2-Heptylquinolin-4(1H)-one

General

Type : Quinoline || Natural

Chemical_Nomenclature : 2-heptyl-1H-quinolin-4-one

Canonical SMILES : CCCCCCCC1=CC(=O)C2=CC=CC=C2N1

InChI : InChI=1S\/C16H21NO\/c1-2-3-4-5-6-9-13-12-16(18)14-10-7-8-11-15(14)17-13\/h7-8,10-12H,2-6,9H2,1H3,(H,17,18)

InChIKey : UYRHHBXYXSYGHA-UHFFFAOYSA-N

Other name(s) : 2-heptyl-4-quinolone,     2-heptyl-4(1H)-quinolone,     TCMDC-132026,     2-Heptyl-4-hydroxyquinoline,     HHQ


MW : 243.35

Formula : C16H21NO

CAS_number : 40522-46-1

PubChem :

UniChem :

Iuphar :

Target

References (5)

Title : Synthesis and biological activity of methylated derivatives of the Pseudomonas metabolites HHQ, HQNO and PQS - Thierbach_2019_Beilstein.J.Org.Chem_15_187
Author(s) : Thierbach S , Wienhold M , Fetzner S , Hennecke U
Ref : Beilstein J Org Chem , 15 :187 , 2019
Abstract : Thierbach_2019_Beilstein.J.Org.Chem_15_187
ESTHER : Thierbach_2019_Beilstein.J.Org.Chem_15_187
PubMedSearch : Thierbach_2019_Beilstein.J.Org.Chem_15_187
PubMedID: 30745993

Title : Rhodococcus erythropolis BG43 Genes Mediating Pseudomonas aeruginosa Quinolone Signal Degradation and Virulence Factor Attenuation - Muller_2015_Appl.Environ.Microbiol_81_7720
Author(s) : Muller C , Birmes FS , Ruckert C , Kalinowski J , Fetzner S
Ref : Applied Environmental Microbiology , 81 :7720 , 2015
Abstract : Muller_2015_Appl.Environ.Microbiol_81_7720
ESTHER : Muller_2015_Appl.Environ.Microbiol_81_7720
PubMedSearch : Muller_2015_Appl.Environ.Microbiol_81_7720
PubMedID: 26319870
Gene_locus related to this paper: rhoer-aqdC1 , rhoer-aqdC2 , rhoer-aqda1

Title : Conversion of the Pseudomonas aeruginosa Quinolone Signal and Related Alkylhydroxyquinolines by Rhodococcus sp. Strain BG43 - Muller_2014_Appl.Environ.Microbiol_80_7266
Author(s) : Muller C , Birmes FS , Niewerth H , Fetzner S
Ref : Applied Environmental Microbiology , 80 :7266 , 2014
Abstract : Muller_2014_Appl.Environ.Microbiol_80_7266
ESTHER : Muller_2014_Appl.Environ.Microbiol_80_7266
PubMedSearch : Muller_2014_Appl.Environ.Microbiol_80_7266
PubMedID: 25239889
Gene_locus related to this paper: rhoer-aqdC1 , rhoer-aqdC2

Title : Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitors - Storz_2012_J.Am.Chem.Soc_134_16143
Author(s) : Storz MP , Maurer CK , Zimmer C , Wagner N , Brengel C , de Jong JC , Lucas S , Musken M , Haussler S , Steinbach A , Hartmann RW
Ref : Journal of the American Chemical Society , 134 :16143 , 2012
Abstract : Storz_2012_J.Am.Chem.Soc_134_16143
ESTHER : Storz_2012_J.Am.Chem.Soc_134_16143
PubMedSearch : Storz_2012_J.Am.Chem.Soc_134_16143
PubMedID: 22992202

Title : Quorum sensing by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species - Dubern_2008_Mol.Biosyst_4_882
Author(s) : Dubern JF , Diggle SP
Ref : Mol Biosyst , 4 :882 , 2008
Abstract : Dubern_2008_Mol.Biosyst_4_882
ESTHER : Dubern_2008_Mol.Biosyst_4_882
PubMedSearch : Dubern_2008_Mol.Biosyst_4_882
PubMedID: 18704225