid Metabolism in the Brain - Punt_2022_Acc.Chem.Res_55_3205 |
| Author(s) : Punt JM , van der Vliet D , van der Stelt M |
| Ref : Acc Chem Res , 55 :3205 , 2022 |
| Abstract : |
| PubMedSearch : Punt_2022_Acc.Chem.Res_55_3205 |
| PubMedID: 36283077 |
| Gene_locus related to this paper: human-MGLL |
| Title : Discovery, synthesis and evaluation of novel reversible monoacylglycerol lipase radioligands bearing a morpholine-3-one scaffold - He_2022_Nucl.Med.Biol_108-109_24 |
| Author(s) : He Y , Gobbi LC , Herde AM , Rombach D , Ritter M , Kuhn B , Wittwer MB , Heer D , Hornsperger B , Bell C , O'Hara F , Benz J , Honer M , Keller C , Collin L , Richter H , Schibli R , Grether U , Mu L |
| Ref : Nucl Med Biol , 108-109 :24 , 2022 |
| Abstract : |
| PubMedSearch : He_2022_Nucl.Med.Biol_108-109_24 |
| PubMedID: 35248850 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging - He_2022_J.Med.Chem_65_2191 |
| Author(s) : He Y , Schild M , Grether U , Benz J , Leibrock L , Heer D , Topp A , Collin L , Kuhn B , Wittwer M , Keller C , Gobbi LC , Schibli R , Mu L |
| Ref : Journal of Medicinal Chemistry , 65 :2191 , 2022 |
| Abstract : |
| PubMedSearch : He_2022_J.Med.Chem_65_2191 |
| PubMedID: 35089028 |
| Gene_locus related to this paper: human-MGLL |
| Title : A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature - Kemble_2022_PLoS.One_17_e0268590 |
| Author(s) : Kemble AM , Hornsperger B , Ruf I , Richter H , Benz J , Kuhn B , Heer D , Wittwer M , Engelhardt B , Grether U , Collin L |
| Ref : PLoS ONE , 17 :e0268590 , 2022 |
| Abstract : |
| PubMedSearch : Kemble_2022_PLoS.One_17_e0268590 |
| PubMedID: 36084029 |
| Gene_locus related to this paper: human-MGLL |
| Title : A novel monoacylglycerol lipase-targeted (18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network - Cheng_2022_Acta.Pharmacol.Sin__ |
| Author(s) : Cheng R , Fujinaga M , Yang J , Rong J , Haider A , Ogasawara D , Van RS , Shao T , Chen Z , Zhang X , Calderon Leon ER , Zhang Y , Mori W , Kumata K , Yamasaki T , Xie L , Sun S , Wang L , Ran C , Shao Y , Cravatt B , Josephson L , Zhang MR , Liang SH |
| Ref : Acta Pharmacol Sin , : , 2022 |
| Abstract : |
| PubMedSearch : Cheng_2022_Acta.Pharmacol.Sin__ |
| PubMedID: 35513432 |
| Gene_locus related to this paper: human-MGLL |
| Title : Inhibiting Endocannabinoid Hydrolysis as Emerging Analgesic Strategy Targeting a Spectrum of Ion Channels Implicated in Migraine Pain - Della Pietra_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Della Pietra A , Savinainen J , Giniatullin R |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : |
| PubMedSearch : Della Pietra_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 35457225 |
| Gene_locus related to this paper: human-MGLL |
| Title : MAGL inhibitor NanoMicellar formulation (MAGL-NanoMicellar) for the development of an antiglaucoma eye drop - Chetoni_2022_Int.J.Pharm__122078 |
| Author(s) : Chetoni P , Burgalassi S , Zucchetti E , Granchi C , Minutolo F , Tampucci S , Monti D |
| Ref : Int J Pharm , :122078 , 2022 |
| Abstract : |
| PubMedSearch : Chetoni_2022_Int.J.Pharm__122078 |
| PubMedID: 35932931 |
| Gene_locus related to this paper: human-MGLL |
| Title : Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency - Galvani_2022_J.Chem.Inf.Model__ |
| Author(s) : Galvani F , Scalvini L , Rivara S , Lodola A , Mor M |
| Ref : J Chem Inf Model , : , 2022 |
| Abstract : |
| PubMedSearch : Galvani_2022_J.Chem.Inf.Model__ |
| PubMedID: 35580195 |
| Gene_locus related to this paper: human-MGLL |
| Title : Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase - Benchama_2022_Sci.Rep_12_5328 |
| Author(s) : Benchama O , Tyukhtenko S , Malamas MS , Williams MK , Makriyannis A , Avraham HK |
| Ref : Sci Rep , 12 :5328 , 2022 |
| Abstract : |
| PubMedSearch : Benchama_2022_Sci.Rep_12_5328 |
| PubMedID: 35351947 |
| Gene_locus related to this paper: human-MGLL |
| Title : First-in-human in vivo undefined imaging and quantification of monoacylglycerol lipase in the brain: a PET study with (18)F-T-401 - Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__ |
| Author(s) : Takahata K , Seki C , Kimura Y , Kubota M , Ichise M , Sano Y , Yamamoto Y , Tagai K , Shimada H , Kitamura S , Matsuoka K , Endo H , Shinotoh H , Kawamura K , Zhang MR , Takado Y , Higuchi M |
| Ref : Eur J Nucl Med Mol Imaging , : , 2022 |
| Abstract : |
| PubMedSearch : Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__ |
| PubMedID: 35022846 |
| Gene_locus related to this paper: human-MGLL |
| Title : Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex - Pavon_2021_Neurobiol.Stress_14_100293 |
| Author(s) : Pavon FJ , Polis IY , Stouffer DG , Cravatt BF , Roberto M , Martin-Fardon R , Rodriguez de Fonseca F , Parsons LH , Serrano A |
| Ref : Neurobiol Stress , 14 :100293 , 2021 |
| Abstract : |
| PubMedSearch : Pavon_2021_Neurobiol.Stress_14_100293 |
| PubMedID: 33490317 |
| Gene_locus related to this paper: human-MGLL |
| Title : Endocannabinoid Modulation Using Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A Phase 1 Randomized, Placebo-Controlled Study - Muller-Vahl_2021_Pharmacopsychiatry__ |
| Author(s) : Muller-Vahl KR , Fremer C , Beals C , Ivkovic J , Loft H , Schindler C |
| Ref : Pharmacopsychiatry , : , 2021 |
| Abstract : |
| PubMedSearch : Muller-Vahl_2021_Pharmacopsychiatry__ |
| PubMedID: 34847610 |
| Gene_locus related to this paper: human-MGLL |
| Title : Heterocyclic Compounds as Monoacylglycerol Lipase (MAGL) Inhibitors - |
| Author(s) : Sabnis RW |
| Ref : ACS Med Chem Lett , 12 :536 , 2021 |
| PubMedID: 33859792 |
| Gene_locus related to this paper: human-MGLL |
| Title : Novel Oxazine Monoacylglycerol Lipase (MAGL) Inhibitors - |
| Author(s) : Sabnis RW |
| Ref : ACS Med Chem Lett , 12 :312 , 2021 |
| PubMedID: 33738048 |
| Gene_locus related to this paper: human-MGLL |
| Title : Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold - Rong_2021_J.Med.Chem__ |
| Author(s) : Rong J , Mori W , Xia X , Schafroth MA , Zhao C , Van RS , Yamasaki T , Chen J , Xiao Z , Haider A , Ogasawara D , Hiraishi A , Shao T , Zhang Y , Chen Z , Pang F , Hu K , Xie L , Fujinaga M , Kumata K , Gou Y , Fang Y , Gu S , Wei H , Bao L , Xu H , Collier TL , Shao Y , Carson RE , Cravatt BF , Wang L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Rong_2021_J.Med.Chem__ |
| PubMedID: 34569803 |
| Gene_locus related to this paper: human-MGLL |
| Title : Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat - League_2021_Front.Neurol_12_651272 |
| Author(s) : League AF , Gorman BL , Hermes DJ , Johnson CT , Jacobs IR , Yadav-Samudrala BJ , Poklis JL , Niphakis MJ , Cravatt BF , Lichtman AH , Ignatowska-Jankowska BM , Fitting S |
| Ref : Front Neurol , 12 :651272 , 2021 |
| Abstract : |
| PubMedSearch : League_2021_Front.Neurol_12_651272 |
| PubMedID: 34484091 |
| Gene_locus related to this paper: human-MGLL |
| Title : The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB(1) Cannabinoid Receptor - Pruser_2021_Mol.Cancer.Ther_20_787 |
| Author(s) : Pruser JL , Ramer R , Wittig F , Ivanov I , Merkord J , Hinz B |
| Ref : Mol Cancer Ther , 20 :787 , 2021 |
| Abstract : |
| PubMedSearch : Pruser_2021_Mol.Cancer.Ther_20_787 |
| PubMedID: 33632876 |
| Gene_locus related to this paper: human-MGLL |
| Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__ |
| Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M |
| Ref : Journal of Medicinal Chemistry , : , 2021 |
| Abstract : |
| PubMedSearch : Ikeda_2021_J.Med.Chem__ |
| PubMedID: 34328319 |
| Gene_locus related to this paper: human-MGLL |
| Title : Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping - Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| Author(s) : Chen Z , Mori W , Rong J , Schafroth MA , Shao T , Van RS , Ogasawara D , Yamasaki T , Hiraishi A , Hatori A , Chen J , Zhang Y , Hu K , Fujinaga M , Sun J , Yu Q , Collier TL , Shao Y , Cravatt BF , Josephson L , Zhang MR , Liang SH |
| Ref : Acta Pharm Sin B , 11 :1686 , 2021 |
| Abstract : |
| PubMedSearch : Chen_2021_Acta.Pharm.Sin.B_11_1686 |
| PubMedID: 34221877 |
| Gene_locus related to this paper: human-MGLL |
| Title : Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening - Xiong_2021_Bioorg.Med.Chem.Lett__127986 |
| Author(s) : Xiong F , Ding X , Zhang H , Luo X , Chen K , Jiang H , Luo C , Xu H |
| Ref : Bioorganic & Medicinal Chemistry Lett , :127986 , 2021 |
| Abstract : |
| PubMedSearch : Xiong_2021_Bioorg.Med.Chem.Lett__127986 |
| PubMedID: 33766770 |
| Gene_locus related to this paper: human-MGLL |
| Title : 1-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1 - Farah_2021_Biochem.Biophys.Res.Commun_591_31 |
| Author(s) : Farah SI , Hilston S , Tran N , Zvonok N , Makriyannis A |
| Ref : Biochemical & Biophysical Research Communications , 591 :31 , 2021 |
| Abstract : |
| PubMedSearch : Farah_2021_Biochem.Biophys.Res.Commun_591_31 |
| PubMedID: 34995983 |
| Gene_locus related to this paper: human-ABHD6 , human-MGLL |
| Title : Research progress on FASN and MGLL in the regulation of abnormal lipid metabolism and the relationship between tumor invasion and metastasis - Zhang_2021_Front.Med__ |
| Author(s) : Zhang J , Song Y , Shi Q , Fu L |
| Ref : Front Med , : , 2021 |
| Abstract : |
| PubMedSearch : Zhang_2021_Front.Med__ |
| PubMedID: 33973101 |
| Gene_locus related to this paper: human-FASN , human-MGLL |
| Title : Conformational gating, dynamics and allostery in human monoacylglycerol lipase - Tyukhtenko_2020_Sci.Rep_10_18531 |
| Author(s) : Tyukhtenko S , Ma X , Rajarshi G , Karageorgos I , Anderson KW , Hudgens JW , Guo JJ , Nasr ML , Zvonok N , Vemuri K , Wagner G , Makriyannis A |
| Ref : Sci Rep , 10 :18531 , 2020 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2020_Sci.Rep_10_18531 |
| PubMedID: 33116203 |
| Gene_locus related to this paper: human-MGLL |
| Title : Termination of acute stress response by the endocannabinoid system is regulated through LSD1-mediated transcriptional repression of 2-AG hydrolases ABHD6 and MAGL - Longaretti_2020_J.Neurochem__e15000 |
| Author(s) : Longaretti A , Forastieri C , Gabaglio M , Rubino T , Battaglioli E , Rusconi F |
| Ref : Journal of Neurochemistry , :e15000 , 2020 |
| Abstract : |
| PubMedSearch : Longaretti_2020_J.Neurochem__e15000 |
| PubMedID: 32141088 |
| Gene_locus related to this paper: human-ABHD6 , human-MGLL , mouse-ABHD6 , mouse-MGLL |
| Title : The novel MAGL inhibitor MJN110 enhances responding to reward-predictive incentive cues by activation of CB1 receptors - Feja_2020_Neuropharmacol_162_107814 |
| Author(s) : Feja M , Leigh MPK , Baindur AN , McGraw JJ , Wakabayashi KT , Cravatt BF , Bass CE |
| Ref : Neuropharmacology , 162 :107814 , 2020 |
| Abstract : |
| PubMedSearch : Feja_2020_Neuropharmacol_162_107814 |
| PubMedID: 31628934 |
| Gene_locus related to this paper: human-MGLL |
| Title : The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain - Thompson_2020_J.Pharmacol.Exp.Ther_373_230 |
| Author(s) : Thompson AL , Grenald SA , Ciccone HA , BassiriRad N , Niphakis MJ , Cravatt BF , Largent-Milnes TM , Vanderah TW |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 373 :230 , 2020 |
| Abstract : |
| PubMedSearch : Thompson_2020_J.Pharmacol.Exp.Ther_373_230 |
| PubMedID: 32054717 |
| Gene_locus related to this paper: human-MGLL |
| Title : Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein - Liu_2020_Cell.Death.Differ__ |
| Author(s) : Liu R , Wang X , Curtiss C , Sheikh MS , Huang Y |
| Ref : Cell Death Differ , : , 2020 |
| Abstract : |
| PubMedSearch : Liu_2020_Cell.Death.Differ__ |
| PubMedID: 32376875 |
| Gene_locus related to this paper: human-MGLL |
| Title : Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice - Muldoon_2020_Neuropharmacol__108170 |
| Author(s) : Muldoon PP , Akinola LS , Schlosburg JE , Lichtman AH , Sim-Selley LJ , Mahadevan A , Cravatt BF , Damaj MI |
| Ref : Neuropharmacology , :108170 , 2020 |
| Abstract : |
| PubMedSearch : Muldoon_2020_Neuropharmacol__108170 |
| PubMedID: 32479813 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors - Granchi_2020_Eur.J.Med.Chem_209_112857 |
| Author(s) : Granchi C , Bononi G , Ferrisi R , Gori E , Mantini G , Glasmacher S , Poli G , Palazzolo S , Caligiuri I , Rizzolio F , Canzonieri V , Perin T , Gertsch J , Sodi A , Giovannetti E , Macchia M , Minutolo F , Tuccinardi T , Chicca A |
| Ref : Eur Journal of Medicinal Chemistry , 209 :112857 , 2020 |
| Abstract : |
| PubMedSearch : Granchi_2020_Eur.J.Med.Chem_209_112857 |
| PubMedID: 33045662 |
| Gene_locus related to this paper: human-MGLL |
| Title : The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors - Zhu_2020_Bioorg.Med.Chem.Lett_30_127243 |
| Author(s) : Zhu B , Connolly PJ , Zhang YM , McDonnell ME , Bian H , Lin SC , Liu L , Zhang SP , Chevalier KM , Brandt MR , Milligan CM , Flores CM , Macielag MJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 30 :127243 , 2020 |
| Abstract : |
| PubMedSearch : Zhu_2020_Bioorg.Med.Chem.Lett_30_127243 |
| PubMedID: 32527545 |
| Gene_locus related to this paper: human-MGLL |
| Title : Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-((18)F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbo nyl)piperazin-1-yl]pyrrolidin-2-one ([(18)F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase - Hattori_2019_J.Med.Chem_62_2362 |
| Author(s) : Hattori Y , Aoyama K , Maeda J , Arimura N , Takahashi Y , Sasaki M , Fujinaga M , Seki C , Nagai Y , Kawamura K , Yamasaki T , Zhang MR , Higuchi M , Koike T |
| Ref : Journal of Medicinal Chemistry , 62 :2362 , 2019 |
| Abstract : |
| PubMedSearch : Hattori_2019_J.Med.Chem_62_2362 |
| PubMedID: 30753069 |
| Gene_locus related to this paper: human-MGLL |
| Title : Characterisation and localisation of the endocannabinoid system components in the adult human testis - Nielsen_2019_Sci.Rep_9_12866 |
| Author(s) : Nielsen JE , Rolland AD , Rajpert-De Meyts E , Janfelt C , Jorgensen A , Winge SB , Kristensen DM , Juul A , Chalmel F , Jegou B , Skakkebaek NE |
| Ref : Sci Rep , 9 :12866 , 2019 |
| Abstract : |
| PubMedSearch : Nielsen_2019_Sci.Rep_9_12866 |
| PubMedID: 31537814 |
| Gene_locus related to this paper: human-ABHD2 , human-MGLL |
| Title : omega-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase - Dato_2019_Bioorg.Chem__103352 |
| Author(s) : Dato FM , Neudorfl JM , Gutschow M , Goldfuss B , Pietsch M |
| Ref : Bioorg Chem , :103352 , 2019 |
| Abstract : |
| PubMedSearch : Dato_2019_Bioorg.Chem__103352 |
| PubMedID: 31668797 |
| Gene_locus related to this paper: human-MGLL |
| Title : Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton - Chen_2019_J.Med.Chem_62_3336 |
| Author(s) : Chen Z , Mori W , Deng X , Cheng R , Ogasawara D , Zhang G , Schafroth MA , Dahl K , Fu H , Hatori A , Shao T , Zhang Y , Yamasaki T , Zhang X , Rong J , Yu Q , Hu K , Fujinaga M , Xie L , Kumata K , Gou Y , Chen J , Gu S , Bao L , Wang L , Collier TL , Vasdev N , Shao Y , Ma JA , Cravatt BF , Fowler C , Josephson L , Zhang MR , Liang SH |
| Ref : Journal of Medicinal Chemistry , 62 :3336 , 2019 |
| Abstract : |
| PubMedSearch : Chen_2019_J.Med.Chem_62_3336 |
| PubMedID: 30829483 |
| Gene_locus related to this paper: human-MGLL |
| Title : Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors - Poli_2019_J.Enzyme.Inhib.Med.Chem_34_589 |
| Author(s) : Poli G , Lapillo M , Jha V , Mouawad N , Caligiuri I , Macchia M , Minutolo F , Rizzolio F , Tuccinardi T , Granchi C |
| Ref : J Enzyme Inhib Med Chem , 34 :589 , 2019 |
| Abstract : |
| PubMedSearch : Poli_2019_J.Enzyme.Inhib.Med.Chem_34_589 |
| PubMedID: 30696302 |
| Gene_locus related to this paper: human-MGLL |
| Title : Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation - McAllister_2018_J.Med.Chem_61_3008 |
| Author(s) : McAllister LA , Butler CR , Mente S , O'Neil SV , Fonseca KR , Piro JR , Cianfrogna JA , Foley TL , Gilbert AM , Harris AR , Helal CJ , Johnson DS , Montgomery JI , Nason DM , Noell S , Pandit J , Rogers BN , Samad TA , Shaffer CL , da Silva RG , Uccello DP , Webb D , Brodney MA |
| Ref : Journal of Medicinal Chemistry , 61 :3008 , 2018 |
| Abstract : |
| PubMedSearch : McAllister_2018_J.Med.Chem_61_3008 |
| PubMedID: 29498843 |
| Gene_locus related to this paper: human-MGLL |
| Title : Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase - Tyukhtenko_2018_Sci.Rep_8_1719 |
| Author(s) : Tyukhtenko S , Rajarshi G , Karageorgos I , Zvonok N , Gallagher ES , Huang H , Vemuri K , Hudgens JW , Ma X , Nasr ML , Pavlopoulos S , Makriyannis A |
| Ref : Sci Rep , 8 :1719 , 2018 |
| Abstract : |
| PubMedSearch : Tyukhtenko_2018_Sci.Rep_8_1719 |
| PubMedID: 29379013 |
| Gene_locus related to this paper: human-MGLL |
| Title : Identification of lipases with activity towards monoacylglycerol by criterion of conserved cap architectures - Riegler-Berket_2018_Biochim.Biophys.Acta_1863_679 |
| Author(s) : Riegler-Berket L , Leitmeier A , Aschauer P , Dreveny I , Oberer M |
| Ref : Biochimica & Biophysica Acta , 1863 :679 , 2018 |
| Abstract : |
| PubMedSearch : Riegler-Berket_2018_Biochim.Biophys.Acta_1863_679 |
| PubMedID: 29627382 |
| Gene_locus related to this paper: 9bact-TtEst , agrvs-b9jym4 , bac25-mglp , bacsu-cbxnp , human-MGLL , symth-q67mr3 , vibch-VC1974 , yeast-mgll |
| Title : Monoacylglycerol lipase (MAGL) as a promising therapeutic target - Gil-Ordonez_2018_Biochem.Pharmacol_157_18 |
| Author(s) : Gil-Ordonez A , Martin-Fontecha M , Ortega-Gutierrez S , Lopez-Rodriguez ML |
| Ref : Biochemical Pharmacology , 157 :18 , 2018 |
| Abstract : |
| PubMedSearch : Gil-Ordonez_2018_Biochem.Pharmacol_157_18 |
| PubMedID: 30059673 |
| Gene_locus related to this paper: human-MGLL |
| Title : Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors - Aida_2018_J.Med.Chem_61_9205 |
| Author(s) : Aida J , Fushimi M , Kusumoto T , Sugiyama H , Arimura N , Ikeda S , Sasaki M , Sogabe S , Aoyama K , Koike T |
| Ref : Journal of Medicinal Chemistry , 61 :9205 , 2018 |
| Abstract : |
| PubMedSearch : Aida_2018_J.Med.Chem_61_9205 |
| PubMedID: 30251836 |
| Gene_locus related to this paper: human-MGLL |
| Title : Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases - Baggelaar_2017_ACS.Chem.Biol_12_852 |
| Author(s) : Baggelaar MP , van Esbroeck AC , van Rooden EJ , Florea BI , Overkleeft HS , Marsicano G , Chaouloff F , van der Stelt M |
| Ref : ACS Chemical Biology , 12 :852 , 2017 |
| Abstract : |
| PubMedSearch : Baggelaar_2017_ACS.Chem.Biol_12_852 |
| PubMedID: 28106377 |
| Gene_locus related to this paper: human-ABHD4 , human-ABHD6 , human-ABHD12 , human-DAGLA , human-MGLL |
| Title : The role of human monoacylglycerol lipase (hMAGL) binding pocket in breakup of unsaturated phospholipid membranes - Karageorgos_2017_Anal.Biochem_536_90 |
| Author(s) : Karageorgos I , Silin VI , Zvonok N , Marino J , Janero DR , Makriyannis A |
| Ref : Analytical Biochemistry , 536 :90 , 2017 |
| Abstract : |
| PubMedSearch : Karageorgos_2017_Anal.Biochem_536_90 |
| PubMedID: 28822686 |
| Gene_locus related to this paper: human-MGLL |
| Title : Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase - Butler_2017_J.Med.Chem_60_9860 |
| Author(s) : Butler CR , Beck EM , Harris A , Huang Z , McAllister LA , Am Ende CW , Fennell K , Foley TL , Fonseca K , Hawrylik SJ , Johnson DS , Knafels JD , Mente S , Noell GS , Pandit J , Phillips TB , Piro JR , Rogers BN , Samad TA , Wang J , Wan S , Brodney MA |
| Ref : Journal of Medicinal Chemistry , 60 :9860 , 2017 |
| Abstract : |
| PubMedSearch : Butler_2017_J.Med.Chem_60_9860 |
| PubMedID: 29148769 |
| Gene_locus related to this paper: human-MGLL |
| Title : Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus - Parker_2015_Psychopharmacology.(Berl)_232_583 |
| Author(s) : Parker LA , Niphakis MJ , Downey R , Limebeer CL , Rock EM , Sticht MA , Morris H , Abdullah RA , Lichtman AH , Cravatt BF |
| Ref : Psychopharmacology (Berl) , 232 :583 , 2015 |
| Abstract : |
| PubMedSearch : Parker_2015_Psychopharmacology.(Berl)_232_583 |
| PubMedID: 25085768 |
| Gene_locus related to this paper: human-MGLL |
| Title : Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity - Zhang_2015_Hippocampus_25_16 |
| Author(s) : Zhang Z , Wang W , Zhong P , Liu SJ , Long JZ , Zhao L , Gao HQ , Cravatt BF , Liu QS |
| Ref : Hippocampus , 25 :16 , 2015 |
| Abstract : |
| PubMedSearch : Zhang_2015_Hippocampus_25_16 |
| PubMedID: 25131612 |
| Gene_locus related to this paper: human-MGLL |
| Title : Inhibition of monoacylglycerol lipase reduces nicotine withdrawal - Muldoon_2015_Br.J.Pharmacol_172_869 |
| Author(s) : Muldoon PP , Chen J , Harenza JL , Abdullah RA , Sim-Selley LJ , Cravatt BF , Miles MF , Chen X , Lichtman AH , Damaj MI |
| Ref : British Journal of Pharmacology , 172 :869 , 2015 |
| Abstract : |
| PubMedSearch : Muldoon_2015_Br.J.Pharmacol_172_869 |
| PubMedID: 25258021 |
| Gene_locus related to this paper: human-MGLL |
| Title : Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice - Schlosburg_2014_J.Pharmacol.Exp.Ther_350_196 |
| Author(s) : Schlosburg JE , Kinsey SG , Ignatowska-Jankowska B , Ramesh D , Abdullah RA , Tao Q , Booker L , Long JZ , Selley DE , Cravatt BF , Lichtman AH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 350 :196 , 2014 |
| Abstract : |
| PubMedSearch : Schlosburg_2014_J.Pharmacol.Exp.Ther_350_196 |
| PubMedID: 24849924 |
| Gene_locus related to this paper: human-MGLL |
| Title : In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects - Ignatowska-Jankowska_2014_Br.J.Pharmacol_171_1392 |
| Author(s) : Ignatowska-Jankowska BM , Ghosh S , Crowe MS , Kinsey SG , Niphakis MJ , Abdullah RA , Tao Q , ST ON , Walentiny DM , Wiley JL , Cravatt BF , Lichtman AH |
| Ref : British Journal of Pharmacology , 171 :1392 , 2014 |
| Abstract : |
| PubMedSearch : Ignatowska-Jankowska_2014_Br.J.Pharmacol_171_1392 |
| PubMedID: 23848221 |
| Gene_locus related to this paper: human-MGLL |
| Title : Mutation of cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency - Laitinen_2014_Mol.Pharmacol_85_510 |
| Author(s) : Laitinen T , Navia-Paldanius D , Rytilahti R , Marjamaa JJ , Karizkova J , Parkkari T , Pantsar T , Poso A , Laitinen JT , Savinainen JR |
| Ref : Molecular Pharmacology , 85 :510 , 2014 |
| Abstract : |
| PubMedSearch : Laitinen_2014_Mol.Pharmacol_85_510 |
| PubMedID: 24368842 |
| Gene_locus related to this paper: human-MGLL |
| Title : Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL) - Savinainen_2014_Mol.Pharmacol_86_522 |
| Author(s) : Savinainen JR , Kansanen E , Pantsar T , Navia-Paldanius D , Parkkari T , Lehtonen M , Laitinen T , Nevalainen T , Poso A , Levonen AL , Laitinen JT |
| Ref : Molecular Pharmacology , 86 :522 , 2014 |
| Abstract : |
| PubMedSearch : Savinainen_2014_Mol.Pharmacol_86_522 |
| PubMedID: 25140003 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
| Title : Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice - Ramesh_2013_Neuropsychopharmacology_38_1039 |
| Author(s) : Ramesh D , Gamage TF , Vanuytsel T , Owens RA , Abdullah RA , Niphakis MJ , Shea-Donohue T , Cravatt BF , Lichtman AH |
| Ref : Neuropsychopharmacology , 38 :1039 , 2013 |
| Abstract : |
| PubMedSearch : Ramesh_2013_Neuropsychopharmacology_38_1039 |
| PubMedID: 23303065 |
| Gene_locus related to this paper: human-MGLL |
| Title : Monoacylglycerol lipase controls endocannabinoid and eicosanoid signaling and hepatic injury in mice - Cao_2013_Gastroenterology_144_808 |
| Author(s) : Cao Z , Mulvihill MM , Mukhopadhyay P , Xu H , Erdelyi K , Hao E , Holovac E , Hasko G , Cravatt BF , Nomura DK , Pacher P |
| Ref : Gastroenterology , 144 :808 , 2013 |
| Abstract : |
| PubMedSearch : Cao_2013_Gastroenterology_144_808 |
| PubMedID: 23295443 |
| Gene_locus related to this paper: human-MGLL |
| Title : Chemical probes of endocannabinoid metabolism - Blankman_2013_Pharmacol.Rev_65_849 |
| Author(s) : Blankman JL , Cravatt BF |
| Ref : Pharmacol Rev , 65 :849 , 2013 |
| Abstract : |
| PubMedSearch : Blankman_2013_Pharmacol.Rev_65_849 |
| PubMedID: 23512546 |
| Gene_locus related to this paper: human-MGLL |
| Title : The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model - Ghosh_2013_Life.Sci_92_498 |
| Author(s) : Ghosh S , Wise LE , Chen Y , Gujjar R , Mahadevan A , Cravatt BF , Lichtman AH |
| Ref : Life Sciences , 92 :498 , 2013 |
| Abstract : |
| PubMedSearch : Ghosh_2013_Life.Sci_92_498 |
| PubMedID: 22749865 |
| Gene_locus related to this paper: human-MGLL |
| Title : Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects - Kinsey_2013_J.Pharmacol.Exp.Ther_345_492 |
| Author(s) : Kinsey SG , Wise LE , Ramesh D , Abdullah R , Selley DE , Cravatt BF , Lichtman AH |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 345 :492 , 2013 |
| Abstract : |
| PubMedSearch : Kinsey_2013_J.Pharmacol.Exp.Ther_345_492 |
| PubMedID: 23412396 |
| Gene_locus related to this paper: human-MGLL |
| Title : Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase - Aaltonen_2013_Chem.Biol_20_379 |
| Author(s) : Aaltonen N , Savinainen JR , Ribas CR , Ronkko J , Kuusisto A , Korhonen J , Navia-Paldanius D , Hayrinen J , Takabe P , Kasnanen H , Pantsar T , Laitinen T , Lehtonen M , Pasonen-Seppanen S , Poso A , Nevalainen T , Laitinen JT |
| Ref : Chemical Biology , 20 :379 , 2013 |
| Abstract : |
| PubMedSearch : Aaltonen_2013_Chem.Biol_20_379 |
| PubMedID: 23521796 |
| Gene_locus related to this paper: human-MGLL |
| Title : 1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling - Kasnanen_2013_Eur.J.Pharm.Sci_49_423 |
| Author(s) : Kasnanen H , Minkkila A , Taupila S , Patel JZ , Parkkari T , Lahtela-Kakkonen M , Saario SM , Nevalainen T , Poso A |
| Ref : Eur J Pharm Sci , 49 :423 , 2013 |
| Abstract : |
| PubMedSearch : Kasnanen_2013_Eur.J.Pharm.Sci_49_423 |
| PubMedID: 23557840 |
| Gene_locus related to this paper: human-MGLL |
| Title : Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors - Niphakis_2013_ACS.Chem.Neurosci_4_1322 |
| Author(s) : Niphakis MJ , Cognetta AB, 3rd , Chang JW , Buczynski MW , Parsons LH , Byrne F , Burston JJ , Chapman V , Cravatt BF |
| Ref : ACS Chem Neurosci , 4 :1322 , 2013 |
| Abstract : |
| PubMedSearch : Niphakis_2013_ACS.Chem.Neurosci_4_1322 |
| PubMedID: 23731016 |
| Gene_locus related to this paper: human-MGLL |
| Title : Monoacylglycerol lipase - a target for drug development? - Fowler_2012_Br.J.Pharmacol_166_1568 |
| Author(s) : Fowler CJ |
| Ref : British Journal of Pharmacology , 166 :1568 , 2012 |
| Abstract : |
| PubMedSearch : Fowler_2012_Br.J.Pharmacol_166_1568 |
| PubMedID: 22428756 |
| Gene_locus related to this paper: human-MGLL |
| Title : Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates - Chang_2012_Chem.Biol_19_579 |
| Author(s) : Chang JW , Niphakis MJ , Lum KM , Cognetta AB, 3rd , Wang C , Matthews ML , Niessen S , Buczynski MW , Parsons LH , Cravatt BF |
| Ref : Chemical Biology , 19 :579 , 2012 |
| Abstract : |
| PubMedSearch : Chang_2012_Chem.Biol_19_579 |
| PubMedID: 22542104 |
| Gene_locus related to this paper: human-MGLL |
| Title : Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL) - Karageorgos_2012_ACS.Chem.Neurosci_3_393 |
| Author(s) : Karageorgos I , Zvonok N , Janero DR , Vemuri VK , Shukla V , Wales TE , Engen JR , Makriyannis A |
| Ref : ACS Chem Neurosci , 3 :393 , 2012 |
| Abstract : |
| PubMedSearch : Karageorgos_2012_ACS.Chem.Neurosci_3_393 |
| PubMedID: 22860208 |
| Gene_locus related to this paper: human-MGLL |
| Title : The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors - Savinainen_2012_Acta.Physiol.(Oxf)_204_267 |
| Author(s) : Savinainen JR , Saario SM , Laitinen JT |
| Ref : Acta Physiol (Oxf) , 204 :267 , 2012 |
| Abstract : |
| PubMedSearch : Savinainen_2012_Acta.Physiol.(Oxf)_204_267 |
| PubMedID: 21418147 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
| Title : Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice - Wise_2012_ACS.Chem.Neurosci_3_369 |
| Author(s) : Wise LE , Long KA , Abdullah RA , Long JZ , Cravatt BF , Lichtman AH |
| Ref : ACS Chem Neurosci , 3 :369 , 2012 |
| Abstract : |
| PubMedSearch : Wise_2012_ACS.Chem.Neurosci_3_369 |
| PubMedID: 22860205 |
| Gene_locus related to this paper: human-MGLL |
| Title : O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors - Niphakis_2012_ACS.Chem.Neurosci_3_418 |
| Author(s) : Niphakis MJ , Johnson DS , Ballard TE , Stiff C , Cravatt BF |
| Ref : ACS Chem Neurosci , 3 :418 , 2012 |
| Abstract : |
| PubMedSearch : Niphakis_2012_ACS.Chem.Neurosci_3_418 |
| PubMedID: 22860211 |
| Gene_locus related to this paper: human-MGLL |
| Title : Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 A resolution - Schalk-Hihi_2011_Protein.Sci_20_670 |
| Author(s) : Schalk-Hihi C , Schubert C , Alexander R , Bayoumy S , Clemente JC , Deckman I , Desjarlais RL , Dzordzorme KC , Flores CM , Grasberger B , Kranz JK , Lewandowski F , Liu L , Ma H , Maguire D , Macielag MJ , McDonnell ME , Mezzasalma Haarlander T , Miller R , Milligan C , Reynolds C , Kuo LC |
| Ref : Protein Science , 20 :670 , 2011 |
| Abstract : |
| PubMedSearch : Schalk-Hihi_2011_Protein.Sci_20_670 |
| PubMedID: 21308848 |
| Gene_locus related to this paper: human-MGLL |
| Title : Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice - Pan_2011_J.Neurosci_31_13420 |
| Author(s) : Pan B , Wang W , Zhong P , Blankman JL , Cravatt BF , Liu QS |
| Ref : Journal of Neuroscience , 31 :13420 , 2011 |
| Abstract : |
| PubMedSearch : Pan_2011_J.Neurosci_31_13420 |
| PubMedID: 21940435 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum - Zhong_2011_J.Physiol_589_4847 |
| Author(s) : Zhong P , Pan B , Gao XP , Blankman JL , Cravatt BF , Liu QS |
| Ref : Journal de Physiologie , 589 :4847 , 2011 |
| Abstract : |
| PubMedSearch : Zhong_2011_J.Physiol_589_4847 |
| PubMedID: 21911610 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling - Labar_2010_Chembiochem_11_218 |
| Author(s) : Labar G , Bauvois C , Borel F , Ferrer JL , Wouters J , Lambert DM |
| Ref : Chembiochem , 11 :218 , 2010 |
| Abstract : |
| PubMedSearch : Labar_2010_Chembiochem_11_218 |
| PubMedID: 19957260 |
| Gene_locus related to this paper: human-MGLL |
| Title : Structural basis for human monoglyceride lipase inhibition - Bertrand_2010_J.Mol.Biol_396_663 |
| Author(s) : Bertrand T , Auge F , Houtmann J , Rak A , Vallee F , Mikol V , Berne PF , Michot N , Cheuret D , Hoornaert C , Mathieu M |
| Ref : Journal of Molecular Biology , 396 :663 , 2010 |
| Abstract : |
| PubMedSearch : Bertrand_2010_J.Mol.Biol_396_663 |
| PubMedID: 19962385 |
| Gene_locus related to this paper: human-MGLL |
| Title : Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae - Heier_2010_Biochim.Biophys.Acta_1801_1063 |
| Author(s) : Heier C , Taschler U , Rengachari S , Oberer M , Wolinski H , Natter K , Kohlwein SD , Leber R , Zimmermann R |
| Ref : Biochimica & Biophysica Acta , 1801 :1063 , 2010 |
| Abstract : |
| PubMedSearch : Heier_2010_Biochim.Biophys.Acta_1801_1063 |
| PubMedID: 20554061 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL , yeast-mgll |
| Title : Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis - Nomura_2010_Cell_140_49 |
| Author(s) : Nomura DK , Long JZ , Niessen S , Hoover HS , Ng SW , Cravatt BF |
| Ref : Cell , 140 :49 , 2010 |
| Abstract : |
| PubMedSearch : Nomura_2010_Cell_140_49 |
| PubMedID: 20079333 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level - Harismendy_2010_Genome.Biol_11_R118 |
| Author(s) : Harismendy O , Bansal V , Bhatia G , Nakano M , Scott M , Wang X , Dib C , Turlotte E , Sipe JC , Murray SS , Deleuze JF , Bafna V , Topol EJ , Frazer KA |
| Ref : Genome Biol , 11 :R118 , 2010 |
| Abstract : |
| PubMedSearch : Harismendy_2010_Genome.Biol_11_R118 |
| PubMedID: 21118518 |
| Gene_locus related to this paper: human-MGLL |
| Title : Characterization of binding properties of monoglyceride lipase inhibitors by a versatile fluorescence-based technique - Savinainen_2010_Anal.Biochem_399_132 |
| Author(s) : Savinainen JR , Yoshino M , Minkkila A , Nevalainen T , Laitinen JT |
| Ref : Analytical Biochemistry , 399 :132 , 2010 |
| Abstract : |
| PubMedSearch : Savinainen_2010_Anal.Biochem_399_132 |
| PubMedID: 20005861 |
| Gene_locus related to this paper: human-MGLL |
| Title : Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons - Straiker_2009_Mol.Pharmacol_76_1220 |
| Author(s) : Straiker A , Hu SS , Long JZ , Arnold A , Wager-Miller J , Cravatt BF , Mackie K |
| Ref : Molecular Pharmacology , 76 :1220 , 2009 |
| Abstract : |
| PubMedSearch : Straiker_2009_Mol.Pharmacol_76_1220 |
| PubMedID: 19767452 |
| Gene_locus related to this paper: human-MGLL |
| Title : CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay - Muccioli_2008_Chembiochem_9_2704 |
| Author(s) : Muccioli GG , Labar G , Lambert DM |
| Ref : Chembiochem , 9 :2704 , 2008 |
| Abstract : |
| PubMedSearch : Muccioli_2008_Chembiochem_9_2704 |
| PubMedID: 18855964 |
| Gene_locus related to this paper: human-MGLL |
| Title : A fluorescence-based assay for monoacylglycerol lipase compatible with inhibitor screening - Wang_2008_Assay.Drug.Dev.Technol_6_387 |
| Author(s) : Wang Y , Chanda P , Jones PG , Kennedy JD |
| Ref : Assay Drug Dev Technol , 6 :387 , 2008 |
| Abstract : |
| PubMedSearch : Wang_2008_Assay.Drug.Dev.Technol_6_387 |
| PubMedID: 18452392 |
| Gene_locus related to this paper: human-MGLL |
| Title : Disulfiram is an inhibitor of human purified monoacylglycerol lipase, the enzyme regulating 2-arachidonoylglycerol signaling - Labar_2007_Chembiochem_8_1293 |
| Author(s) : Labar G , Bauvois C , Muccioli GG , Wouters J , Lambert DM |
| Ref : Chembiochem , 8 :1293 , 2007 |
| Abstract : |
| PubMedSearch : Labar_2007_Chembiochem_8_1293 |
| PubMedID: 17579916 |
| Gene_locus related to this paper: human-MGLL |
| Title : Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase - Vila_2007_Biochemistry_46_9578 |
| Author(s) : Vila A , Rosengarth A , Piomelli D , Cravatt B , Marnett LJ |
| Ref : Biochemistry , 46 :9578 , 2007 |
| Abstract : |
| PubMedSearch : Vila_2007_Biochemistry_46_9578 |
| PubMedID: 17649977 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol - Blankman_2007_Chem.Biol_14_1347 |
| Author(s) : Blankman JL , Simon GM , Cravatt BF |
| Ref : Chemical Biology , 14 :1347 , 2007 |
| Abstract : |
| PubMedSearch : Blankman_2007_Chem.Biol_14_1347 |
| PubMedID: 18096503 |
| Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL |
| Title : Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene - Karlsson_2001_Gene_272_11 |
| Author(s) : Karlsson M , Reue K , Xia YR , Lusis AJ , Langin D , Tornqvist H , Holm C |
| Ref : Gene , 272 :11 , 2001 |
| Abstract : |
| PubMedSearch : Karlsson_2001_Gene_272_11 |
| PubMedID: 11470505 |
| Gene_locus related to this paper: human-MGLL , mouse-MGLL |
| Title : A novel poxvirus gene and its human homolog are similar to an E. coli lysophospholipase - Wall_1997_Virus.Res_52_157 |
| Author(s) : Wall EM , Cao J , Chen N , Buller RM , Upton C |
| Ref : Virus Res , 52 :157 , 1997 |
| Abstract : |
| PubMedSearch : Wall_1997_Virus.Res_52_157 |
| PubMedID: 9495531 |
| Gene_locus related to this paper: cowvi-M5L , human-MGLL |