| Title : Design, synthesis, and pharmacological evaluation of indole-piperidine amides as Blood-brain barrier permeable dual cholinesterase and beta-secretase inhibitors - Banoo_2024_Eur.J.Med.Chem_266_116131 |
| Author(s) : Banoo R , Nuthakki VK , Wadje BN , Sharma A , Bharate SB |
| Ref : Eur Journal of Medicinal Chemistry , 266 :116131 , 2024 |
| Abstract : |
| PubMedSearch : Banoo_2024_Eur.J.Med.Chem_266_116131 |
| PubMedID: 38215587 |
| Title : Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl\/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448 - Nuthakki_2023_ACS.Chem.Neurosci_14_1193 |
| Author(s) : Nuthakki VK , Choudhary S , Reddy CN , Bhatt S , Jamwal A , Jotshi A , Raghuvanshi R , Sharma A , Thakur S , Jadhav HR , Bharate SS , Nandi U , Kumar A , Bharate SB |
| Ref : ACS Chem Neurosci , 14 :1193 , 2023 |
| Abstract : |
| PubMedSearch : Nuthakki_2023_ACS.Chem.Neurosci_14_1193 |
| PubMedID: 36812360 |
| Title : Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and beta-Secretase - Sharma_2023_ACS.Omega_8_11161 |
| Author(s) : Sharma A , Bharate SB |
| Ref : ACS Omega , 8 :11161 , 2023 |
| Abstract : |
| PubMedSearch : Sharma_2023_ACS.Omega_8_11161 |
| PubMedID: 37008108 |
| Title : Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors - Sharma_2023_Bioorg.Chem_139_106719 |
| Author(s) : Sharma M , Sharma A , Thakur S , Nuthakki VK , Jamwal A , Nandi U , Jadhav HR , Bharate SB |
| Ref : Bioorg Chem , 139 :106719 , 2023 |
| Abstract : |
| PubMedSearch : Sharma_2023_Bioorg.Chem_139_106719 |
| PubMedID: 37473478 |
| Title : Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship - Abdullaha_2023_ACS.Omega_8_17591 |
| Author(s) : Abdullaha M , Banoo R , Nuthakki VK , Sharma M , Kaur S , Thakur S , Kumar A , Jadhav HR , Bharate SB |
| Ref : ACS Omega , 8 :17591 , 2023 |
| Abstract : |
| PubMedSearch : Abdullaha_2023_ACS.Omega_8_17591 |
| PubMedID: 37251153 |
| Title : A Coumarin-donepezil Hybrid as a Blood-brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications and Biological Evaluation of Natural Coumarins - Sharma_2022_ChemMedChem__ |
| Author(s) : Sharma A , Nuthakki VK , Gairola S , Singh B , Bharate SB |
| Ref : ChemMedChem , : , 2022 |
| Abstract : |
| PubMedSearch : Sharma_2022_ChemMedChem__ |
| PubMedID: 35892288 |
| Title : Multitargeted C9-substituted ester and ether derivatives of berberrubine for Alzheimer's disease: Design, synthesis, biological evaluation, metabolic stability, and pharmacokinetics - Raghuvanshi_2022_Drug.Dev.Res__ |
| Author(s) : Raghuvanshi R , Jamwal A , Nandi U , Bharate SB |
| Ref : Drug Dev Res , : , 2022 |
| Abstract : |
| PubMedSearch : Raghuvanshi_2022_Drug.Dev.Res__ |
| PubMedID: 36461610 |
| Title : Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors - Sharma_2022_Drug.Dev.Res__ |
| Author(s) : Sharma M , Sharma A , Nuthakki VK , Bhatt S , Nandi U , Bharate SB |
| Ref : Drug Dev Res , : , 2022 |
| Abstract : |
| PubMedSearch : Sharma_2022_Drug.Dev.Res__ |
| PubMedID: 36161804 |
| Title : Blood-brain barrier permeable benzylpiperidin-4-yl-linked benzylamino benzamides as dual cholinesterase inhibitors - Banoo_2022_Drug.Dev.Res__ |
| Author(s) : Banoo R , Nuthakki VK , Abdullaha M , Sharma M , Bharate SB |
| Ref : Drug Dev Res , : , 2022 |
| Abstract : |
| PubMedSearch : Banoo_2022_Drug.Dev.Res__ |
| PubMedID: 36112736 |
| Title : Identification of plant-based multitargeted leads for Alzheimer's disease: In-vitro and in-vivo validation of Woodfordia fruticosa (L.) Kurz - Raghuvanshi_2021_Phytomedicine_91_153659 |
| Author(s) : Raghuvanshi R , Nuthakki VK , Singh L , Singh B , Bharate SS , Bhatti R , Bharate SB |
| Ref : Phytomedicine , 91 :153659 , 2021 |
| Abstract : |
| PubMedSearch : Raghuvanshi_2021_Phytomedicine_91_153659 |
| PubMedID: 34332286 |
| Title : Identification of aplysinopsin as a blood-brain barrier permeable scaffold for anti-cholinesterase and anti-BACE-1 activity - Nuthakki_2020_Bioorg.Chem_107_104568 |
| Author(s) : Nuthakki VK , Yadav Bheemanaboina RR , Bharate SB |
| Ref : Bioorg Chem , 107 :104568 , 2020 |
| Abstract : |
| PubMedSearch : Nuthakki_2020_Bioorg.Chem_107_104568 |
| PubMedID: 33418314 |
| Title : Discovery of Helminthosporin, an Anthraquinone Isolated from Rumex abyssinicus Jacq as a Dual Cholinesterase Inhibitor - Augustin_2020_ACS.Omega_5_1616 |
| Author(s) : Augustin N , Nuthakki VK , Abdullaha M , Hassan QP , Gandhi SG , Bharate SB |
| Ref : ACS Omega , 5 :1616 , 2020 |
| Abstract : |
| PubMedSearch : Augustin_2020_ACS.Omega_5_1616 |
| PubMedID: 32010836 |
| Title : Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase - Abdullaha_2020_Eur.J.Med.Chem_207_112761 |
| Author(s) : Abdullaha M , Nuthakki VK , Bharate SB |
| Ref : Eur Journal of Medicinal Chemistry , 207 :112761 , 2020 |
| Abstract : |
| PubMedSearch : Abdullaha_2020_Eur.J.Med.Chem_207_112761 |
| PubMedID: 32942070 |
| Title : Comparison of the reactivation rates of acetylcholinesterase modified by structurally different organophosphates using novel pyridinium oximes - Bharate_2019_Environ.Toxicol.Pharmacol_71_103218 |
| Author(s) : Bharate SB , Chao CK , Thompson CM |
| Ref : Environ Toxicol Pharmacol , 71 :103218 , 2019 |
| Abstract : |
| PubMedSearch : Bharate_2019_Environ.Toxicol.Pharmacol_71_103218 |
| PubMedID: 31302432 |
| Title : Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors - Nuthakki_2019_Bioorg.Chem_90_103062 |
| Author(s) : Nuthakki VK , Mudududdla R , Sharma A , Kumar A , Bharate SB |
| Ref : Bioorg Chem , 90 :103062 , 2019 |
| Abstract : |
| PubMedSearch : Nuthakki_2019_Bioorg.Chem_90_103062 |
| PubMedID: 31220673 |
| Title : Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent - Nuthakki_2019_Drug.Dev.Res_80_655 |
| Author(s) : Nuthakki VK , Sharma A , Kumar A , Bharate SB |
| Ref : Drug Dev Res , 80 :655 , 2019 |
| Abstract : |
| PubMedSearch : Nuthakki_2019_Drug.Dev.Res_80_655 |
| PubMedID: 31050027 |
| Title : Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship - Manda_2015_Eur.J.Med.Chem_107_1 |
| Author(s) : Manda S , Sharma S , Wani A , Joshi P , Kumar V , Guru SK , Bharate SS , Bhushan S , Vishwakarma RA , Kumar A , Bharate SB |
| Ref : Eur Journal of Medicinal Chemistry , 107 :1 , 2015 |
| Abstract : |
| PubMedSearch : Manda_2015_Eur.J.Med.Chem_107_1 |
| PubMedID: 26560048 |
| Title : Subacute developmental exposure of zebrafish to the organophosphate pesticide metabolite, chlorpyrifos-oxon, results in defects in Rohon-Beard sensory neuron development - Jacobson_2010_Aquat.Toxicol_100_101 |
| Author(s) : Jacobson SM , Birkholz DA , McNamara ML , Bharate SB , George KM |
| Ref : Aquat Toxicol , 100 :101 , 2010 |
| Abstract : |
| PubMedSearch : Jacobson_2010_Aquat.Toxicol_100_101 |
| PubMedID: 20701988 |
| Title : Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase - Bharate_2010_Bioorg.Med.Chem_18_787 |
| Author(s) : Bharate SB , Guo L , Reeves TE , Cerasoli DM , Thompson CM |
| Ref : Bioorganic & Medicinal Chemistry , 18 :787 , 2010 |
| Abstract : |
| PubMedSearch : Bharate_2010_Bioorg.Med.Chem_18_787 |
| PubMedID: 20005727 |
| Title : New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase - Bharate_2009_Bioorg.Med.Chem.Lett_19_5101 |
| Author(s) : Bharate SB , Guo L , Reeves TE , Cerasoli DM , Thompson CM |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :5101 , 2009 |
| Abstract : |
| PubMedSearch : Bharate_2009_Bioorg.Med.Chem.Lett_19_5101 |
| PubMedID: 19640713 |