human-MGLL

Homo sapiens (Human) Monoglyceride lipase (MAGL) lysophospholipase homolog

Comment

Human monoacylglycerol lipase (hMAGL Monoglyceride lipase MGLL) converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth

Relationship

Family : Monoglyceridelipase_lysophospholip

Block : X

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Molecular evidence

No mutation

6AX1 - Structure of human monoacylglycerol lipase bound to a covalent inhibitor 9F8A - Crystal structure of human monoacylglycerol lipase in complex with compound 7a 9F8B - Crystal structure of human monoacylglycerol lipase in complex with compound 7n 9F8C - Crystal structure of human monoacylglycerol lipase in complex with compound 7m 9F8D - Crystal structure of human monoacylglycerol lipase in complex with compound 7l 8RVF - Crystal structure of human monoacylglycerol lipase in complex with compound 5 8PTC - Crystal structure of human monoacylglycerol lipase in complex with compound 5d 8PTQ - Crystal structure of human monoacylglycerol lipase in complex with compound 5l 8PTR - Crystal structure of human monoacylglycerol lipase in complex with compound 5r 8AQF - Crystal structure of human monoacylglycerol lipase in complex with compound LEI-515 7L4W - Crystal structure of human monoacylglycerol lipase in complex with compound SCHEMBL19421059 7L50 - Crystal structure of human monoacylglycerol lipase in complex with compound SCHEMBL19421119 7L4U - Crystal structure of human monoacylglycerol lipase in complex with compound XP7-7L4U 7L4T - Crystal structure of human monoacylglycerol lipase in complex with compound SCHEMBL19834081 5ZUN - Crystal structure of human monoacylglycerol lipase in complex with compound 3l 6BQ0 - Structure of human monoacylglycerol lipase bound to PF-06795071 a covalent inhibitor 3PE6 - Crystal Structure of a soluble form of human MGLL in complex with an inhibitor 4UUQ - Crystal structure of human mono-glyceride lipase in complex with SAR127303 3JWE - Crystal structure of human Mono glyceride lipase in complex with SAR629 3JW8 - Crystal structure of human Mono glyceride lipase 7ZPG - Crystal structure of human monoglyceride lipase with ligand MAGLi-432 7PRM - Crystal structure of human monoglyceride lipase with compound 13, YH149 3HJU - Crystal structure of human monoglyceride lipase

No kinetic

No disease

Sequence

Peptide

MPEESSPRRT PQSIPYQDLP HLVNADGQYL FCRYWKPTGT PKALIFVSHG AGEHSGRYEE LARMLMGLDL LVFAHDHVGH GQSEGERMVV SDFHVFVRDV LQHVDSMQKD YPGLPVFLLG HSMGGAIAIL TAAERPGHFA GMVLISPLVL ANPESATTFK VLAAKVLNLV LPNLSLGPID SSVLSRNKTE VDIYNSDPLI CRAGLKVCFG IQLLNAVSRV ERALPKLTVP FLLLQGSADR LCDSKGAYLL MELAKSQDKT LKIYEGAYHV LHKELPEVTN SVFHEINMWV SQRTATAGTA SPP

References (88)

Title : Binding of the monoacylglycerol lipase (MAGL) radiotracer [(3)H]T-401 in the rat brain after status epilepticus - Mikkelsen_2024_Neurochem.Int__105717
Author(s) : Mikkelsen JD , Aripaka SS , Egilmez CB , Pazarlar BA
Ref : Neurochem Int , :105717 , 2024
PubMedID: 38447759
Gene_locus related to this paper: human-MGLL

Title : Elevating levels of the endocannabinoid 2-arachidonoylglycerol blunts opioid reward but not analgesia - Martinez-Rivera_2024_bioRxiv__
Author(s) : Martinez-Rivera A , Fetcho RN , Birmingham L , Jiu JX , Yang R , Foord C , Scala-Chavez D , Mekawy N , Pleil K , Pickel VM , Liston C , Castorena CM , Levitz J , Pan YX , Briand LA , Rajadhyaksha AM , Lee FS
Ref : Biorxiv , : , 2024
PubMedID: 38766079
Gene_locus related to this paper: human-MGLL

Title : MAGL protects against renal fibrosis through inhibiting tubular cell lipotoxicity - Zhou_2024_Theranostics_14_1583
Author(s) : Zhou S , Ling X , Zhu J , Liang Y , Feng Q , Xie C , Li J , Chen Q , Chen S , Miao J , Zhang M , Li Z , Shen W , Li X , Wu Q , Wang X , Liu R , Wang C , Hou FF , Kong Y , Liu Y , Zhou L
Ref : Theranostics , 14 :1583 , 2024
PubMedID: 38389852
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization - Butini_2024_J.Med.Chem__
Author(s) : Butini S , Grether U , Jung KM , Ligresti A , Allara M , Postmus AGJ , Maramai S , Brogi S , Papa A , Carullo G , Sykes D , Veprintsev D , Federico S , Grillo A , Di Guglielmo B , Ramunno A , Stevens AF , Heer D , Lamponi S , Gemma S , Benz J , Di Marzo V , van der Stelt M , Piomelli D , Campiani G
Ref : Journal of Medicinal Chemistry , : , 2024
PubMedID: 38241614
Gene_locus related to this paper: human-MGLL

Title : Inhibition of Monoacylglycerol Lipase Decreases Angiogenic Features of Endothelial Cells via Release of Tissue Inhibitor of Metalloproteinase-1 from Lung Cancer Cells - Wittig_2023_Cells_12_1757
Author(s) : Wittig F , Henkel L , Pruser JL , Merkord J , Ramer R , Hinz B
Ref : Cells , 12 :1757 , 2023
PubMedID: 37443791
Gene_locus related to this paper: human-MGLL

Title : ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache - Liktor-Busa_2023_Front.Pain.Res.(Lausanne)_4_1171188
Author(s) : Liktor-Busa E , Levine AA , Palomino SM , Singh S , Wahl J , Vanderah TW , Stella N , Largent-Milnes TM
Ref : Front Pain Res (Lausanne) , 4 :1171188 , 2023
PubMedID: 37287623
Gene_locus related to this paper: human-ABHD6 , human-MGLL

Title : Monoglyceride Lipase Deficiency Is Associated with Altered Thrombogenesis in Mice - Goeritzer_2023_Int.J.Mol.Sci_24_
Author(s) : Goeritzer M , Kuentzel KB , Beck S , Korbelius M , Rainer S , Bradic I , Kolb D , Mussbacher M , Schrottmaier WC , Assinger A , Schlagenhauf A , Rost R , Gottschalk B , Eichmann TO , Zullig T , Graier WF , Vujic N , Kratky D
Ref : Int J Mol Sci , 24 : , 2023
PubMedID: 36834530
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Novel MAGL Inhibitors Alleviate LPS-Induced Acute Kidney Injury by Inhibiting NLRP3 Inflammatory Vesicles, Modulating Intestinal Flora, Repairing the Intestinal Barrier, and Interfering with Serum Metabolism - Xiang_2023_Molecules_28_7245
Author(s) : Xiang H , Wang Y , Yang L , Liu M , Sun C , Gu Y , Yao J
Ref : Molecules , 28 : , 2023
PubMedID: 37959665
Gene_locus related to this paper: human-MGLL

Title : MAGL inhibition relieves synovial inflammation and pain via regulating NOX4-Nrf2 redox balance in osteoarthritis - Li_2023_Free.Radic.Biol.Med_208_13
Author(s) : Li X , Tao H , Zhou J , Zhang L , Shi Y , Zhang C , Sun W , Chu M , Chen K , Gu C , Yang X , Geng D , Hao Y
Ref : Free Radic Biol Med , 208 :13 , 2023
PubMedID: 37516370
Gene_locus related to this paper: human-MGLL

Title : IL-8-induced CXCR2 down-regulation in circulating monocytes in hepatocellular carcinoma is partially dependent on MAGL - Liu_2023_BMC.Cancer_23_626
Author(s) : Liu CZ , Liu XB , Sun J , Yu CQ , Yao JC , Liu Z , Hao JC
Ref : BMC Cancer , 23 :626 , 2023
PubMedID: 37403022
Gene_locus related to this paper: human-MGLL

Title : Potent dual MAGL\/FAAH inhibitor AKU-005 engages endocannabinoids to diminish meningeal nociception implicated in migraine pain - Della Pietra_2023_J.Headache.Pain_24_38
Author(s) : Della Pietra A , Krivoshein G , Ivanov K , Giniatullina R , Jyrkkanen HK , Leinonen V , Lehtonen M , van den Maagdenberg A , Savinainen J , Giniatullin R
Ref : J Headache Pain , 24 :38 , 2023
PubMedID: 37038131
Gene_locus related to this paper: human-MGLL

Title : Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain - He_2022_Eur.J.Med.Chem_243_114750
Author(s) : He Y , Grether U , Taddio MF , Meier C , Keller C , Edelmann MR , Honer M , Huber S , Wittwer MB , Heer D , Richter H , Collin L , Hug MN , Hilbert M , Postmus AGJ , Stevens AF , van der Stelt M , Kramer SD , Schibli R , Mu L , Gobbi LC
Ref : Eur Journal of Medicinal Chemistry , 243 :114750 , 2022
PubMedID: 36137365
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging - He_2022_J.Med.Chem_65_2191
Author(s) : He Y , Schild M , Grether U , Benz J , Leibrock L , Heer D , Topp A , Collin L , Kuhn B , Wittwer M , Keller C , Gobbi LC , Schibli R , Mu L
Ref : Journal of Medicinal Chemistry , 65 :2191 , 2022
PubMedID: 35089028
Gene_locus related to this paper: human-MGLL

Title : A potent and selective inhibitor for the modulation of MAGL activity in the neurovasculature - Kemble_2022_PLoS.One_17_e0268590
Author(s) : Kemble AM , Hornsperger B , Ruf I , Richter H , Benz J , Kuhn B , Heer D , Wittwer M , Engelhardt B , Grether U , Collin L
Ref : PLoS ONE , 17 :e0268590 , 2022
PubMedID: 36084029
Gene_locus related to this paper: human-MGLL

Title : A novel monoacylglycerol lipase-targeted (18)F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network - Cheng_2022_Acta.Pharmacol.Sin__
Author(s) : Cheng R , Fujinaga M , Yang J , Rong J , Haider A , Ogasawara D , Van RS , Shao T , Chen Z , Zhang X , Calderon Leon ER , Zhang Y , Mori W , Kumata K , Yamasaki T , Xie L , Sun S , Wang L , Ran C , Shao Y , Cravatt B , Josephson L , Zhang MR , Liang SH
Ref : Acta Pharmacol Sin , : , 2022
PubMedID: 35513432
Gene_locus related to this paper: human-MGLL

Title : Inhibiting Endocannabinoid Hydrolysis as Emerging Analgesic Strategy Targeting a Spectrum of Ion Channels Implicated in Migraine Pain - Della Pietra_2022_Int.J.Mol.Sci_23_
Author(s) : Della Pietra A , Savinainen J , Giniatullin R
Ref : Int J Mol Sci , 23 : , 2022
PubMedID: 35457225
Gene_locus related to this paper: human-MGLL

Title : MAGL inhibitor NanoMicellar formulation (MAGL-NanoMicellar) for the development of an antiglaucoma eye drop - Chetoni_2022_Int.J.Pharm__122078
Author(s) : Chetoni P , Burgalassi S , Zucchetti E , Granchi C , Minutolo F , Tampucci S , Monti D
Ref : Int J Pharm , :122078 , 2022
PubMedID: 35932931
Gene_locus related to this paper: human-MGLL

Title : Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency - Galvani_2022_J.Chem.Inf.Model__
Author(s) : Galvani F , Scalvini L , Rivara S , Lodola A , Mor M
Ref : J Chem Inf Model , : , 2022
PubMedID: 35580195
Gene_locus related to this paper: human-MGLL

Title : Inhibition of triple negative breast cancer-associated inflammation, tumor growth and brain colonization by targeting monoacylglycerol lipase - Benchama_2022_Sci.Rep_12_5328
Author(s) : Benchama O , Tyukhtenko S , Malamas MS , Williams MK , Makriyannis A , Avraham HK
Ref : Sci Rep , 12 :5328 , 2022
PubMedID: 35351947
Gene_locus related to this paper: human-MGLL

Title : First-in-human in vivo undefined imaging and quantification of monoacylglycerol lipase in the brain: a PET study with (18)F-T-401 - Takahata_2022_Eur.J.Nucl.Med.Mol.Imaging__
Author(s) : Takahata K , Seki C , Kimura Y , Kubota M , Ichise M , Sano Y , Yamamoto Y , Tagai K , Shimada H , Kitamura S , Matsuoka K , Endo H , Shinotoh H , Kawamura K , Zhang MR , Takado Y , Higuchi M
Ref : Eur J Nucl Med Mol Imaging , : , 2022
PubMedID: 35022846
Gene_locus related to this paper: human-MGLL

Title : Research progress on FASN and MGLL in the regulation of abnormal lipid metabolism and the relationship between tumor invasion and metastasis - Zhang_2021_Front.Med__
Author(s) : Zhang J , Song Y , Shi Q , Fu L
Ref : Front Med , : , 2021
PubMedID: 33973101
Gene_locus related to this paper: human-FASN , human-MGLL

Title : Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex - Pavon_2021_Neurobiol.Stress_14_100293
Author(s) : Pavon FJ , Polis IY , Stouffer DG , Cravatt BF , Roberto M , Martin-Fardon R , Rodriguez de Fonseca F , Parsons LH , Serrano A
Ref : Neurobiol Stress , 14 :100293 , 2021
PubMedID: 33490317
Gene_locus related to this paper: human-MGLL

Title : Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold - Rong_2021_J.Med.Chem__
Author(s) : Rong J , Mori W , Xia X , Schafroth MA , Zhao C , Van RS , Yamasaki T , Chen J , Xiao Z , Haider A , Ogasawara D , Hiraishi A , Shao T , Zhang Y , Chen Z , Pang F , Hu K , Xie L , Fujinaga M , Kumata K , Gou Y , Fang Y , Gu S , Wei H , Bao L , Xu H , Collier TL , Shao Y , Carson RE , Cravatt BF , Wang L , Zhang MR , Liang SH
Ref : Journal of Medicinal Chemistry , : , 2021
PubMedID: 34569803
Gene_locus related to this paper: human-MGLL

Title : Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat - League_2021_Front.Neurol_12_651272
Author(s) : League AF , Gorman BL , Hermes DJ , Johnson CT , Jacobs IR , Yadav-Samudrala BJ , Poklis JL , Niphakis MJ , Cravatt BF , Lichtman AH , Ignatowska-Jankowska BM , Fitting S
Ref : Front Neurol , 12 :651272 , 2021
PubMedID: 34484091
Gene_locus related to this paper: human-MGLL

Title : The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB(1) Cannabinoid Receptor - Pruser_2021_Mol.Cancer.Ther_20_787
Author(s) : Pruser JL , Ramer R , Wittig F , Ivanov I , Merkord J , Hinz B
Ref : Mol Cancer Ther , 20 :787 , 2021
PubMedID: 33632876
Gene_locus related to this paper: human-MGLL

Title : Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl Moiety - Ikeda_2021_J.Med.Chem__
Author(s) : Ikeda S , Sugiyama H , Tokuhara H , Murakami M , Nakamura M , Oguro Y , Aida J , Morishita N , Sogabe S , Dougan DR , Gay SC , Qin L , Arimura N , Takahashi Y , Sasaki M , Kamada Y , Aoyama K , Kimoto K , Kamata M
Ref : Journal of Medicinal Chemistry , : , 2021
PubMedID: 34328319
Gene_locus related to this paper: human-MGLL

Title : 1-, 2- and 3-AG as substrates of the endocannabinoid enzymes and endogenous ligands of the cannabinoid receptor 1 - Farah_2021_Biochem.Biophys.Res.Commun_591_31
Author(s) : Farah SI , Hilston S , Tran N , Zvonok N , Makriyannis A
Ref : Biochemical & Biophysical Research Communications , 591 :31 , 2021
PubMedID: 34995983
Gene_locus related to this paper: human-ABHD6 , human-MGLL

Title : Development of a highly-specific (18)F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping - Chen_2021_Acta.Pharm.Sin.B_11_1686
Author(s) : Chen Z , Mori W , Rong J , Schafroth MA , Shao T , Van RS , Ogasawara D , Yamasaki T , Hiraishi A , Hatori A , Chen J , Zhang Y , Hu K , Fujinaga M , Sun J , Yu Q , Collier TL , Shao Y , Cravatt BF , Josephson L , Zhang MR , Liang SH
Ref : Acta Pharm Sin B , 11 :1686 , 2021
PubMedID: 34221877
Gene_locus related to this paper: human-MGLL

Title : Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening - Xiong_2021_Bioorg.Med.Chem.Lett__127986
Author(s) : Xiong F , Ding X , Zhang H , Luo X , Chen K , Jiang H , Luo C , Xu H
Ref : Bioorganic & Medicinal Chemistry Lett , :127986 , 2021
PubMedID: 33766770
Gene_locus related to this paper: human-MGLL

Title : Conformational gating, dynamics and allostery in human monoacylglycerol lipase - Tyukhtenko_2020_Sci.Rep_10_18531
Author(s) : Tyukhtenko S , Ma X , Rajarshi G , Karageorgos I , Anderson KW , Hudgens JW , Guo JJ , Nasr ML , Zvonok N , Vemuri K , Wagner G , Makriyannis A
Ref : Sci Rep , 10 :18531 , 2020
PubMedID: 33116203
Gene_locus related to this paper: human-MGLL

Title : Termination of acute stress response by the endocannabinoid system is regulated through LSD1-mediated transcriptional repression of 2-AG hydrolases ABHD6 and MAGL - Longaretti_2020_J.Neurochem__e15000
Author(s) : Longaretti A , Forastieri C , Gabaglio M , Rubino T , Battaglioli E , Rusconi F
Ref : Journal of Neurochemistry , :e15000 , 2020
PubMedID: 32141088
Gene_locus related to this paper: human-ABHD6 , human-MGLL , mouse-ABHD6 , mouse-MGLL

Title : The novel MAGL inhibitor MJN110 enhances responding to reward-predictive incentive cues by activation of CB1 receptors - Feja_2020_Neuropharmacol_162_107814
Author(s) : Feja M , Leigh MPK , Baindur AN , McGraw JJ , Wakabayashi KT , Cravatt BF , Bass CE
Ref : Neuropharmacology , 162 :107814 , 2020
PubMedID: 31628934
Gene_locus related to this paper: human-MGLL

Title : The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain - Thompson_2020_J.Pharmacol.Exp.Ther_373_230
Author(s) : Thompson AL , Grenald SA , Ciccone HA , BassiriRad N , Niphakis MJ , Cravatt BF , Largent-Milnes TM , Vanderah TW
Ref : Journal of Pharmacology & Experimental Therapeutics , 373 :230 , 2020
PubMedID: 32054717
Gene_locus related to this paper: human-MGLL

Title : Monoglyceride lipase mediates tumor-suppressive effects by promoting degradation of X-linked inhibitor of apoptosis protein - Liu_2020_Cell.Death.Differ__
Author(s) : Liu R , Wang X , Curtiss C , Sheikh MS , Huang Y
Ref : Cell Death Differ , : , 2020
PubMedID: 32376875
Gene_locus related to this paper: human-MGLL

Title : Inhibition of monoacylglycerol lipase reduces nicotine reward in the conditioned place preference test in male mice - Muldoon_2020_Neuropharmacol__108170
Author(s) : Muldoon PP , Akinola LS , Schlosburg JE , Lichtman AH , Sim-Selley LJ , Mahadevan A , Cravatt BF , Damaj MI
Ref : Neuropharmacology , :108170 , 2020
PubMedID: 32479813
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors - Granchi_2020_Eur.J.Med.Chem_209_112857
Author(s) : Granchi C , Bononi G , Ferrisi R , Gori E , Mantini G , Glasmacher S , Poli G , Palazzolo S , Caligiuri I , Rizzolio F , Canzonieri V , Perin T , Gertsch J , Sodi A , Giovannetti E , Macchia M , Minutolo F , Tuccinardi T , Chicca A
Ref : Eur Journal of Medicinal Chemistry , 209 :112857 , 2020
PubMedID: 33045662
Gene_locus related to this paper: human-MGLL

Title : The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors - Zhu_2020_Bioorg.Med.Chem.Lett_30_127243
Author(s) : Zhu B , Connolly PJ , Zhang YM , McDonnell ME , Bian H , Lin SC , Liu L , Zhang SP , Chevalier KM , Brandt MR , Milligan CM , Flores CM , Macielag MJ
Ref : Bioorganic & Medicinal Chemistry Lett , 30 :127243 , 2020
PubMedID: 32527545
Gene_locus related to this paper: human-MGLL

Title : Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-((18)F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbo nyl)piperazin-1-yl]pyrrolidin-2-one ([(18)F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase - Hattori_2019_J.Med.Chem_62_2362
Author(s) : Hattori Y , Aoyama K , Maeda J , Arimura N , Takahashi Y , Sasaki M , Fujinaga M , Seki C , Nagai Y , Kawamura K , Yamasaki T , Zhang MR , Higuchi M , Koike T
Ref : Journal of Medicinal Chemistry , 62 :2362 , 2019
PubMedID: 30753069
Gene_locus related to this paper: human-MGLL

Title : Characterisation and localisation of the endocannabinoid system components in the adult human testis - Nielsen_2019_Sci.Rep_9_12866
Author(s) : Nielsen JE , Rolland AD , Rajpert-De Meyts E , Janfelt C , Jorgensen A , Winge SB , Kristensen DM , Juul A , Chalmel F , Jegou B , Skakkebaek NE
Ref : Sci Rep , 9 :12866 , 2019
PubMedID: 31537814
Gene_locus related to this paper: human-ABHD2 , human-MGLL

Title : omega-Quinazolinonylalkyl aryl ureas as reversible inhibitors of monoacylglycerol lipase - Dato_2019_Bioorg.Chem__103352
Author(s) : Dato FM , Neudorfl JM , Gutschow M , Goldfuss B , Pietsch M
Ref : Bioorg Chem , :103352 , 2019
PubMedID: 31668797
Gene_locus related to this paper: human-MGLL

Title : Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a Tail Switching Strategy on a Piperazinyl Azetidine Skeleton - Chen_2019_J.Med.Chem_62_3336
Author(s) : Chen Z , Mori W , Deng X , Cheng R , Ogasawara D , Zhang G , Schafroth MA , Dahl K , Fu H , Hatori A , Shao T , Zhang Y , Yamasaki T , Zhang X , Rong J , Yu Q , Hu K , Fujinaga M , Xie L , Kumata K , Gou Y , Chen J , Gu S , Bao L , Wang L , Collier TL , Vasdev N , Shao Y , Ma JA , Cravatt BF , Fowler C , Josephson L , Zhang MR , Liang SH
Ref : Journal of Medicinal Chemistry , 62 :3336 , 2019
PubMedID: 30829483
Gene_locus related to this paper: human-MGLL

Title : Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors - Poli_2019_J.Enzyme.Inhib.Med.Chem_34_589
Author(s) : Poli G , Lapillo M , Jha V , Mouawad N , Caligiuri I , Macchia M , Minutolo F , Rizzolio F , Tuccinardi T , Granchi C
Ref : J Enzyme Inhib Med Chem , 34 :589 , 2019
PubMedID: 30696302
Gene_locus related to this paper: human-MGLL

Title : Identification of lipases with activity towards monoacylglycerol by criterion of conserved cap architectures - Riegler-Berket_2018_Biochim.Biophys.Acta_1863_679
Author(s) : Riegler-Berket L , Leitmeier A , Aschauer P , Dreveny I , Oberer M
Ref : Biochimica & Biophysica Acta , 1863 :679 , 2018
PubMedID: 29627382
Gene_locus related to this paper: 9bact-TtEst , agrvs-b9jym4 , bac25-mglp , bacsu-cbxnp , human-MGLL , symth-q67mr3 , vibch-VC1974 , yeast-mgll

Title : Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase - Tyukhtenko_2018_Sci.Rep_8_1719
Author(s) : Tyukhtenko S , Rajarshi G , Karageorgos I , Zvonok N , Gallagher ES , Huang H , Vemuri K , Hudgens JW , Ma X , Nasr ML , Pavlopoulos S , Makriyannis A
Ref : Sci Rep , 8 :1719 , 2018
PubMedID: 29379013
Gene_locus related to this paper: human-MGLL

Title : Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation - McAllister_2018_J.Med.Chem_61_3008
Author(s) : McAllister LA , Butler CR , Mente S , O'Neil SV , Fonseca KR , Piro JR , Cianfrogna JA , Foley TL , Gilbert AM , Harris AR , Helal CJ , Johnson DS , Montgomery JI , Nason DM , Noell S , Pandit J , Rogers BN , Samad TA , Shaffer CL , da Silva RG , Uccello DP , Webb D , Brodney MA
Ref : Journal of Medicinal Chemistry , 61 :3008 , 2018
PubMedID: 29498843
Gene_locus related to this paper: human-MGLL

Title : Monoacylglycerol lipase (MAGL) as a promising therapeutic target - Gil-Ordonez_2018_Biochem.Pharmacol_157_18
Author(s) : Gil-Ordonez A , Martin-Fontecha M , Ortega-Gutierrez S , Lopez-Rodriguez ML
Ref : Biochemical Pharmacology , 157 :18 , 2018
PubMedID: 30059673
Gene_locus related to this paper: human-MGLL

Title : Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors - Aida_2018_J.Med.Chem_61_9205
Author(s) : Aida J , Fushimi M , Kusumoto T , Sugiyama H , Arimura N , Ikeda S , Sasaki M , Sogabe S , Aoyama K , Koike T
Ref : Journal of Medicinal Chemistry , 61 :9205 , 2018
PubMedID: 30251836
Gene_locus related to this paper: human-MGLL

Title : Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases - Baggelaar_2017_ACS.Chem.Biol_12_852
Author(s) : Baggelaar MP , van Esbroeck AC , van Rooden EJ , Florea BI , Overkleeft HS , Marsicano G , Chaouloff F , van der Stelt M
Ref : ACS Chemical Biology , 12 :852 , 2017
PubMedID: 28106377
Gene_locus related to this paper: human-ABHD4 , human-ABHD6 , human-ABHD12 , human-DAGLA , human-MGLL

Title : The role of human monoacylglycerol lipase (hMAGL) binding pocket in breakup of unsaturated phospholipid membranes - Karageorgos_2017_Anal.Biochem_536_90
Author(s) : Karageorgos I , Silin VI , Zvonok N , Marino J , Janero DR , Makriyannis A
Ref : Analytical Biochemistry , 536 :90 , 2017
PubMedID: 28822686
Gene_locus related to this paper: human-MGLL

Title : Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase - Butler_2017_J.Med.Chem_60_9860
Author(s) : Butler CR , Beck EM , Harris A , Huang Z , McAllister LA , Am Ende CW , Fennell K , Foley TL , Fonseca K , Hawrylik SJ , Johnson DS , Knafels JD , Mente S , Noell GS , Pandit J , Phillips TB , Piro JR , Rogers BN , Samad TA , Wang J , Wan S , Brodney MA
Ref : Journal of Medicinal Chemistry , 60 :9860 , 2017
PubMedID: 29148769
Gene_locus related to this paper: human-MGLL

Title : Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity - Zhang_2015_Hippocampus_25_16
Author(s) : Zhang Z , Wang W , Zhong P , Liu SJ , Long JZ , Zhao L , Gao HQ , Cravatt BF , Liu QS
Ref : Hippocampus , 25 :16 , 2015
PubMedID: 25131612
Gene_locus related to this paper: human-MGLL

Title : Inhibition of monoacylglycerol lipase reduces nicotine withdrawal - Muldoon_2015_Br.J.Pharmacol_172_869
Author(s) : Muldoon PP , Chen J , Harenza JL , Abdullah RA , Sim-Selley LJ , Cravatt BF , Miles MF , Chen X , Lichtman AH , Damaj MI
Ref : British Journal of Pharmacology , 172 :869 , 2015
PubMedID: 25258021
Gene_locus related to this paper: human-MGLL

Title : Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus - Parker_2015_Psychopharmacology.(Berl)_232_583
Author(s) : Parker LA , Niphakis MJ , Downey R , Limebeer CL , Rock EM , Sticht MA , Morris H , Abdullah RA , Lichtman AH , Cravatt BF
Ref : Psychopharmacology (Berl) , 232 :583 , 2015
PubMedID: 25085768
Gene_locus related to this paper: human-MGLL

Title : In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects - Ignatowska-Jankowska_2014_Br.J.Pharmacol_171_1392
Author(s) : Ignatowska-Jankowska BM , Ghosh S , Crowe MS , Kinsey SG , Niphakis MJ , Abdullah RA , Tao Q , ST ON , Walentiny DM , Wiley JL , Cravatt BF , Lichtman AH
Ref : British Journal of Pharmacology , 171 :1392 , 2014
PubMedID: 23848221
Gene_locus related to this paper: human-MGLL

Title : Mutation of cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency - Laitinen_2014_Mol.Pharmacol_85_510
Author(s) : Laitinen T , Navia-Paldanius D , Rytilahti R , Marjamaa JJ , Karizkova J , Parkkari T , Pantsar T , Poso A , Laitinen JT , Savinainen JR
Ref : Molecular Pharmacology , 85 :510 , 2014
PubMedID: 24368842
Gene_locus related to this paper: human-MGLL

Title : Robust Hydrolysis of Prostaglandin Glycerol Esters by Human Monoacylglycerol Lipase (MAGL) - Savinainen_2014_Mol.Pharmacol_86_522
Author(s) : Savinainen JR , Kansanen E , Pantsar T , Navia-Paldanius D , Parkkari T , Lehtonen M , Laitinen T , Nevalainen T , Poso A , Levonen AL , Laitinen JT
Ref : Molecular Pharmacology , 86 :522 , 2014
PubMedID: 25140003
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL

Title : Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice - Schlosburg_2014_J.Pharmacol.Exp.Ther_350_196
Author(s) : Schlosburg JE , Kinsey SG , Ignatowska-Jankowska B , Ramesh D , Abdullah RA , Tao Q , Booker L , Long JZ , Selley DE , Cravatt BF , Lichtman AH
Ref : Journal of Pharmacology & Experimental Therapeutics , 350 :196 , 2014
PubMedID: 24849924
Gene_locus related to this paper: human-MGLL

Title : Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects - Kinsey_2013_J.Pharmacol.Exp.Ther_345_492
Author(s) : Kinsey SG , Wise LE , Ramesh D , Abdullah R , Selley DE , Cravatt BF , Lichtman AH
Ref : Journal of Pharmacology & Experimental Therapeutics , 345 :492 , 2013
PubMedID: 23412396
Gene_locus related to this paper: human-MGLL

Title : Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase - Aaltonen_2013_Chem.Biol_20_379
Author(s) : Aaltonen N , Savinainen JR , Ribas CR , Ronkko J , Kuusisto A , Korhonen J , Navia-Paldanius D , Hayrinen J , Takabe P , Kasnanen H , Pantsar T , Laitinen T , Lehtonen M , Pasonen-Seppanen S , Poso A , Nevalainen T , Laitinen JT
Ref : Chemical Biology , 20 :379 , 2013
PubMedID: 23521796
Gene_locus related to this paper: human-MGLL

Title : 1,3,4-Oxadiazol-2-ones as fatty-acid amide hydrolase and monoacylglycerol lipase inhibitors: Synthesis, in vitro evaluation and insight into potency and selectivity determinants by molecular modelling - Kasnanen_2013_Eur.J.Pharm.Sci_49_423
Author(s) : Kasnanen H , Minkkila A , Taupila S , Patel JZ , Parkkari T , Lahtela-Kakkonen M , Saario SM , Nevalainen T , Poso A
Ref : Eur J Pharm Sci , 49 :423 , 2013
PubMedID: 23557840
Gene_locus related to this paper: human-MGLL

Title : Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors - Niphakis_2013_ACS.Chem.Neurosci_4_1322
Author(s) : Niphakis MJ , Cognetta AB, 3rd , Chang JW , Buczynski MW , Parsons LH , Byrne F , Burston JJ , Chapman V , Cravatt BF
Ref : ACS Chem Neurosci , 4 :1322 , 2013
PubMedID: 23731016
Gene_locus related to this paper: human-MGLL

Title : Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice - Ramesh_2013_Neuropsychopharmacology_38_1039
Author(s) : Ramesh D , Gamage TF , Vanuytsel T , Owens RA , Abdullah RA , Niphakis MJ , Shea-Donohue T , Cravatt BF , Lichtman AH
Ref : Neuropsychopharmacology , 38 :1039 , 2013
PubMedID: 23303065
Gene_locus related to this paper: human-MGLL

Title : Monoacylglycerol lipase controls endocannabinoid and eicosanoid signaling and hepatic injury in mice - Cao_2013_Gastroenterology_144_808
Author(s) : Cao Z , Mulvihill MM , Mukhopadhyay P , Xu H , Erdelyi K , Hao E , Holovac E , Hasko G , Cravatt BF , Nomura DK , Pacher P
Ref : Gastroenterology , 144 :808 , 2013
PubMedID: 23295443
Gene_locus related to this paper: human-MGLL

Title : Chemical probes of endocannabinoid metabolism - Blankman_2013_Pharmacol.Rev_65_849
Author(s) : Blankman JL , Cravatt BF
Ref : Pharmacol Rev , 65 :849 , 2013
PubMedID: 23512546
Gene_locus related to this paper: human-MGLL

Title : The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model - Ghosh_2013_Life.Sci_92_498
Author(s) : Ghosh S , Wise LE , Chen Y , Gujjar R , Mahadevan A , Cravatt BF , Lichtman AH
Ref : Life Sciences , 92 :498 , 2013
PubMedID: 22749865
Gene_locus related to this paper: human-MGLL

Title : Endocannabinoid enzyme engineering: soluble human thio-monoacylglycerol lipase (sol-S-hMGL) - Karageorgos_2012_ACS.Chem.Neurosci_3_393
Author(s) : Karageorgos I , Zvonok N , Janero DR , Vemuri VK , Shukla V , Wales TE , Engen JR , Makriyannis A
Ref : ACS Chem Neurosci , 3 :393 , 2012
PubMedID: 22860208
Gene_locus related to this paper: human-MGLL

Title : The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors - Savinainen_2012_Acta.Physiol.(Oxf)_204_267
Author(s) : Savinainen JR , Saario SM , Laitinen JT
Ref : Acta Physiol (Oxf) , 204 :267 , 2012
PubMedID: 21418147
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL

Title : Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice - Wise_2012_ACS.Chem.Neurosci_3_369
Author(s) : Wise LE , Long KA , Abdullah RA , Long JZ , Cravatt BF , Lichtman AH
Ref : ACS Chem Neurosci , 3 :369 , 2012
PubMedID: 22860205
Gene_locus related to this paper: human-MGLL

Title : O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors - Niphakis_2012_ACS.Chem.Neurosci_3_418
Author(s) : Niphakis MJ , Johnson DS , Ballard TE , Stiff C , Cravatt BF
Ref : ACS Chem Neurosci , 3 :418 , 2012
PubMedID: 22860211
Gene_locus related to this paper: human-MGLL

Title : Monoacylglycerol lipase - a target for drug development? - Fowler_2012_Br.J.Pharmacol_166_1568
Author(s) : Fowler CJ
Ref : British Journal of Pharmacology , 166 :1568 , 2012
PubMedID: 22428756
Gene_locus related to this paper: human-MGLL

Title : Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates - Chang_2012_Chem.Biol_19_579
Author(s) : Chang JW , Niphakis MJ , Lum KM , Cognetta AB, 3rd , Wang C , Matthews ML , Niessen S , Buczynski MW , Parsons LH , Cravatt BF
Ref : Chemical Biology , 19 :579 , 2012
PubMedID: 22542104
Gene_locus related to this paper: human-MGLL

Title : Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 A resolution - Schalk-Hihi_2011_Protein.Sci_20_670
Author(s) : Schalk-Hihi C , Schubert C , Alexander R , Bayoumy S , Clemente JC , Deckman I , Desjarlais RL , Dzordzorme KC , Flores CM , Grasberger B , Kranz JK , Lewandowski F , Liu L , Ma H , Maguire D , Macielag MJ , McDonnell ME , Mezzasalma Haarlander T , Miller R , Milligan C , Reynolds C , Kuo LC
Ref : Protein Science , 20 :670 , 2011
PubMedID: 21308848
Gene_locus related to this paper: human-MGLL

Title : Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice - Pan_2011_J.Neurosci_31_13420
Author(s) : Pan B , Wang W , Zhong P , Blankman JL , Cravatt BF , Liu QS
Ref : Journal of Neuroscience , 31 :13420 , 2011
PubMedID: 21940435
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum - Zhong_2011_J.Physiol_589_4847
Author(s) : Zhong P , Pan B , Gao XP , Blankman JL , Cravatt BF , Liu QS
Ref : Journal de Physiologie , 589 :4847 , 2011
PubMedID: 21911610
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling - Labar_2010_Chembiochem_11_218
Author(s) : Labar G , Bauvois C , Borel F , Ferrer JL , Wouters J , Lambert DM
Ref : Chembiochem , 11 :218 , 2010
PubMedID: 19957260
Gene_locus related to this paper: human-MGLL

Title : Structural basis for human monoglyceride lipase inhibition - Bertrand_2010_J.Mol.Biol_396_663
Author(s) : Bertrand T , Auge F , Houtmann J , Rak A , Vallee F , Mikol V , Berne PF , Michot N , Cheuret D , Hoornaert C , Mathieu M
Ref : Journal of Molecular Biology , 396 :663 , 2010
PubMedID: 19962385
Gene_locus related to this paper: human-MGLL

Title : Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae - Heier_2010_Biochim.Biophys.Acta_1801_1063
Author(s) : Heier C , Taschler U , Rengachari S , Oberer M , Wolinski H , Natter K , Kohlwein SD , Leber R , Zimmermann R
Ref : Biochimica & Biophysica Acta , 1801 :1063 , 2010
PubMedID: 20554061
Gene_locus related to this paper: human-MGLL , mouse-MGLL , yeast-mgll

Title : Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis - Nomura_2010_Cell_140_49
Author(s) : Nomura DK , Long JZ , Niessen S , Hoover HS , Ng SW , Cravatt BF
Ref : Cell , 140 :49 , 2010
PubMedID: 20079333
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level - Harismendy_2010_Genome.Biol_11_R118
Author(s) : Harismendy O , Bansal V , Bhatia G , Nakano M , Scott M , Wang X , Dib C , Turlotte E , Sipe JC , Murray SS , Deleuze JF , Bafna V , Topol EJ , Frazer KA
Ref : Genome Biol , 11 :R118 , 2010
PubMedID: 21118518
Gene_locus related to this paper: human-MGLL

Title : Characterization of binding properties of monoglyceride lipase inhibitors by a versatile fluorescence-based technique - Savinainen_2010_Anal.Biochem_399_132
Author(s) : Savinainen JR , Yoshino M , Minkkila A , Nevalainen T , Laitinen JT
Ref : Analytical Biochemistry , 399 :132 , 2010
PubMedID: 20005861
Gene_locus related to this paper: human-MGLL

Title : Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons - Straiker_2009_Mol.Pharmacol_76_1220
Author(s) : Straiker A , Hu SS , Long JZ , Arnold A , Wager-Miller J , Cravatt BF , Mackie K
Ref : Molecular Pharmacology , 76 :1220 , 2009
PubMedID: 19767452
Gene_locus related to this paper: human-MGLL

Title : CAY10499, a novel monoglyceride lipase inhibitor evidenced by an expeditious MGL assay - Muccioli_2008_Chembiochem_9_2704
Author(s) : Muccioli GG , Labar G , Lambert DM
Ref : Chembiochem , 9 :2704 , 2008
PubMedID: 18855964
Gene_locus related to this paper: human-MGLL

Title : Disulfiram is an inhibitor of human purified monoacylglycerol lipase, the enzyme regulating 2-arachidonoylglycerol signaling - Labar_2007_Chembiochem_8_1293
Author(s) : Labar G , Bauvois C , Muccioli GG , Wouters J , Lambert DM
Ref : Chembiochem , 8 :1293 , 2007
PubMedID: 17579916
Gene_locus related to this paper: human-MGLL

Title : Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase - Vila_2007_Biochemistry_46_9578
Author(s) : Vila A , Rosengarth A , Piomelli D , Cravatt B , Marnett LJ
Ref : Biochemistry , 46 :9578 , 2007
PubMedID: 17649977
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol - Blankman_2007_Chem.Biol_14_1347
Author(s) : Blankman JL , Simon GM , Cravatt BF
Ref : Chemical Biology , 14 :1347 , 2007
PubMedID: 18096503
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL

Title : The DNA sequence, annotation and analysis of human chromosome 3 - Muzny_2006_Nature_440_1194
Author(s) : Muzny DM , Scherer SE , Kaul R , Wang J , Yu J , Sudbrak R , Buhay CJ , Chen R , Cree A , Ding Y , Dugan-Rocha S , Gill R , Gunaratne P , Harris RA , Hawes AC , Hernandez J , Hodgson AV , Hume J , Jackson A , Khan ZM , Kovar-Smith C , Lewis LR , Lozado RJ , Metzker ML , Milosavljevic A , Miner GR , Morgan MB , Nazareth LV , Scott G , Sodergren E , Song XZ , Steffen D , Wei S , Wheeler DA , Wright MW , Worley KC , Yuan Y , Zhang Z , Adams CQ , Ansari-Lari MA , Ayele M , Brown MJ , Chen G , Chen Z , Clendenning J , Clerc-Blankenburg KP , Davis C , Delgado O , Dinh HH , Dong W , Draper H , Ernst S , Fu G , Gonzalez-Garay ML , Garcia DK , Gillett W , Gu J , Hao B , Haugen E , Havlak P , He X , Hennig S , Hu S , Huang W , Jackson LR , Jacob LS , Kelly SH , Kube M , Levy R , Li Z , Liu B , Liu J , Liu W , Lu J , Maheshwari M , Nguyen BV , Okwuonu GO , Palmeiri A , Pasternak S , Perez LM , Phelps KA , Plopper FJ , Qiang B , Raymond C , Rodriguez R , Saenphimmachak C , Santibanez J , Shen H , Shen Y , Subramanian S , Tabor PE , Verduzco D , Waldron L , Wang Q , Williams GA , Wong GK , Yao Z , Zhang J , Zhang X , Zhao G , Zhou J , Zhou Y , Nelson D , Lehrach H , Reinhardt R , Naylor SL , Yang H , Olson M , Weinstock G , Gibbs RA
Ref : Nature , 440 :1194 , 2006
PubMedID: 16641997
Gene_locus related to this paper: human-AADAC , human-AADACL2 , human-ABHD5 , human-ABHD6 , human-ABHD10 , human-ABHD14A , human-APEH , human-BCHE , human-CIB , human-LIPH , human-MGLL , human-NLGN1 , human-PLA1A

Title : Exon-intron organization and chromosomal localization of the mouse monoglyceride lipase gene - Karlsson_2001_Gene_272_11
Author(s) : Karlsson M , Reue K , Xia YR , Lusis AJ , Langin D , Tornqvist H , Holm C
Ref : Gene , 272 :11 , 2001
PubMedID: 11470505
Gene_locus related to this paper: human-MGLL , mouse-MGLL

Title : A novel poxvirus gene and its human homolog are similar to an E. coli lysophospholipase - Wall_1997_Virus.Res_52_157
Author(s) : Wall EM , Cao J , Chen N , Buller RM , Upton C
Ref : Virus Res , 52 :157 , 1997
PubMedID: 9495531
Gene_locus related to this paper: cowvi-M5L , human-MGLL